Yaxin Wang, Ph.D.
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Yaxin Wang, Ph.D.
Faculty
Positions
- Faculty
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Division of Cardiothoracic Transplantation and Circulatory Support
Baylor College of Medicine
Education
- BA from Xi’an Jiaotong University
- Xi’an, Shaanxi, China
- Engineering
- BSc from RWTH-Aachen University
- Aachen, Germany
- PhD from University of Cambridge,
- Cambridge, United Kingdom
Professional Interests
- Left ventricular assist devices
- Mechanical circulatory support devices
- Organ preservation systems
Professional Statement
Yaxin Wang Payne, PhD's research interests center on the development of left ventricular assist devices (LVADs), with a particular focus on in vitro hemodynamic evaluation and drive system design for axial-flow blood pumps. Additionally, Wang is engaged in advancing ex vivo organ preservation systems for donor lungs. In collaboration with Drs. O. H. Frazier and Nobuyuki Kurita, Wang has secured over $10 million in government grants to support research into next-generation LVAD designs. Working alongside clinical and research partners Drs. Gabriel Loor and Chris Chan, Wang is developing a novel physiologic ex vivo lung perfusion (EVLP) system aimed at enabling long-term preservation and reconditioning of extended-criteria donor organs.Under Wang’s leadership, the IDEA Lab has expanded its research scope in recent years to include pediatric blood pumps, centrifugal LVADs, Fontan assist devices, and advanced ex vivo organ preservation systems.
Selected Publications
- Tran P, Tedesco V, Kiang S, Karnik S, Nguyen D, Frazier OH, Fraser KH, Wang Y "Personalized Numerical Cardiovascular Model with Weight Growth for Evaluating Pediatric Left Ventricular Assist Devices: Derivation from an Experimental Mock Circulatory Loop." Ann Biomed Eng.; Pubmed PMID: 37777691
- L. Nissim, S. Karnik, P. A. Smith, Y. Wang, O. H. Frazier, K. H. Fraser "Machine learning based on computational fluid dynamics enables geometric design optimisation of the NeoVAD blades." Sci Rep.; Pubmed PMID: 37137928
- C. R. Broda, P. A. Smith, Y. Wang, H. Sriraman, P. S.Owuor, L. C. Sampaio, I. Adachi, D. A. Taylor "Construction and Evaluation of a Bio-Engineered Pump to Enable Subpulmonary Support of the Fontan Circulation: A Proof-of-Concept Study." ASAIO J.; Pubmed PMID: 34860713
- Messarra BT, Wang Y, Smith PA, Peak P, Adams DL, Crane TN "3D-Printed silicone anatomic patient simulator to enhance training on cardiopulmonary bypass." J Extra Corpor Technol.; Pubmed PMID: 37378437
- P. A. Smith, Y. Wang, S. A. Bieritz, L. C. Sampaio, W. E. Cohn, R. W. Metcalfe, O. H. Frazier "Design Method Using Statistical Models for Miniature Left Ventricular Assist Device Hydraulics." Ann Biomed Eng.; Pubmed PMID: 30267173
- P. A. Smith, Y. Wang, R. W. Metcalfe, L. C. Sampaio, D. L. Timms, W. E. Cohn, O. H. Frazier "Preliminary design of the internal geometry in a minimally invasive left ventricular assist device under pulsatile-flow conditions." Int J Artif Organs.; Pubmed PMID: 29546808
- Y. Wang, T. G. Logan, P. A. Smith, P-L. Hsu, W. E. Cohn, L. Xu, R. A. McMahon "Systematic Design of a Magnetically Levitated Brushless DC Motor for a Reversible Rotary Intra-Aortic Blood Pump." Artif Organs.; Pubmed PMID: 28929512
- Y. Wang, P. A. Smith, D. L. Timms, P-L. Hsu, R. A. McMahon "In Vitro Evaluation of the Dual-Diffuser Design for a Reversible Rotary Intra-Aortic Ventricular Assist Device." Artif Organs.; Pubmed PMID: 27357189
- Y. Wang, S. Karnik, P. A. Smith, A. Elgalad, O. H. Frazier, N. Kurita "Numerical and Experimental Approach to Characterize a BLDC Motor with Different Radial-gap to Improve Hemocompatibility Performance." 42nd Annual International Conference of the IEEE Engineering in Medicine & Biology Society.; Pubmed PMID: 33018554
- Y. Wang, P. A. Smith, K. Handy, J. Conger, T. Spangler, F. Lin, C. Chen, G. Costas, A. Elgalad, L. C. Sampaio "In Vivo Hemodynamic Evaluation of an Implantable Left Ventricular Assist Device in a Long-term Anti-coagulation Regimen." 42nd Annual International Conference of the IEEE Engineering in Medicine and Biology Society.; Pubmed PMID: 33018536
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