Positions
- Associate Professor
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Medicine-Thrombosis
Baylor College of Medicine
Houston, TX, US
- Research Health Scientist
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Center for Translational Research on Inflammatory Diseases (CTRID)
Michael E. DeBakey VA Medical Center
Baylor College of Medicine
Houston, Texas, United States
- Associate Professor
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Molecular Physiology and Biophysics
Baylor College of Medicine
Houston, Texas, United States
- Associate Professor
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Pediatrics
Baylor College of Medicine
Houston, Texas, United States
- Member
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Dan L Duncan Comprehensive Cancer Center
Baylor College of Medicine
Houston, Texas, United States
Addresses
- Center for Translational Research on Inflammatory Diseases (CTRID) (Lab)
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Michael E. DeBakey VA Medical Center
2002 Holcombe Blvd
Houston, TX, 77030
United States
Phone: (713) 770-1822
vvijayan@bcm.edu
Education
- Postdoctoral Fellowship at Johns Hopkins School of Medicine
- Baltimore, Maryland, United States
- PhD from University of Mumbai (Bombay)
- Mumbai/Bombay, India
- MSc from The Maharaja Sayajirao University of Baroda
- Vadodara (Formely Baroda), India
- BSc from University of Mumbai (Bombay)
- Mumbai/Bombay, India
Professional Interests
- Serine/Threonine phosphatases in platelet and endothelial activation
Professional Statement
Platelet and endothelial cell activation are major contributors to the development of coronary artery disease. Although it is widely recognized that activation of these cell types are contingent upon reversible tyrosine, serine (Ser) and threonine (Thr) phosphorylation-dependent assembly of multiple effector proteins in the pathways of signal transduction, much of our current understanding has emerged from studies on protein kinases. The roles of protein phosphatases as control mechanisms during the activation of platelets and endothelial cells are less clear.
The major objective of Dr. Vijayan’s research program has been to clarify how platelet activation and endothelial exocytosis of prothrombotic proteins are coupled with serine/threonine phosphatase driven signal transduction processes. The long term goal is to identify regulators of phosphatases and/or phosphatase interacting proteins that transport Ser/Thr phosphatases to a particular subcellular location, as potential targets for therapeutic interventions in thrombotic and inflammatory events in cardiovascular disease.
The major objective of Dr. Vijayan’s research program has been to clarify how platelet activation and endothelial exocytosis of prothrombotic proteins are coupled with serine/threonine phosphatase driven signal transduction processes. The long term goal is to identify regulators of phosphatases and/or phosphatase interacting proteins that transport Ser/Thr phosphatases to a particular subcellular location, as potential targets for therapeutic interventions in thrombotic and inflammatory events in cardiovascular disease.
Memberships
- American Heart Association (AHA)
- American Society of Hematology (ASH)
- International Society on Thrombosis and Haemostasis (ISTH)
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