Trung
Middle Name
C.
Nguyen, M.D.
Middle Name
C.
Picture
Positions
- Associate Professor
-
Pediatrics-Critical Care
Baylor College of Medicine
Houston, TX US
Addresses
- Texas Children's Hospital - Legacy Tower (Clinic)
-
6651 Main Street, Mail Stop: E1420
Houston, TX 77030
United States
Phone: (832) 826-6230
Education
- Fellowship at University of Pittsburgh School of Medicine
- Pittsburgh, Pennsylvania United States
- National Research Service Award Fellowship Training (T32) (NICHD T32 HD40686) in Pediatric Neurointensive Care and Resuscitation Research, 2001-2003
- Fellowship at University of Pittsburgh School of Medicine
- Pittsburgh, Pennsylvania United States
- Pediatric Critical Care Medicine Fellowship, 1999-2002
- Residency at New York Hospital - Cornell Medical Center
- New York, New York United States
- Pediatric Chief Residency, 1998-99
- Residency at New York Hospital - Cornell Medical Center
- New York, New York United States
- Pediatric Residency, 1996-98
- Residency at New York Hospital - Cornell Medical Center
- New York, New York United States
- Pediatric Internship, 1995-96
- MD from University of Virginia School of Medicine
- Charlottesville, Virginia United States
- 1995
- BA from Cornell University
- Ithaca, New York United States
- Biology, 1991
Certifications
- Pediatric Critical Care Medicine
- American Board of Pediatrics
- General Pedatrics
- American Board of Pediatrics
Honors & Awards
- Distinguished Alumni Award 2020-2021
- The University of Pittsburgh Department of Critical Care Medicine
- Study Section, Invited Reviewer, March 2020, October 2017
- March 2020, October 2017
- National Heart Lung Blood Institute
- Research Mentorship Award Associate Professor Level
- Department of Pediatrics, Baylor College of Medicine, 2017
- Senior Investigator Abstract Award, 2018
- 9th Congress of the World Federation of Pediatric Intensive and Critical Care Societies, 2018
- #1 Abstract Award at the Michael DeBakey Veterans Affairs Medical Center Research Competition, 2018
- Michael DeBakey Veterans Affairs Medical Center Research Competition, 2018
- Society of Critical Care Medicine Presidential Citation
- 2015, 2016, 2019
- Society of Critical Care Medicine, Hematology Specialty Award
- 2013
- Fullbright and Jaworski L.L.P. Faculty Excellence Award for Teaching and Evaluation
- 2011
- Baylor College of Medicine
- Society of Critical Care Medicine Research Citation,
- 2002, 2004, 2008
- Society of Critical Care Medicine Educational Scholarship Award
- 2003
- Society of Critical Care Medicine Annual Scientific Award
- 2001
- Outstanding Medical Teacher Award
- , Cornell University Medical Class of 1999
- Clinical Excellence Award, 1998
- Cornell Pediatric Housestaff, 1998
- The Robert M. Blizzard Pediatric Scholar Award, 1995
- Department of Pediatrics, University of Virginia
Websites
Professional Development
- The Evolution of TAMOF Research
- Workshop (Presenter, 2020)
- Sponsor: The University of Pittsburgh Department of Critical Care Medicine Grand Round
- Therapeutic Plasma Exchange in Critical Illness
- Conference (Presenter, 2020)
- Sponsor: World Federation of Pediatric Intensive and Critical Care Societies Congress
- Sepsis-Induced Multiple Organ Dysfunction Syndromes
- Conference (Presenter, 2020)
- Sponsor: Pediatric Current Concepts, Society of Critical Care Medicine 49th Annual Congress
- Thrombocytopenia-Associated Multiple Organ Failure
- Conference (Presenter, 2019)
- Sponsor: Pediatric Critical Care Summit of The Americas, 15th Latin American Congress of Pediatric Intensive Care and 26th Pediatric Critical Care Colloquium U.S.A.
- Plasma Therapies and Beyond
- Conference (Presenter, 2015)
- Sponsor: Society of Critical Care 44th Annual Congress
- Pediatric Multiple Organ Dysfunction Syndrome Workshop
- Conference (Presenter, 2015)
- Sponsor: National Institute of Health – Eunice Kennedy Shriver National Institute of Child Health and Human Development
- Sepsis Phenotypes: Targets for Blood Purification
- Conference (Presenter, 2014)
- Sponsor: Acute Dialysis Quality Initiative XIV Consensus Conference
- Red, White and Purple: The Colors of Sepsis-induced Multiple Organ Failure
- Conference (Presenter, 2014)
- Sponsor: Pediatric Grand Round at MD Anderson Cancer Center
Selected Publications
- • Valladolid C, Martinez-Vargas M, Sekhar N, Lam F, Brown C, Palzkill T, Tischer A, Auton M, Vijayan KV, Rumbaut RE, Nguyen TC, Cruz MA "Modulating the Rate of Fibrin Formation and Clot Structure Attenuates Microvascular Thrombosis in Systemic Inflammation." Blood Adv. 2020 April 14; 4 ((7)): 1340-1349. Pubmed PMID: 32259201
- • Weiss SL, Peters MJ, Alhazzani W, … Nguyen TC, et al "Executive summary: surviving sepsis campaign international guidelines for the management of septic shock and sepsis-associated organ dysfunction in children.." Intensive Care Med. 2020 February ; 46 (Suppl 1): 1-9. Pubmed PMID: 32030528
- • Weiss SL, Peters MJ, Alhazzani W, …Nguyen TC, et al "Surviving sepsis campaign international guidelines for the management of septic shock and sepsis-associated organ dysfunction in children.." Intensive Care Med. 2020 February 7; 46 (Suppl 1): 10-67. Pubmed PMID: 32030529
- • Steen EH, Lasa JJ, Nguyen TC, Keswani SG, Checchia PA, Anders MM "Central Venous Catheter-Related Deep Vein Thrombosis in the Pediatric Cardiac Intensive Care Unit." J Surg Res. 2019 September ; 241 : 149-159. Pubmed PMID: 31026798
- • Fortenberry JD, Nguyen T, Grunwell JR, Aneja RK, Wheeler D, Hall M, Fleming G, Tarrago R, Buttram S, Dalton H, et al "Therapeutic Plasma Exchange in Children With Thrombocytopenia-Associated Multiple Organ Failure: The Thrombocytopenia-Associated Multiple Organ Failure Network Prospective Experience." Crit Care Med. 2019 March ; 47 ((3)): e173-e181. Pubmed PMID: 30531184
- • Gorgis NM, Kennedy C, Lam F, Thompson K, Coss-Bu J, Akcan Arikan A, Nguyen T, Hosek K, Miloh T, Karpen SJ et al "Clinical Consequences of Cardiomyopathy in Children With Biliary Atresia Requiring Liver Transplantation." Hepatology. 2019 March ; 69 ((3)): 1206-1218. Pubmed PMID: 30076624
- Goldman J, Desai MS, McClain KL, Tcharmtchi MH, Kennedy CE, Thompson K, Lam F, Bashir DA, Chinn IK, Goldberg BR, Allen CE, Nguyen TC. "Hepatobiliary Dysfunction and Disseminated Intravascular Coagulation Increase Risk of Mortality in Pediatric Hemophagocytic Lymphohistiocytosis." Pediatr Crit Care Med. 2019 October ; 19 ((10)): e522-e530. Pubmed PMID: 30113519
- • Akcan Arikan A, Srivaths P, Himes RW, Tufan Pekkucuksen N, Lam F, Nguyen T, Miloh T, Braun M, Goss J, and Desai MS. "Hybrid Extracorporeal Therapies as a Bridge to Pediatric Liver Transplantation." Pediatr Crit Care Med. 2018 July ; 19 ((7)): e342-e349. Pubmed PMID: 29652753
- • Chinn IK, Eckstein OS, Peckham-Gregory EC, Goldberg BR, Forbes LR, Nicholas SK, Mace EM, Vogel TP, Abhyankar HA, Diaz MI, Heslop HE, Krance RA, Martinez CA, Nguyen TC, Bashir DA, Goldman JR et al. "Genetic and Mechanistic Diversity in Pediatric Hemophagocytic Lymphohistiocytosis." Blood. 2018 July ; 132 ((1)): 89-100. Pubmed PMID: 6034641
- Sims CR, Singh SP, Mu S, Gokden N, Zakaria D, Nguyen TC, Mayeux PR "Rolipram Improves Outcome in a Rat Model of Infant Sepsis-Induced Cardiorenal Syndrome." Front Pharmacol. 2017 May 3; 8 : 237. Pubmed PMID: 28515693
- Davis AL, Carcillo JA, Aneja RK, Deymann AJ, Lin JC, Nguyen TC, Okhuysen-Cawley RS, Relvas MS, Rozenfeld RA, Skippen PW, et al "American College of Critical Care Medicine Clinical Practice Parameters for Hemodynamic Support of Pediatric and Neonatal Septic Shock." Crit Care Med. 2017 June ; 45 (6): 1061-1093. Pubmed PMID: 28509730
- Wong HR, Cvijanovich NZ, Anas N, Allen GL, Thomas NJ, Bigham MT, Weiss SL, Fitzgerald J, Checchia PA, Meyer K, Quasney M, Hall M, Gedeit R, Freishtat RJ, Nowak J, Raj SS, Gertz S, Howard K, Harmon K, Lahni P, Frank E, Hart KW, Nguyen TC, Lindsell CJ "Pediatric Sepsis Biomarker Risk Model-II: Redefining the Pediatric Sepsis Biomarker Risk Model With Septic Shock Phenotype." Crit Care Med. 2016 November ; 44 (11): 2010-2017. Pubmed PMID: 27513537
- • Nguyen TC, Gushiken F, Correa JI, et al. "A recombinant fragment of von Willebrand factor reduces fibrin-rich microthrombi formation in mice with endotoxemia.." Thrombosis Research. 2015 March ; 135 ((5)): 1025-1030. Pubmed PMID: 25769494
- Nguyen TC, Han YY, Kiss JE, Hall MW, Hassett AC, Jaffe R, Orr RA, Janosky J, Carcillo JA "Intensive plasma exchange increases a disintegrin and metalloprotease with thrombospondin motifs-13 activity and reverses organ dysfunction in children with thrombocytopenia-associated multiple organ failure.." Crit. Care Med.. 2008 October ; 36 (10): 2878-87. Pubmed PMID: 18828196
Memberships
- American Academy of Pediatrics
- Society of Critical Care Medicine
- Academia Colombiana De Medicina Critica (ACOMEC)
- Honorary Member, 2014
- Baylor College of Medicine Affiliated Hospital
- Member of Steering Committee
- Society of Critical Medicine and European Society of Intensive Care Medicine
- Invited Committee Member
Funding
- Microvascular Thrombosis in Systemic Inflammation - #2R01GM112806-05A1 (09/05/2013 - 06/30/2023) Grant funding from National Institute of Health NIGMS
- Multi-Principle Investigator RO1 Role: Principle Investigator
- Novel Treatment for DIC - #R41 HL135942 (08/20/2018 - 07/30/2020) Grant funding from National Institute of Health NIGMS
- Small Business Technology Transfer Grant Role: Co-Investigator 8/20/2018-7/31/2019, No Cost Extension 7/30/2020
- Defining Pathologic Immune Dysregulation in COVID19: Opportunities for Risk Stratification and Therapeutic Immune Modulation - #P30 CA125123 (05/01/2020 - 04/30/2021) Grant funding from NCI
- (COVID19 Supplement to Dan L Duncan Comprehensive Cancer Center P30) Role: Co-Investigator (05/01/20-04/30/2021; (Osborne, DLDCCC PI)
- Characterisation of Sepsis-Induced Diaphragm Dysfunction in Critically Ill Children (10/01/2019 - 03/31/2021) Grant funding from Texas Children’s Hospital Pediatric Pilot Research Award
- Role: Mentor for Principle Investigator Awardee Manpreet Virk, MD
- ADAMTS-13 and Inflammation - #K08 GM83212 (05/01/2008 - 05/31/2014) Grant funding from National Institute of Health
- Principal Investigator No Cost Extension 5/31/2014
- The Role of Microvesicles in Sepsis-Induced Disseminated Intravascular Coagulation (07/01/2005 - 06/30/2008) Grant funding from American Heart Association, Beginning Grant-In-Aid
- American Heart Association, Beginning Grant-In-Aid Role: Principal Investigator CLOSED
- Microvesicles and Disseminated Intravascular Coagulation - #K12 HD 41648 (12/01/2004 - 12/31/2006) Gift funding from National Institutes of Health K12 (Child Health Research Center, New Project Development Award
- CLOSED
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