Positions

Assistant Professor

Mol. & Human Gen.
Baylor College of Medicine
Houston, TX, US

Education

PhD from University of Science and Technology of China

Hefei, China

Professional Interests

• Bone metabolism
• Inborn Errors of Metabolism

Selected Publications

• Zixue Jin*, Brendan Lee* (*co-corresponding). " Boosting glycolysis to combat fragile bone in type 1 diabetes " Cell Chemical Biology. 2023 Sep ;
  Pubmed PMID: 37738949.
• Zixue Jin, Ming-Ming Jiang, Brendan Lee. " Nitric oxide is required for lung alveolarization revealed by deficiency of argininosuccinate lyase " Human Molecular Genetics. 2023 Sep ;
  Pubmed PMID: 37738569.
• Jordan Kho, Urszula Polak, Ming-Ming Jiang, John D Odom, Jill V Hunter, Saima M Ali, Lindsay C Burrage, Sandesh CS Nagamani, Robia G Pautler, Hannah P Thompson, Akihiko Urayama, Zixue Jin, Brendan Lee. " Argininosuccinate lyase deficiency causes blood-brain barrier disruption via nitric oxide–mediated dysregulation of claudin expression " JCI insight. 2023 Sep ;
  Pubmed PMID: 37490345.
• Jin Z, Kho J, Dawson B, Jiang MM, Chen Y, Ali S, Burrage LC, Grover M, Palmer DJ, Turner DL, Ng P, Nagamani SC, Lee B. " Nitric oxide modulates bone anabolism through regulation of osteoblast glycolysis and differentiation " J Clin Invest. 2021 Mar 1;
  Pubmed PMID: 33373331.
• Jin Z, Burrage LC, Jiang MM, Lee YC, Bertin T, Chen Y, Tran A, Gibbs RA, Jhangiani S, Sutton VR, Rauch F, Lee B, Jain M. " Whole-Exome Sequencing Identifies an Intronic Cryptic Splice Site in SERPINF1 Causing Osteogenesis Imperfecta Type VI. " JBMR Plus. 2018 ;
• Jin Z, Wei W, Yang M, Du Y, Wan Y. " Mitochondrial complex I activity suppresses inflammation and enhances bone resorption by shifting macrophage-osteoclast polarization. " Cell Metab. 2014 ;
• Jin Z, Li X, Wan Y. " Nuclear receptor regulation of osteoclast and bone remodeling. " Mol Endocrinol. 2015 ;
• Jin Z, Du Y, Schwaid AG, Asterholm IW, Scherer PE, Saghatelian A, Wan Y. " Maternal adiponectin controls milk composition to prevent neonatal inflammation. " Endocrinology. 2015 ;
• Jin Z, Wei W, Huynh H, Wan Y. " HDAC9 Inhibits Osteoclastogenesis via Mutual Suppression of PPARγ/RANKL Signaling. " Mol Endocrinol. 2015 May ;
• Jin Z, Wei W, Dechow PC, Wan Y. " HDAC7 inhibits osteoclastogenesis by reversing RANKL-triggered β-catenin switch. " Mol Endocrinol. 2013 Feb ;
• Jin Z, Sun R, Wei H, Gao X, Chen Y, Tian Z. " Accelerated liver fibrosis in hepatitis B virus transgenic mice: involvement of natural killer T cells. " Hepatology. 2011 ;

Memberships

American Society for Bone and Mineral Research