Positions

Associate Professor

Otolaryngology-Head & Neck Surgery
Baylor College of Medicine
Houston, Texas United States

Core Faculty

Center for Translational Research on Inflammatory Diseases (CTRID)
Michael E. DeBakey VA Medical Center
Baylor College of Medicine
Houston, Texas United States

Member

Dan L Duncan Comprehensive Cancer Center
Baylor College of Medicine
Houston, Texas United States

Addresses

Jamail Specialty Care Center (Clinic)

1977 Butler Blvd.
Suite E5.200
Houston, TX 77030
United States
Phone: (713) 798-5900

Education

MD-PhD from University of Pittsburgh School of Medicine

05/2008 - Pittsburgh, United States

Residency at Baylor College of Medicine, Department of Otolaryngology Head and Neck Surgery

06/2015 - Houston, Texas United States

Clinical Fellowship at University of Texas MD Anderson Cancer Center, Department of Head and Neck Surgery

06/2016 - Houston, Texas United States

Certifications

Diplomate

American Board of Otolaryngology-Head and Neck Surgery

Professional Interests

• Laryngeal and pharyngeal cancer
• Thyroid cancer
• Salivary gland neoplasm
• Melanoma
• Advanced skin cancer

Professional Statement

Vlad C. Sandulache MD, PhD is a board certified otolaryngologist specializing in Head and Neck Surgical Oncology. Dr. Sandulache earned his MD and PhD from the University of Pittsburgh, and completed his residency in Otolaryngology Head and Neck Surgery at Baylor College of Medicine. Following residency, Dr. Sandulache completed a clinical fellowship in the Department of Head and Neck Surgery at The University of Texas MD Anderson Cancer Center where he received advanced training in minimally invasive surgical techniques for pharyngeal and laryngeal malignancies including transoral robotic surgery (TORS) and transoral laser surgery.
Dr. Sandulache utilizes a multidisciplinary approach to the management of patients with head and neck cancer with active participation in both surgical and non-surgical clinical trials. His primary clinical expertise is in the management of early and advanced stage oropharyngeal and laryngeal cancer, salivary gland neoplasms and poorly differentiated and anaplastic thyroid carcinoma.
Dr. Sandulache maintains an active basic science and clinical research program focused on elucidating the link between cancer metabolism and treatment effectiveness. The goal of this research program is to develop personalized treatment strategies based on tumor genomic information and metabolic response to conventional and targeted treatment strategies. One application of this approach currently underway is development of more effective treatments for poorly differentiated and anaplastic thyroid carcinoma.

Websites

Selected Publications

• Richardson PA, Kansara S, Chen GG, Sabichi A, Sikora AG, Parke RB, Donovan DT, Chiao E, Sandulache VC. "Treatment Patterns in Veterans with Laryngeal and Oropharyngeal Cancer and Impact on Survival.." Laryngoscope Investig Otolaryngol. 2018 Aug 9;4(3) Pubmed PMID: 30186958
• Tam S, Sandulache VC, Metwalli KA, Rock CD, Eraj SA, Sheu T, El-Naggar AK, Fuller CD, Weber RS, Lai SY. "Incompletely treated malignancies of the major salivary gland: Toward evidence-based care.." Head Neck. 2018 Aug;40(8):1630-1638. Pubmed PMID: 29734482
• Yu W, Chen Y, Dubrulle J, Stossi F, Putluri V, Sreekumar A, Putluri N, Baluya D, Lai SY, Sandulache VC. "Cisplatin generates oxidative stress which is accompanied by rapid shifts in central carbon metabolism.." Sci Rep. 2018 Mar 9;8(1):4306. Pubmed PMID: 29523854
• Sandulache VC, Michikawa C, Kataria P, Gleber-Netto FO, Bell D, Trivedi S, Rao X, Wang J, Zhao M, Jasser S, Myers JN, Pickering CR. "High-Risk TP53 Mutations Are Associated with Extranodal Extension in Oral Cavity Squamous Cell Carcinoma.." Clin Cancer Res. 2018 Apr 1;24(7):1727-1733. Pubmed PMID: 29330202

Memberships

American Head and Neck Society

Member (06/2015)

Languages

Romanian