Pavel Sumazin

Professor

Positions

Professor: Pediatrics
Baylor College of Medicine
Houston, TX, US

Member: Dan L Duncan Comprehensive Cancer Center
Baylor College of Medicine
Houston, Texas, United States

Member: Quantitative and Computational Biosciences
Baylor College of Medicine
Houston, Texas, United States

Addresses

1102 Bates Street (Office): 1220.09
Houston, TX, 77030
United States
sumazin@bcm.edu

Professional Statement

We infer pathophysiological consequences of genomic variants and aberrant gene expression through analyses of molecular profiles. Towards this goal we combine computational analyses and biochemical experiments, identifying new driver genes and interpreting the functional roles of genomic variants that act in cis and in trans.

Websites

Google scholar profile

Open RNA

Selected Publications

Asynchronous Transitions from Hepatoblastoma to Carcinoma " J Hepatol.. 2025 ;
Pubmed PMID: 39763896.
Coordinated regulation by lncRNAs results in tight lncRNA-target couplings " Cell Genomics. 2025 ;
Pubmed PMID: 40628267.
Differentiation Stage Predicts Radiosensitivity in Mesenchymal-Like Pancreatic Cancer " Int J Radiat Oncol Biol Phys .. 2025 ;
Pubmed PMID: 40180058.
Interleukin-15-armoured GPC3 CAR T cells for patients with solid cancers " Nature. 2025 ;
Pubmed PMID: 39604730.
Characterization of Chemoresistant Cell Populations Improves Risk Stratification and Therapy Prediction in Pediatric AML " bioRxiv. 2025 ;
Pubmed PMID: 41256415.
CRISPR/Cas9 gene therapy increases the risk of tumorigenesis in the mouse model of hereditary tyrosinemia type I " JHEP Rep. 2025 ;
Pubmed PMID: 40212789.