Positions
- Professor
-
Medicine
Thrombosis
Baylor College of Medicine
Houston, TX, US
- Member
-
Dan L Duncan Comprehensive Cancer Center
Baylor College of Medicine
Houston, Texas, United States
- Research Health Scientist
-
RSL
Michael E. DeBakey VA Medical Center
Houston, Texas, United States
Addresses
- MEDVAMC (Lab)
-
2002 Holcombe Blvd.
Building 109
Houston, TX 77030
United States
(713) 794-7775
miguelc@bcm.edu
- MEDVAMC (Office)
-
2002 Holcombe Blvd.
Building 109
Houston, TX 77030
United States
(713) 794-7775
miguelc@bcm.edu
Education
- PhD from University Of Puerto Rico School Of Medicine, Rio Piedras, Pr
- 01/1989 - Rio Piedras, PR
- Biochemistry
- Postdoctoral Fellowship at Harvard Medical School
- 01/1994 - Boston, Massachusetts, United States
- Protein Biochemistry - Hematology
- BS from University Of Puerto Rico, Rio Piedras, Puerto Rico
- Rio Piedras, PR
- Chemistry
- Advanced Training from Brigham And Women's Hospital
- 01/1994 - Boston, MA, United States
Professional Interests
- Thrombosis, von Willebrand factor, platelet adhesion, DIC, extracellular hemoglobin, inflammation, vimentin, tranlational medicine
Websites
Department of Medicine - Division of Thrombosis Research
Selected Publications
- Nguyen TC, Cruz MA, Carcillo JA. "Thrombocytopenia-Associated Multiple Organ Failure and Acute Kidney Injury.." Crit Care Clin.. 2015 : Pubmed PMID: 26410136
- Da Q, Teruya M, Guchhait P, Teruya J, Olson JS, Cruz MA. "Free hemoglobin increases von Willebrand factor-mediated platelet adhesion in vitro: implications on circulatory devices.." Blood. 2015 : Pubmed PMID: 26307534
- Nguyen, TC, Gushiken, F, Correa, JI, Dong, J-F, Dasgupta, SK, Thiagarajan, P, Cruz, M.A. "A recombinant fragment of von Willebrand factor reduces fibrin-rich microthrombi formation in mice with endotoxemia.." Thromb Res.. 2015 May ; 135 : Pubmed PMID: 25769494
- Qi Da, Molly Behymer, Juliana I. Correa, K. Vinod Vijayan, and Miguel A. Cruz. "Platelet adhesion involves a novel interaction between vimentin and von Willebrand factor under high shear stress.." Blood. 2014 123 : Pubmed PMID: 24642750
- Auton M, Sowa KE, Behymer M, Cruz MA "N-terminal Flanking Region of A1 Domain in von Willebrand Factor Stabilizes Structure of A1A2A3 Complex and Modulates Platelet Activation under Shear Stress.." J. Biol. Chem.. 2012 April 27; 287 (18): 14579-85. Pubmed PMID: 22431729
- Auton M, Sowa KE, Smith SM, Sedlák E, Vijayan KV, Cruz MA "Destabilization of the A1 domain in von Willebrand factor dissociates the A1A2A3 tri-domain and provokes spontaneous binding to glycoprotein Ibalpha and platelet activation under shear stress.." J. Biol. Chem.. 2010 July 23; 285 (30): 22831-9. Pubmed PMID: 20498367
Memberships
- International Society of Hemostasis and Thrombosis
Intellectual Property
- Product Patent #7879793 (Approved)
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