Steven Wesley Wall, Ph.D.

Postdoctoral Associate

Email

steven.wall@bcm.edu

Positions

Postdoctoral Associate: Breast Center - Echeverria
Baylor College of Medicine

Addresses

One Baylor Plaza (Lab): Echeverria Lab - R531C
Houston, TX, 77030
United States

Education

PhD from Texas A&M University: 12/2022 - College Station, Texas, United States

BS from Texas A&M University: 05/2012 - College Station, Texas, United States

Professional Statement

My focus is on understanding how residual triple negative breast cancer cells after neoadjuvant chemotherapy rewire their metabolism with respect to reduction-oxidation (redox) reaction co-factors NAD, NADP, & FAD. This knowledge will provide a framework in which to design interventions to further exacerbate redox imbalance leading to increased chemotherapy sensitivity.

Websites

NCBI Bibliography

Selected Publications

Wall SW, Sanchez L, Tuttle KS, Pearson SJ, Soma S, Wyatt GL, Carter HN, Jenschke RM, Tan L, Martinez SA, Lorenzi PL, Gohil VM, Rijnkels M, Porter WW. " Noncanonical role of singleminded-2s in mitochondrial respiratory chain formation in breast cancer " Exp Mol Med. 2023 May ;
Pubmed PMID: 37121978.
Berner MJ, Wall SW, Echeverria GV. " Deregulation of mitochondrial gene expression in cancer: mechanisms and therapeutic opportunities " Br J Cancer. 2024 Aug ;
Pubmed PMID: 39143326.
Wall SW, Echeverria GV. " Avoiding Extinction: Cancer-Associated Fibroblasts Help Triple-Negative Breast Cancer Outrun Chemotherapy " Cancer Res. 2023 Nov ;
Pubmed PMID: 37964615.
Sanchez L, Epps J, Wall S, McQueen C, Pearson SJ, Scribner K, Wellberg EA, Giles ED, Rijnkels M, Porter WW. " SIM2s directed Parkin-mediated mitophagy promotes mammary epithelial cell differentiation " Cell Death Differ. 2023 Jun ;
Pubmed PMID: 36966227.
select Pearson SJ, Roy Sarkar T, McQueen CM, Elswood J, Schmitt EE, Wall SW, Scribner KC, Wyatt G, Barhoumi R, Behbod F, Rijnkels M, Porter WW. " ATM-dependent activation of SIM2s regulates homologous recombination and epithelial-mesenchymal transition " Oncogene. 2019 Apr ;
Pubmed PMID: 30531838.
Wyatt GL, Crump LS, Young CM, Wessells VM, McQueen CM, Wall SW, Gustafson TL, Fan YY, Chapkin RS, Porter WW, Lyons TR. " Cross-talk between SIM2s and NFκB regulates cyclooxygenase 2 expression in breast cancer " Breast Cancer Res. 2019 Nov ;
Pubmed PMID: 31783895.

Funding

T32 Translational Breast Cancer Research Training Program #T32CA203690: (02/01/2023); Grant funding from National Institutes of Health, National Cancer Institute