Patricia Castro, Ph.D.

Associate Professor

(713) 798-6795

Email

pcastro@bcm.edu

Positions

Associate Professor: Pathology & Immunology
Baylor College of Medicine
Houston, TX, US

Director, Human Tissue Acquisition and Pathology Shared Resource: Advanced Technology Cores
Baylor College of Medicine
Houston, Texas, United States

Addresses

Baylor College of Medicine (Office): One Baylor Plaza
Department of Pathology & Immunology
Houston, TX, 77030
United States
Phone: (713) 798-6795
pcastro@bcm.edu

Education

PhD from University Of Texas Health Science Center: 01/2001 - Houston, Texas, United States; Molecular Genetics, Molecular Biology

BA from University of Pittsburgh: 05/1992 - Pittsburgh, Pennsylvania, United States

Professional Statement

I am the Laboratory Director of the Human Tissue Acquisition and Pathology Core at Baylor College of Medicine. As the Core director, my role is to facilitate the collection, processing and molecular analysis of human tissues and I manage services for histology, immunohistochemistry, and imaging of research tissues from mouse or human origin. My research interests are primarily in the field of cancer biology and my goals are geared toward directly or indirectly impacting the lives and outcomes for cancer patients. This appointment allows me to help facilitate the research of my peers at BCM through tissue distribution and specialized laboratory expertise.

Selected Publications

Castro P, Giri D, Lamb D, Ittmann M. " Cellular senescence in the pathogenesis of benign prostatic hyperplasia. " Prostate. 2003 Apr 1; 55 (1) : 30-8.
Pubmed PMID: 12640658.
Castro PD, Liang JC, Nagarajan L. " Deletions of chromosome 5q13.3 and 17p loci cooperate in myeloid neoplasms. " Blood. 2000 Mar 15; 95 (6) : 2138-43.
Pubmed PMID: 10706886.
Castro P, Creighton CJ, Ozen M, Berel D, Mims MP, Ittmann M. " Genomic profiling of prostate cancers from African American men. " Neoplasia. 2009 Mar ; 11 (3) : 305-12.
Pubmed PMID: 19242612.
Cancer Genome Atlas Research Network.. " Comprehensive molecular characterization of urothelial bladder carcinoma. " Nature. 2014 Mar 20; 507 (7492) : 315-322.
Pubmed PMID: 24476821.
Castro P, Liang H, Liang JC, Nagarajan L.. " A novel, evolutionarily conserved gene family with putative sequence-specific single-stranded DNA-binding activity. " Genomics. 2002 Jul ; 80 (1) : 78-85.
Pubmed PMID: 12079286.
Liang H, Castro PD, Ma J, Nagarajan L. " Finer delineation and transcript map of the 7q31 locus deleted in myeloid neoplasms. " Cancer Genet. Cytogenet.. 2005 Oct 15; 162 (2) : 151-9.
Pubmed PMID: 16213364.
Castro PD, Fairman J, Nagarajan L. " The unexplored 5q13 locus: a role in hematopoietic malignancies. " Leuk. Lymphoma. 1998 Aug ; 30 (41400) : 443-8.
Pubmed PMID: 9711906.
Vital P, Castro P, Ittmann M.. " Oxidative stress promotes benign prostatic hyperplasia. " Prostate. 2015 Sep 29;
Pubmed PMID: 26417670.
Castro P, Corredor G, Koyuncu C, Nordstrom LA, Tiji M, Leavitt T, Lewis JS Jr, Madabhushi A, Frederick MJ, Sandulache VC. " Recurrent Oropharyngeal Squamous Cell Carcinomas Maintain Anti-tumor Immunity and Multinucleation Levels Following Completion of Radiation. " Head Neck Pathol.. 2023 Dec ; 17 (4) : 952-960.
Pubmed PMID: 37995073.
Sayed S, Koka H, Abubakar M, Gardner K, Salgado R, Moloo Z, Caban-Ureña AB, Rosen D, Castro P, Saleh M, Shaikh AJ, Shah J, Figueroa J, Makokha F, Ha HK, Wang Z, Magangane P, Naidoo R, Ngundo V, Yang XR, Govender D. " Tumour Infiltrating Lymphocytes (TILs) and immune composition in breast cancer patients from Kenya: Spatial distributions and associations with risk factors and tumour characteristics. " Breast Cancer Res Treat.. 2023 Jun ; 199 (2) : 401-413.
Pubmed PMID: 37010652.
Villanueva H, Wells GA, Miller MT, Villanueva M, Pathak R, Castro P, Ittmann MM, Sikora AG, Lerner SP. " Characterizing treatment resistance in muscle invasive bladder cancer using the chicken egg chorioallantoic membrane patient-derived xenograft model. " Heliyon.. 2022 Dec ; 8 (12) : e12570.
Pubmed PMID: 36643309.