Positions
- Assistant Professor
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Department of Neuroscience, Huffington Center on Aging
Baylor College of Medicine
Houston, TX US
- CPRIT Scholar
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Cancer Prevention Research Institute of Texas
- Member
-
Dan L Duncan Comprehensive Cancer Center
Baylor College of Medicine
Houston, Texas United States
Education
- PhD from Washington University School of Medicine
- St. Louis, Missouri United States
- Postdoctoral Fellowship at Harvard
- Cambridge, Massachusetts United States
- BS from the University of Idaho
- Moscow, Idaho United States
- Summa Cum Laude, Biochemistry and Microbiology
- BA from the University of Idaho
- Moscow, United States
- Summa Cum Laude, English
Professional Interests
- Discovery of new neural development molecules and pathways.
- Development of nanoscopic imaging tools and techniques for circuit analysis.
- Novel genetic models of human neural diseases
- Computational approaches to circuit mapping.
Professional Statement
Neurons and glia form the road map that defines who we are and what we experience. We seek to understand how this road map is established and why it often fails in disease and old age. To find these answers, we focus our studies on discovering molecules important in determining neural identity and proper connectivity. Disruptions in this connectivity are thought to underlie many of the physiological changes that accompany normal neural aging as well as disease. Thus, we also study how cell identity and wiring change in neural diseases, such as cancer.Websites
Selected Publications
- Samuel MA, Voinescu PE, Lilley BN, de Cabo R, Foretz M, Viollet B, Pawlyk B, Sandberg MA, Vavvas DG, Sanes JR. "LKB1 and AMPK regulate synaptic remodeling in old age.." Nat Neurosci. September 17; : 1190-7. Pubmed PMID: 25086610
- Samuel MA, Valdez G, Tapia JC, Lichtman JW, Sanes JR. "Agrin and synaptic laminin are required to maintain adult neuromuscular junctions.." : Pubmed PMID: 23056392
- Samuel MA, Zhang Y, Meister M, Sanes JR. "Age-related alterations in neurons of the mouse retina.." J Neurosci.. : Pubmed PMID: 22049445
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