Thomas Eugene Lloyd, M.D., Ph.D.

Chair

Email

u250998@bcm.edu

Positions

Chair: Neurology
Baylor College of Medicine
Houston, Texas, United States

Education

Fellowship at Johns Hopkins Hospital: Baltimore, Md.; Neuromuscular Medicine

Residency at Johns Hopkins Hospital: Baltimore, Md.; Neurology

Internship at Johns Hopkins Hospital: Baltimore, Md.; Internal Medicine

MD from Baylor College of Medicine: Houston, Texas, United States; Graduated with Honors

PhD from Baylor College of Medicine: Houston, Texas, United States; Molecular and Cell Biology

BA from Rice University: Houston, Texas, United States; Chemistry and Biochemistry

Certifications

Neurology: American Board of Psychiatry and Neurology

Websites

Dr. Lloyd's Bibliography

Comprehensive list of publications and presentations

Selected Publications

Lloyd TE, Atkinson R, Wu MN, Zhou Y, Pennetta G, Bellen HJ. " Hrs regulates endosome membrane invagination and tyrosine kinase receptor signaling in Drosophila " Cell. 2002 ; 108 (2) : 261-9.
Pubmed PMID: 11832215.
Lloyd TE, Machamer J, O'Hara K, Kim JH, Collins SE, Wong MY, et al.. " The p150(Glued) CAP-Gly domain regulates initiation of retrograde transport at synaptic termini " Neuron. 2012 ; 74 (2) : 344-60.
Pubmed PMID: 22542187.
Lloyd TE, Mammen AL, Amato AA, Weiss MD, Needham M, Greenberg SA. " Evaluation and construction of diagnostic criteria for inclusion body myositis " Neurology. 2014 ; 83 (5) : 426-33.
Pubmed PMID: 24975859.
Zhang K, Donnelly CJ, Haeusler AR, Grima JC, Machamer JB, Steinwald P, et al.. " The C9ORF72 repeat expansion disrupts nucleocytoplasmic transport " Nature. 2015 ; 525 (7567) : 56-61.
Pubmed PMID: 26308891.
Zhang K, Daigle JG, Cunningham KM, Coyne AN, Ruan K, Grima JC, et al.. " Stress granule assembly disrupts nucleocytoplasmic transport " Cell. 2018 ; 173 (4) : 958-71 e17.
Pubmed PMID: 29628143.
Vogler TO, Wheeler JR, Nguyen ED, Hughes MP, Britson KA, Lester E, et al.. " TDP-43 and RNA form amyloid-like myo-granules in regenerating muscle " Nature. 2018 ; 563 (7732) : 508-13.
Pubmed PMID: 30464263.
Cunningham KM, Maulding K, Ruan K, Senturk M, Grima JC, Sung H, et al.. " TFEB/Mitf links impaired nuclear import to autophagolysosomal dysfunction in C9-ALS " elife. 2020 ; 9
Pubmed PMID: 33300868.
Woolums BM, McCray BA, Sung H, Tabuchi M, Sullivan JM, Ruppell KT, et al.. " TRPV4 disrupts mitochondrial transport and causes axonal degeneration via a CaMKII-dependent elevation of intracellular Ca(2) " Nat Commun. 2020 ; 11 (1) : 2679.
Pubmed PMID: 32471994.
Britson KA, Ling JP, Braunstein KE, Montagne JM, Kastenschmidt JM, Wilson A, et al.. " Loss of TDP-43 function and rimmed vacuoles persist after T cell depletion in a xenograft model of sporadic inclusion body myositis " Sci Transl Med. 2022 ; 14 (628) : eabi9196.
Pubmed PMID: 35044790.
Dubey SK, Maulding K, Sung H, Lloyd TE. " Nucleoporins are degraded via upregulation of ESCRT-III/Vps4 complex in Drosophila models of C9-ALS/FTD " Cell Rep. 2022 ; 40 (12) : 111379.
Pubmed PMID: 36130523.