Email

katsonis@bcm.edu

Positions

Assistant Professor

Molecular & Human Genetics
Baylor College of Medicine
Houston, TX US

Professional Statement

Panos is the developer of the Evolutionary Action method that estimates the functional and clinical impact of genetic variants. His research focuses on using Evolutionary Action to interpret any protein coding variants, either they come from human samples, animals, plants, or microorganisms. Panos has won multiple awards in international competitions organized by the CAGI community for the superior performance of the Evolutionary Action amongst the current state-of-the-art methods in the field.

Websites

Selected Publications

• Katsonis P, Lichtarge O. "A formal perturbation equation between genotype and phenotype determines the Evolutionary Action of protein-coding variations on fitness." ; Pubmed PMID: 25217195
• Katsonis P, Lichtarge O. "CAGI5: Objective performance assessments of predictions based on the Evolutionary Action equation." ; Pubmed PMID: 31317604
• Katsonis P, Lichtarge O. "Objective assessment of the evolutionary action equation for the fitness effect of missense mutations across CAGI-blinded contests." ; Pubmed PMID: 28544059
• Katsonis P, Koire A, Wilson SJ, Hsu TK, Lua RC, Wilkins AD, Lichtarge O. "Single nucleotide variations: biological impact and theoretical interpretation." ; Pubmed PMID: 25234433