Yan Shi, M.D.

Assistant Professor of Surgery

Positions

Assistant Professor of Surgery: Division of Pediatric Surgery
Baylor College of Medicine

Addresses

Texas Children’s Hospital (Hospital): 6701 Fannin Street
Houston, TX, 77030
United States

Education

Clinical Fellowship at Zucker School of Medicine at Hofstra: New Hyde Park, New York; Pediatric Surgery

Research Fellowship at Baylor College of Medicine/Texas Children’s Hospital: Houston, Texas

Residency at Baylor College of Medicine: Houston, Texas; General Surgery

MD from University of Arkansas for Medical Sciences: Little Rock, Arkansas

Certifications

General Surgery: American Board of Surgery

Pediatric Surgery: American Board of Surgery

Professional Interests

Pediatric surgery

Professional Statement

Dr. Yan Shi is an assistant professor in the Division of Pediatric Surgery. His clinical interests include pediatric surgical oncology, thoracic wall deformities (Nuss procedure), congenital malformations, pilonidal disease, lung lesions and minimally invasive surgery.

Dr. Shi earned his undergraduate degree in cell biology and molecular genetics from the University of Maryland in College Park. He went on to complete a medical degree from the University of Arkansas for Medical Sciences followed by a residency in general surgery at Baylor College of Medicine. During his residency, he completed a fellowship in pediatric surgical oncology research at Baylor College of Medicine and Texas Children’s Hospital. After his residency training, Dr. Shi completed a fellowship in pediatric surgery at Cohen Children’s Medical Center/Northwell Health in Hyde Park, New York.

Dr. Shi was an assistant professor and attending surgeon at Case Western Reserve University/University Hospitals Rainbow Babies and Children’s Hospital in Cleveland, Ohio, before returning to Baylor College of Medicine and Texas Children’s Hospital in 2021.

An avid researcher, Dr. Shi has written several academic papers on topics relating to pediatric malignant tumors, oncology surgery and treatment of solid pediatric tumors. He has also published several noteworthy studies related to the treatment of malignant tumors in children.

Websites

Texas Children's Hospital

Division of Pediatric Surgery

Selected Publications

Shi Y, Kvasnovsky C, Khan S, Jain S, Sargeant D, Lamoshi A, Prince J, Sathya C. " Impact of the COVID-19 pandemic on trauma activations at a pediatric level 1 trauma center in New York " Pediatr Surg Int. ;
Pubmed PMID: 34264357.
Kvasnovsky CL, Shi Y, Rich BS, Glick RD, Soffer SZ, Lipskar AM, Dolgin S, Bagrodia N, Hong A, Prince JM, James DE, Sathya C. " Limiting hospital resources for acute appendicitis in children: Lessons learned from the U.S. epicenter of the COVID-19 pandemic " J Pediatr Surg. ;
Pubmed PMID: 32620267.
Woodfield SE*, Shi Y*, Patel RH, Chen Z, Shah AP, Whitlock RS, Ibarra AM, Larson SR, Sarabia SF, Badachhape A, Starosolski Z, Ghaghada KB, Sumazin P, Annis DA, López-Terrada D, Vasudevan SA. " MDM4 inhibition: a novel therapeutic strategy to reactivate p53 in hepatoblastoma " Sci Rep. ;
Pubmed PMID: 33536467.
Jin J, Jin J, Woodfield SE, Patel RH, Jin NG, Shi Y, Liu B, Sun W, Chen X, Yu Y, Vasudevan SA. " Targeting LRH‑1 in hepatoblastoma cell lines causes decreased proliferation " Oncol Rep. ;
Pubmed PMID: 30320362.
Woodfield SE, Shi Y, Patel RH, Jin J, Major A, Sarabia SF, Starosolski Z, Zorman B, Gupta SS, Chen Z, Ibarra AM, Bissig KD, Ghaghada KB, Sumazin P, López-Terrada D, Vasudevan SA. " A Novel Cell Line Based Orthotopic Xenograft Mouse Model That Recapitulates Human Hepatoblastoma " Sci Rep. ;
Pubmed PMID: 29259231.
Chen Z, Zhao Y, Yu Y, Pang JC, Woodfield SE, Tao L, Guan S, Zhang H, Bieerkehazhi S, Shi Y, Patel R, Vasudevan SA, Yi JS, Muscal JA, Xu GT, Yang J. " Small molecule inhibitor regorafenib inhibits RET signaling in neuroblastoma cells and effectively suppresses tumor growth in vivo " Oncotarget. ;
Pubmed PMID: 29262623.
Shi Y, Commander SJ, Masand PM, Heczey A, Goss JA, Vasudevan SA. " Vascular invasion is a prognostic indicator in hepatoblastoma " J Pediatr Surg. ;
Pubmed PMID: 28347528.
Shi Y, Rojas Y, Zhang W, Beierle EA, Doski JJ, Goldfarb M, Goldin AB, Gow KW, Langer M, Meyers RL, Nuchtern JG, Vasudevan SA. " Characteristics and outcomes in children with undifferentiated embryonal sarcoma of the liver: A report from the National Cancer Database " Pediatr Blood Cancer. ;
Pubmed PMID: 27781381.
Chen Z, Wang L, Yao D, Yang T, Cao WM, Dou J, Pang JC, Guan S, Zhang H, Yu Y, Zhao Y, Wang Y, Xu X, Shi Y, Patel R, Zhang H, Vasudevan SA, Liu S, Yang J, Nuchtern JG. " Wip1 inhibitor GSK2830371 inhibits neuroblastoma growth by inducing Chk2/p53-mediated apoptosis " Sci Rep. ;
Pubmed PMID: 27991505.
Bissig-Choisat B, Kettlun-Leyton C, Legras XD, Zorman B, Barzi M, Chen LL, Amin MD, Huang YH, Pautler RG, Hampton OA, Prakash MM, Yang D, Borowiak M, Muzny D, Doddapaneni HV, Hu J, Shi Y, Gaber MW, Hicks MJ, Thompson PA, Lu Y, et al. " Novel patient-derived xenograft and cell line models for therapeutic testing of pediatric liver cancer " J Hepatol. ;
Pubmed PMID: 27117591.

Memberships

American Pediatric Surgical Association

American Academy of Pediatrics

American College of Surgeons