Positions

Associate Professor

Pediatrics
Baylor College of Medicine
Houston, TX US

Member

Dan L Duncan Comprehensive Cancer Center
Baylor College of Medicine
Houston, Texas United States

Member

Quantitative and Computational Biosciences
Baylor College of Medicine
Houston, Texas United States

Addresses

1102 Bates Street (Office)

1220.09
Houston, TX 77030
United States
sumazin@bcm.edu

Professional Statement

We infer pathophysiological consequences of genomic variants and aberrant gene expression through analyses of molecular profiles. Towards this goal we combine computational analyses and biochemical experiments, identifying new driver genes and interpreting the functional roles of genomic variants that act in cis and in trans.

Websites

Selected Publications

• H-S Chiu, D Llobet-Navas, X Yang, W-J Chung, A Ambesi-Impiombato, A Iyer, HR Kim, EG Seviour, Z Luo, V Sehgal, T Moss, Y Lu, P Ram, J Silva, GB Mills, A Califano, P Sumazin "Cupid: simultaneous reconstruction of microRNA-target and ceRNA networks." Genome Res. 2015;25(2):257-67.
• Roy A, Kumar V, Zorman B, Fang E, Haines KM, Doddapaneni H, Hampton OA, White S, Bavle AA, Patel NR, Eldin KW, John Hicks M, Rakheja D, Leavey PJ, Skapek SX, Amatruda JF, Nuchtern JG, Chintagumpala MM, Wheeler DA, Plon SE, Sumazin P, Parsons DW "Recurrent internal tandem duplications of BCOR in clear cell sarcoma of the kidney." Nat Commun. 2015 Nov;6(17):8891. Pubmed PMID: 26573325
• P Sumazin, Y Chen, LR. Treviño, SF Sarabia, OA Hampton, K Patel, T-A Mistretta, B Zorman, P Thompson, A Heczey, S Comerford, DA Wheeler, M Chintagumpala, R Meyers, D Rakheja, MJ Finegold, G Tomlinson, DW Parsons, D López-Terrada "Genomic Analysis of Hepatoblastoma Identifies Distinct Molecular and Prognostic Subgroups." Hepatology. 2016;65(1):104-121. Pubmed PMID: 27775819