Reina Villareal
Picture
Reina Villareal
Associate Professor
Positions
- Associate Professor
-
Medicine-Endocrinology
Baylor College of Medicine
Houston, TX, US
Addresses
- Michael E. DeBakey VA Medical Center (Hospital)
-
2002 Holcombe
Building 100, Room 240
Houston, TX 77030
United States
(713) 794-7534
Education
- Fellowship at Washington University School of Medicine
- St. Louis, Missouri, United States
- Residency at Texas Tech University
- Amarillo, Texas, United States
- MD from Cebu Institute of Medicine
- Cebu, Philippines
Certifications
- American Board of Internal Medicine
Professional Interests
- CYP450 enzyme genes in gonadal hormone and bone metabolism
- Aromatase inhibitors and weight loss in severely obese men with hypogonadism
Professional Statement
I am an endocrinologist with interest in the interaction between genetics, gonadal hormones and bone.Websites
Selected Publications
- Colleluori G, Aguirre LE, Qualls C, Chen R, Napoli N, Villareal DT, Armamento-Villareal R "Adipocytes ESR1 Expression, Body Fat and Response to Testosterone Therapy in hypogonadal Men Vary According to Estradiol Levels." Nutrients.. 2018 September 4; 10 (9): E1226.. Pubmed PMID: 30181488
- Villareal DT, Aguirre L, Gurney AB, Waters DL, Sinacore DR, Colombo E, Armamento-Villareal R, Qualls C "Aerobic or Resistance Exercise, or Both, in Dieting Obese Older Adults.." N Engl J Med. 2017 May 18; 376 (20): 1943-1955. Pubmed PMID: 28514618
- Armamento-Villareal R, Aguirre L, Napoli N, Shah K, Hilton T, Sinacore DR, Qualls C, Villareal DT "Changes in thigh muscle volume predict bone mineral density response to lifestyle therapy in frail, obese older adults." Osteoporos Int.. 2014 February ; 25 (2): 551-8. Pubmed PMID: 23892583
- . Armamento-Villareal R, Aguirre LE, Qualls C, Villareal DT "Effect of Lifestyle Intervention on the Hormonal Profile of Frail Obese Older Men. J Nutr Health Aging." J Nutr Health Aging. 2016 20 (3): 334-40. Pubmed PMID: 26892583
- "Effect of Weight Loss, Exercise, or Both on Undercarboxylated Osteocalcin and Insulin Secretion in Frail, Obese Older Adults." Oxid Med Cell Longev.. 2017 : Pubmed PMID: 28951766
- Shah K, Armamento-Villareal R, Parimi N, Chode S, Sinacore DR, Hilton TN, Napoli N, Qualls C, Villareal DT "Exercise training in obese older adults prevents increase in bone turnover and attenuates decrease in hip bone mineral density induced by weight loss despite decline in bone-active hormones." J Bone Miner Res. 2011 December ; 26 (12): 2851-9. Pubmed PMID: 21786319
- Georgia Colleluori, Rui Chen, Nicola Napoli, Lina E. Aguirre, Clifford Qualls, Dennis T. Villareal and Reina Armamento-Villareal "Fat Mass Follows a U-Shaped Distribution Based on Estradiol Levels in Postmenopausal Women." Front Endocrinol (Lausanne). 2018 July 2; 9 : 315. Pubmed PMID: 30013511
- Napoli N, Rastelli A, Ma C, Yarramaneni J, Vattikutti S, Moskowitz G, Giri T, Mueller C, Kulkarny V, Qualls C, Ellis M, Armamento-Villareal R "Genetic polymorphism at Val80 (rs700518) of the CYP19A1 gene is associated with aromatase inhibitor associated bone loss in women with ER + breast cancer." Bone. 2013 August ; 55 (2): 309-14. Pubmed PMID: 23643682
- Napoli N, Rastelli A, Ma C, Colleluori G, Vattikuti S, Armamento-Villareal R. "Genetic polymorphism at Val80 (rs700518) of the CYP19A1 gene is associated with body composition changes in women on aromatase inhibitors for ER (+) breast cancer." Pharmacogenet Genomics. 2015 June ; : Pubmed PMID: 26049585
- Lina E. Aguirre, Georgia Colleluori, Kenneth E. Fowler, Irum Zeb Jan, Kenneth Villareal, Clifford Qualls, David Robbins, Dennis T. Villareal, Reina Armamento-Villareal "High Aromatase Activity in Hypogonadal Men is Associated with Higher Spine BMD, Increased Truncal Fat and Reduced Lean Mass, In Press." European Journal of Endocrinology. 2015 :
- Aguirre LE, Colleluori G, Fowler KE, Jan IZ, Villareal K, Qualls C, Robbins D, Villareal DT, Armamento-Villareal R "High aromatase activity in hypogonadal men is associated with higher spine bone mineral density, increased truncal fat and reduced lean mass." Eur J Endocrinol.. 2015 August ; 173 (2): 167-74. Pubmed PMID: 26142101
- Aguirre LE, Colleluori G, Dorin R, Robbins D, Chen R, Jiang B, Qualls C, Villareal DT, Armamento-Villareal R. Hypogonadal Men with Higher Body Mass Index have Higher Bone Density and Better Bone Quality but Reduced Muscle Density "Hypogonadal Men with Higher Body Mass Index have Higher Bone Density and Better Bone Quality but Reduced Muscle Density." Calcif Tissue Int.. 2017 December ; 101 (6): 602-611. Pubmed PMID: 28856390
- Colleluori G, Aguirre L, Dorin R, Robbins D, Blevins D, Barnouin Y, Chen R, Qualls C, Villareal DT, Armamento-Villareal R "Hypogonadal men with type 2 diabetes mellitus have smaller bone size and lower bone turnover." Bone.. 2017 March 16; 99 : 14-19. Pubmed PMID: 28323146
- Napoli N, Vattikuti S, Yarramaneni J, Giri TK, Nekkalapu S, Qualls C, Armamento-Villareal RC "Increased 2-hydroxylation of estrogen is associated with lower body fat and increased lean body mass in postmenopausal women." Maturitas. 2012 May ; 72 (1): 66-71. Pubmed PMID: 22385932
- Aguirre L, Napoli N, Waters D, Qualls C, Villareal DT, Armamento-Villareal R "Increasing adiposity is associated with higher adipokine levels and lower bone mineral density in obese older adults." J Clin Endocrinol Metab. 2014 September ; 99 (9): 3290-7. Pubmed PMID: 24878039
- Armamento-Villareal R, Shah VO, Aguirre LE, Meisner AL, Qualls C, Royce ME "Polymorphisms in CYP19A1 Are Associated with Disease Progression among Patients with Breast Cancer from Different Racial/Ethnic Backgrounds." Front Genet.. 2016 December 2; 7 : 211. Pubmed PMID: 27994616
- Armamento-Villareal R, Wingkun N, Aguirre LE, Kulkarny V, Napoli N, Colleluori G, Qualls C, Villareal DT "The FTO gene is associated with a paradoxically favorable cardiometabolic risk profile in frail, obese older adults." Pharmacogenet Genomics. 2015 December ; : Pubmed PMID: 26709911
- Rastelli AL, Taylor ME, Gao F, Armamento-Villareal R, Jamalabadi-Majidi S, Napoli N, Ellis MJ "Vitamin D and aromatase inhibitor-induced musculoskeletal symptoms (AIMSS): a phase II, double-blind, placebo-controlled, randomized trial." Breast Cancer Res Treat. 2011 August ; 129 (1): 107-16. Pubmed PMID: 21691817
- Armamento-Villareal R, Sadler C, Napoli N, Shah K, Chode S, Sinacore DR, Qualls C, Villareal DT "Weight loss in obese older adults increases serum sclerostin and impairs hip geometry but both are prevented by exercise training." J Bone Miner Res. 2012 May ; 27 (5): 1215-21. Pubmed PMID: 22392834
- Bouchonville M, Armamento-Villareal R, Shah K, Napoli N, Sinacore DR, Qualls C, Villareal DT "Weight loss, exercise or both and cardiometabolic risk factors in obese older adults: results of a randomized controlled trial." Int J Obes (Lond). 2014 March ; 38 (3): 423-31. Pubmed PMID: 23823329
- Villareal DT, Chode S, Parimi N, Sinacore DR, Hilton T, Armamento-Villareal R, Napoli N, Qualls C, Shah K "Weight loss, exercise, or both and physical function in obese older adults." N Engl J Med. 2011 March 31; 364 (13): 1218-29. Pubmed PMID: 21449785
Projects
- Aromatase inhibitors and weight loss in severely obese men with hypogonadism
- (08/2017 - 06/2022)
Memberships
- Endocrine Society
- American Society for Bone and Mineral Research
- American Association of Clinical Endocrinologists
- American College of Physicians
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