Email

marinam@bcm.edu

Positions

Instructor

Medicine-Thrombosis
Center for Translational Research on Inflammatory Diseases (CTRID)
Baylor College of Medicine
Houston, TX, US
The Role of von Willebrand Factor in Traumatic Brain Injury

Addresses

Center for Translational Research on Inflammatory Diseases (CTRID) (Lab)

Michael E. DeBakey VA Medical Center
2002 Holcombe Blvd. B. 109-146
Houston, TX, 77030
United States

Education

BS from University of Puerto Rico

05/2008 - Humacao, Puerto Rico, United States Minor Outlying Islands

Biology with minor in Microbiology

PhD from University of Puerto Rico-Medical Sciences Campus

08/2016 - San Juan, Puerto Rico, United States Minor Outlying Islands

Biochemistry and Molecular Biology

Honors & Awards

PDA Professional Career Committee Chair

Baylor College of Medicine (02/2021)

Websites

Professional Development

All of Us Faculty Summit

Course (Participant, 2023)

Fundamentals of SDOH Training

Course (Presenter, 2024)

Selected Publications

• Christian Valladolid, Marina Martinez-Vargas, Nitin Sekhar, Fong Lam, Cameron Brown, Timothy Palzkill, Alexander Tischer, Mathew Auton, K. Vinod Vijayan, Rolando E. Rumbaut, Trung C. Nguyen, and Miguel A. Cruz. " Modulating the rate of fibrin formation and clot structure attenuates microvascular thrombosis in systemic inflammation. " Blood Advances. 2020 Jan 15; 4 (7) : 1340-1349.
  Pubmed PMID: 7160269.
• Alexander Tischer; Maria A Brehm; Venkata R Machha; Laurie Moon-Tasson; Linda M Benson; Katelynn J Nelton; Rachel Leger; Tobias Obser; Marina Martinez-Vargas; Steven T Whitten; Dong Chen; Rajiv K Pruthi; Robert Bergen III; Miguel A Cruz; Matthew Auton. " Evidence for the Misfolding of the A1 Domain within Multimeric von Willebrand Factor in Type 2 von Willebrand Disease. " JMB. 2020 Jan 17; 432 (2) : 305-323.
  Pubmed PMID: 31628947.
• José A González-Feliciano, Marimar Hernández-Pérez, Luis A Estrella, Daisy D Colón-López, Armando López, Marina Martínez, Kirla R Maurás-Rivera, Clarivel Lasalde, Daviana Martínez, Félix Araujo-Pérez, Carlos I González. " The Role of HuR in the Post-Transcriptional Regulation of Interleukin-3 in T Cells. " Plos One. 2014 Mar 21; 9 (3)
  Pubmed PMID: 24658545.
• Lisandro Cunci, Marina Martinez Vargas, Roman Cunci, Ramon Gomez-Moreno, Ivan Perez, Abel Baerga-Ortiz, Carlos I Gonzalez, Carlos R Cabrera. " Real-Time Detection of Telomerase Activity in Cancer Cells using a Label-Free Electrochemical Impedimetric Biosensing Microchip. " RSC Adv.. 2014 Oct 15; 4 (94) : 52357-52365.
  Pubmed PMID: 25598969.
• Tripta Gupta, Yaqoob M Syed, Andrew A Revis, Samantha A Miller, Marina Martinez, Kellen A Cohn, Michael R Demeyer, Kevin Y Patel, Weronika J Brzezinska, Justin S Rhodes. " Acute effects of acamprosate and MPEP on ethanol Drinking-in-the-Dark in male C57BL/6J mice. " Alcohol Clin Exp Res.. 2008 Nov ; 32 (11) : 1992-8.
  Pubmed PMID: 18782337.
• Lisa S Brubaker, Arun Saini, Trung C Nguyen, Marina Martinez-Vargas, Fong W Lam, Qizhi Yao, Michele M Loor, Todd K Rosengart, Miguel A Cruz. " Aberrant Fibrin Clot Structure Visualized Ex Vivo in Critically Ill Patients With Severe Acute Respiratory Syndrome Coronavirus 2 Infection " Crit Care Med. ;
  Pubmed PMID: 35170535.
• Martinez-Vargas M, Cebula A, Brubaker LS, Seshadri N, Lam FW, Loor M, Rosengart TK, Yee A, Rumbaut RE, Cruz MA.. " A novel interaction between extracellular vimentin and fibrinogen in fibrin formation. " ;
  Pubmed PMID: 36495717.
• Pediatric Swine Model of Methicillin-Resistant Staphylococcus aureus Sepsis-Induced Coagulopathy, Disseminated Microvascular Thrombosis, and Organ Injuries. " ;
  Pubmed PMID: 37255626.
• Marina Martinez-Vargas, Arun Saini, Subhashree Pradhan, Luis Gardea, Barbara Stoll, Inka C Didelija, K Vinod Vijayan, Trung C Nguyen, Miguel A Cruz. " Elevated level of extracellular vimentin is associated with an increased fibrin formation potential in sepsis: ex vivo swine study " Intensive Care Med Exp.. 2024 Aug 29; 12 (1)
  Pubmed PMID: 39207603.
• Marina Martinez-Vargas, Justin Courson, Luis Gardea, Mehmet Sen, Andrew Yee, Rolando Rumbaut, Miguel A Cruz. " The impact of von Willebrand factor on fibrin formation and structure unveiled with type 3 von Willebrand disease plasma " Blood Coagul Fibrinolysis. 2024 Jul 1; 35 (5) : 256-264.
  Pubmed PMID: 38973517.

Show 6 more publications

Memberships

Hemostasis and Thrombosis Research Society

Member (07/2024)

Funding

Diversity Supplement

NIH/NHLBI

Collaborative Research Training in Thrombosis and Inflammation

(06/06/2019 - 05/31/2022)

NIH/NHLBI

T32 Postdoctoral Training Fellowship

VA Seed Grant

$40,000.00   (10/01/2023 - 09/30/2024)

Grant funding from Veteran Affairs

Intellectual Property

Electrochemical impedimetric biosensing microchip for real time telomerase activity detection

Product Patent #US-11340189-B2 (Approved)

Co Inventors: Cabrera Carlos Raúl, Cunei Lisandro Federico, González Carlos I

Skills

Protein Purification

Cell Culture

Molecular and Biochemical Approaches

Mice Genotyping

Histology

Languages

Spanish