Meenakshi Anurag

Assistant Professor

Email

meenakshi.anurag@bcm.edu

Positions

Assistant Professor: Department of Medicine
Baylor College of Medicine
Houston, TX

Addresses

Baylor College of Medicine, 1 Baylor Plaza, BCM-Jewish Institute for Research (Lab)
: Room 645D,
Houston, TX 77030
United States
Phone: (713) 798-4298

Education

PhD from Institute of Genomics & Integrative Biology: 10/2014 - New Delhi, Delhi India

Postdoctoral Fellowship at Baylor College of Medicine: Houston

Professional Interests

Cancer multi-omics analysis
Immune informatics
Breast cancer

Professional Statement

The primary goal of my research is to improve disease diagnosis, treatment and survival by precision data science.
Since my PhD in Bioinformatics, have 7+ years of bioinformatics and data science experience in Cancer research. Cancer is a diverse and heterogeneous disease, hence one therapy will not be uniformly beneficial to all patients. I am also working on rare cancers like Male breast cancer. To dissect the molecular level heterogeneity of these tumors, we employ multi-omics and big data analysis on patient’s next generation sequencing and proteomics data. I implement bioinformatics to understand the role of mutations, structural variations, gene expressions, copy number variations, proteomics and genomic aberrations in promoting cancer.
In the past, I have shown role of DNA damage repair defects as a new class of endocrine treatment resistance driver in breast cancer. Exploring the cause and effect relationship further, we are trying to understanding the contribution of immune-checkpoint and other immune-tolerance factors in therapeutic resistant and advancement of estrogen-receptor positive disease. This warrants for integration of patient genome, transcriptome and metabolome with clinical data.