Positions
- Professor Emeritus
-
Pharmacology and Chemical Biology
Baylor College of Medicine
Houston, United States
Addresses
- BCM-Michael DeBakey Center (Office)
-
Room: BCMM-220.17
Houston, TX 77030
United States
Education
- Advanced Training from Catholic University Of America
- 01/1991 - Washington, DC United States
- Advanced Training from Baylor College Of Medicine
- 01/1970 - Houston, TX United States
- Ph.D. from University Of Illinois, Urbana-Champaign
- 01/1970 - Urbana, IL United States
- B.A. from Depauw University
- 01/1965 - Greencastle, IN United States
Websites
VIICTR Research Database
Selected Publications
- Yeoman LC, Olson MO, Sugano N, Jordan JJ, Taylor DW, Starbuck WC, Busch H "Amino acid sequence of the center of the arginine-lysine-rich histone from calf thymus. The total sequence.." J. Biol. Chem.. 1972 Oct 10;247(19):6018-23. Pubmed PMID: 4568599
- Sugano N, Olson MO, Yeoman LC, Johnson BR, Taylor CW, Starbuck WC, Busch H "Amino acid sequence of the COOH-terminal portion of the arginine-lysine-rich histone of calf thymus.." J. Biol. Chem.. 1972 Jun 10;247(11):3589-91. Pubmed PMID: 4555425
- Yeoman LC "An autocrine model for cell- and matrix-associated fibroblast growth factor.." Oncol. Res.. 1993;5(12):489-99. Pubmed PMID: 8086671
- Gross ME, Zorbas MA, Danels YJ, Garcia R, Gallick GE, Olive M, Brattain MG, Boman BM, Yeoman LC "Cellular growth response to epidermal growth factor in colon carcinoma cells with an amplified epidermal growth factor receptor derived from a familial adenomatous polyposis patient.." Cancer Res.. 1991 Mar 1;51(5):1452-9. Pubmed PMID: 1847663
- Lischwe MA, Cook RG, Ahn YS, Yeoman LC, Busch H "Clustering of glycine and NG,NG-dimethylarginine in nucleolar protein C23.." Biochemistry. 1985 Oct 22;24(22):6025-8. Pubmed PMID: 4084504
- Wan CW, McKnight MK, Brattain DE, Brattain MG, Yeoman LC "Different epidermal growth factor growth responses and receptor levels in human colon carcinoma cell lines.." Cancer Lett.. 1988 Dec 1;43(41276):139-43. Pubmed PMID: 3264518
- Novotny-Smith CL, Zorbas MA, Mcisaac AM, Irimura T, Boman BM, Yeoman LC, Gallick GE "Down-modulation of epidermal growth factor receptor accompanies TNF-induced differentiation of the DiFi human adenocarcinoma cell line toward a goblet-like phenotype.." J. Cell. Physiol.. 1993 Nov;157(2):253-62. Pubmed PMID: 8227158
- Bhattycharyya L, Dabbah R, Hauck W, Sheinin E, Yeoman L, Williams R "Equivalence studies for complex active ingredients and dosage forms.." AAPS J. 2005;7(4):E786-812. Pubmed PMID: 16594632
- Zorbas MA, Yeoman LC "Growth control in a human colon carcinoma cell line mediated by cell-associated transforming growth factor-alpha (TGF alpha).." Exp. Cell Res.. 1993 May;206(1):49-57. Pubmed PMID: 8482359
- Brattain MG, Levine AE, Chakrabarty S, Yeoman LC, Willson JK, Long B "Heterogeneity of human colon carcinoma.." Cancer Metastasis Rev.. 1984;3(3):177-91. Pubmed PMID: 6437669
- Olson MO, Sugano N, Yeoman LC, Johnson BR, Jordan J, Taylor CW, Starbuck WC, Busch H "Homology of the amino terminal sequences of the AL and GAR calf thymus histones.." Physiol. Chem. Phys.. 1972;4(1):41553. Pubmed PMID: 4667695
- New BA, Yeoman LC "Identification of basic fibroblast growth factor sensitivity and receptor and ligand expression in human colon tumor cell lines.." J. Cell. Physiol.. 1992 Feb;150(2):320-6. Pubmed PMID: 1310324
- Yeoman LC, Sebastian RV, Richards BF "Inclusion of allied health students in a problem-based learning course.." Acad Med. 1998 May;73(5):607-8. Pubmed PMID: 9643929
- Andrus PL, Fasser CE, Yeoman L "Interdisciplinary learning in pharmacology: analysis of M.D. and P.A. student performance.." J Med Educ. 1981 Sep;56(9):757-61. Pubmed PMID: 6115945
- Yeoman LC, Hager LP "Isolation of a heme crevice peptide from affinity-labeled horseradish peroxidase.." Biochem. Biophys. Res. Commun.. 1980 Dec 16;97(3):1233-40. Pubmed PMID: 7470149
- Yeoman LC, Danels YJ, Lynch MJ "Lipofectin enhances cellular uptake of antisense DNA while inhibiting tumor cell growth.." Antisense Res. Dev.. 1992;2(1):51-9. Pubmed PMID: 1422086
- Bennett CF, Yeoman LC "Microinjected glutathione S-transferase Yb subunits translocate to the cell nucleus.." Biochem. J.. 1987 Oct 1;247(1):109-12. Pubmed PMID: 3689337
- Brattain MG, Willson JK, Long BH, Chakrabarty S, Yeoman LC, Stringfellow DA "Overcoming mitomycin C resistance with semisynthetic derivatives.." Prog. Clin. Biol. Res.. 1986;223:63-79. Pubmed PMID: 3101070
- Taylor CW, Kim YS, Childress-Fields KE, Yeoman LC "Sensitivity of nuclear c-myc levels and induction to differentiation-inducing agents in human colon tumor cell lines.." Cancer Lett.. 1992 Feb 29;62(2):95-105. Pubmed PMID: 1540946
- Yeoman LC, Wan CW, Zorbas MA "Transferrin and insulin enhance human colon tumor cell growth by differentiation class specific mechanisms.." Oncol. Res.. 1996;8(41463):273-9. Pubmed PMID: 8938790
- Untawale S, Zorbas MA, Hodgson CP, Coffey RJ, Gallick GE, North SM, Wildrick DM, Olive M, Blick M, Yeoman LC "Transforming growth factor-alpha production and autoinduction in a colorectal carcinoma cell line (DiFi) with an amplified epidermal growth factor receptor gene.." Cancer Res.. 1993 Apr 1;53(7):1630-6. Pubmed PMID: 8453634
- Williams RL "US Pharmacopeia Council of Experts 2005-2010: work plans, new revision approaches, and other enhancements.." AAPS J. 2006;8(4):E661-4. Pubmed PMID: 17285738
- Yeoman LC, Jordan JJ, Busch RK, Taylor CW, Savage HE, Busch H "A fetal protein in chromatin of Novikoff hepatoma and Walker 256 carcinosarcoma tumors that is absent from normal and regenerating rat liver.." Proc. Natl. Acad. Sci. U.S.A.. 1976 Sep;73(9):3258-62. Pubmed PMID: 184470
- Bennett FC, Yeoman LC "An improved procedure for the 'dot immunobinding' analysis of hybridoma supernatants.." J. Immunol. Methods. 1983 Jul 15;61(2):201-7. Pubmed PMID: 6863946
- Bennett FC, Busch H, Lischwe MA, Yeoman LC "Antibodies to a nucleolar protein are localized in the nucleolus after red blood cell-mediated microinjection.." J. Cell Biol.. 1983 Nov;97(5):1566-72. Pubmed PMID: 6355122
- Busch H, Yeoman LC, Busch RK, Jordan JJ, Rao MS, Taylor CW, Wu BC "Antigenically active nonhistone chromatin proteins in cancer cells.." Cancer Res.. 1976 Sep;36(9):3399-408. Pubmed PMID: 184949
- Pasternak M, Debrunner PG, Depasquali G, Hager LP, Yeoman L "Application of I mossbauer effect to biological systems: studies with heme models.." Proc. Natl. Acad. Sci. U.S.A.. 1970 Aug;66(4):1142-9. Pubmed PMID: 16591848
- Huang KW, Moosic JP, Taylor CW, Lane M, Yeoman LC "Characterization and reactivity of a monoclonal antibody that recognizes a 76 kilodalton human colon tumor antigen.." Cancer Lett.. 1988 Mar;39(2):161-77. Pubmed PMID: 2452009
- Catino JJ, Yeoman LC, Mandel M, Busch H "Characterization of DNA binding protein from rat liver chromatin which decreases during growth.." Biochemistry. 1978 Mar 21;17(6):983-7. Pubmed PMID: 629956
- Moosic JP, Mosley AM, Huang K, Taylor CW, Yeoman LC "Characterization of two monoclonal antibodies that recognize high molecular weight colon antigens.." Cancer Lett.. 1989 Feb;44(2):127-36. Pubmed PMID: 2920372
- Goldberg AH, Yeoman LC, Busch H "Chromatin-associated glycoproteins of normal rat liver and Novikoff hepatoma ascites cells.." Cancer Res.. 1978 Apr;38(4):1052-6. Pubmed PMID: 205344
- Bennett FC, Yeoman LC "Co-localization of non-histone protein BA with U-snRNPs to the same regions of the cell nucleus.." Exp. Cell Res.. 1985 Apr;157(2):379-86. Pubmed PMID: 2579834
- Chakrabarty S, Taylor CW, Yeoman LC "Comparison of immunoelectrophoretic techniques for the analysis of cytosol antigens.." J. Immunol. Methods. 1981;43(3):301-11. Pubmed PMID: 7252169
- Cochran DL, Yeoman LC, Egle PM, Shelton KR "Comparison of the major polypeptides of the erythrocyte nuclear envelope.." J. Supramol. Struct.. 1979;10(4):405-18. Pubmed PMID: 513770
- Yeoman LC, Taylor CW, Jordan JJ, Busch H "Differences in chromatin proteins of growing and non-growing tissues.." Exp. Cell Res.. 1975 Mar 1;91(1):207-15. Pubmed PMID: 165944
- Yeoman LC, Seeber S, Taylor CW, Fernbach DJ, Falletta JM, Jordan JJ, Busch H "Differences in chromatin proteins of resting and growing human lymphocytes.." Exp. Cell Res.. 1976 Jun;100(1):47-55. Pubmed PMID: 1064554
- Davis FM, Busch RK, Yeoman LC, Busch H "Differences in nucleolar antigens of rat liver and Novikoff hepatoma ascites cells.." Cancer Res.. 1978 Jul;38(7):1906-15. Pubmed PMID: 77722
- Bremer JW, Busch H, Yeoman LC "Evidence for a species of nuclear actin distinct from cytoplasmic and muscles actins.." Biochemistry. 1981 Mar 31;20(7):2013-7. Pubmed PMID: 6894385
- Bennett FC, Rosenfeld BI, Huang CH, Yeoman LC "Evidence for two conformational forms of nonhistone protein BA which differ in their affinity for DNA.." Biochem. Biophys. Res. Commun.. 1982 Jan 29;104(2):649-56. Pubmed PMID: 7073705
- Levine AE, Hamilton DA, Yeoman LC, Busch H, Brattain MG "Identification of a tumor inhibitory factor in rat ascites fluid.." Biochem. Biophys. Res. Commun.. 1984 Feb 29;119(1):76-82. Pubmed PMID: 6704134
- Taylor CW, Chakrabarty S, Schauder KS, Yeoman LC "Identification of cytosolic antigens from GW-39 adenocarcinoma cells by crossed immunoelectrophoresis and immunofluorescence.." Immunol. Commun.. 1983;12(3):315-29. Pubmed PMID: 6350166
- Levine AE, McRae LJ, Hamilton DA, Brattain DE, Yeoman LC, Brattain MG "Identification of endogenous inhibitory growth factors from a human colon carcinoma cell line.." Cancer Res.. 1985 May;45(5):2248-54. Pubmed PMID: 3857117
- Taylor CW, Yeoman LC "Inhibition of colon tumor cell growth by 8-chloro-cAMP is dependent upon its conversion to 8-chloro-adenosine.." Anticancer Drugs. 1992 Oct;3(5):485-91. Pubmed PMID: 1450443
- James GT, Yeoman LC, Matsui S, Goldberg AH, Busch H "Isolation and characterization of nonhistone chromosomal protein C-14 which stimulates RNA synthesis.." Biochemistry. 1977 May 31;16(11):2384-9. Pubmed PMID: 193558
- Goldknopf IL, Taylor CW, Baum RM, Yeoman LC, Olson MO, Prestayko AW, Busch H "Isolation and characterization of protein A24, a histone-like" non-histone chromosomal protein."." J. Biol. Chem.. 1975 Sep 25;250(18):7182-7. Pubmed PMID: 1165239
- Busch H, Choi YC, Daskal I, Inagaki A, Olson MO, Reddy R, Ro-Choi TS, Shibata H, Yeoman LC "Isolation and composition of nuclei and nucleoli.." Acta Endocrinol Suppl (Copenh). 1972;168:35-66. Pubmed PMID: 4562656
- Chakrabarty S, Taylor CW, Yeoman LC "Isolation and partial characterization of a 700 kilodalton human colon carcinoma associated antigen.." Cancer Biochem. Biophys.. 1983;6(4):249-59. Pubmed PMID: 6616431
- Taylor CW, Yeoman LC, Woolf LM, Busch H "Isolation of a 70 000 molecular weight antigen of the Novikoff hepatoma.." Biochemistry. 1979 Sep 18;18(19):4049-54. Pubmed PMID: 114207
- Busch GI, Yeoman LC, Taylor CW, Busch H "Modified two-dimensional polyacrylamide gel electrophoresis systems for higher molecular weight nonhistone chromatin proteins from normal rat liver and Novikoff hepatoma ascites cells.." Physiol. Chem. Phys.. 1974;6(1):41284. Pubmed PMID: 4134968
- Bennett CF, Spector DL, Yeoman LC "Nonhistone protein BA is a glutathione S-transferase localized to interchromatinic regions of the cell nucleus.." J. Cell Biol.. 1986 Feb;102(2):600-9. Pubmed PMID: 2935545
- Michalik J, Yeoman LC, Busch H "Nucleolar localization of protein B23 (37/5.1) by immunocytochemical techniques.." Life Sci.. 1981 Mar 23;28(12):1371-9. Pubmed PMID: 7017325
- Lischwe MA, Roberts KD, Yeoman LC, Busch H "Nucleolar specific acidic phosphoprotein C23 is highly methylated.." J. Biol. Chem.. 1982 Dec 25;257(24):14600-2. Pubmed PMID: 7174653
- Taylor CW, Brattain MG, Yeoman LC "Occurrence of cytosolic protein and phosphoprotein changes in human colon tumor cells with the development of resistance to mitomycin C.." Cancer Res.. 1985 Sep;45(9):4422-7. Pubmed PMID: 3928156
- Lischwe MA, Ochs RL, Reddy R, Cook RG, Yeoman LC, Tan EM, Reichlin M, Busch H "Purification and partial characterization of a nucleolar scleroderma antigen (Mr = 34,000; pI, 8.5) rich in NG,NG-dimethylarginine.." J. Biol. Chem.. 1985 Nov 15;260(26):14304-10. Pubmed PMID: 2414294
- Yeoman LC, Bremer JW "Purification and properties of a 90-kDa nuclear actin-binding protein.." Proc. Soc. Exp. Biol. Med.. 1986 Apr;181(4):479-85. Pubmed PMID: 3952079
- Taylor CW, Yeoman LC, Jordan JJ, Goldknopf IL, Busch H "Quantitative analysis of the distribution of 3H-leucine in acid soluble chromatin proteins of Noviknoff hepatoma cells separated by two-dimensional polyacrylamide gel electrophoresis.." Physiol. Chem. Phys.. 1976;8(1):41345. Pubmed PMID: 183225
- Taylor CW, Brattain MG, Yeoman LC "Rate of growth and extent of differentiation reflected by cytoplasmic proteins and antigens of human colon tumor cell lines.." Cancer Res.. 1984 Mar;44(3):1200-5. Pubmed PMID: 6362859
- Smetana K, Ochs RL, Busch RK, Yeoman LC, Busch H "Studies on satellite nucleoli in rat hepatocytes and Novikoff hepatoma cells.." Cell Tissue Res.. 1987 Jul;249(1):235-9. Pubmed PMID: 3621293
- Catino JJ, Busch H, Daskal Y, Yeoman LC "Subcellular localization of DNA-binding protein BA by immunofluorescence and immunoelectron microscopy.." J. Cell Biol.. 1979 Nov;83(2):462-7. Pubmed PMID: 227916
- Taylor CW, Yeoman LC, Busch H "The isolation of nuclei with citric acid and the analysis of proteins by two-dimensional polyacrylamide gel electrophoresis.." Methods Cell Biol.. 1975;9:349-76. Pubmed PMID: 166288
- Nalty TJ, Yeoman LC "Transfer of proteins from acrylamide gels to nitrocellulose paper after silver stain detection.." J. Immunol. Methods. 1988 Feb 24;107(1):143-9. Pubmed PMID: 2449504
- Taylor CW, Yeoman LC, Daskal I, Busch H "Two-dimensional electrophoresis of proteins of citric acid nuclei prepared with aid of a Tissumizer.." Exp. Cell Res.. 1973 Nov;82(1):215-26. Pubmed PMID: 4356488
- Yeoman LC, Taylor CW, Busch H "Two-dimensional gel electrophoresis of acid-extractable nuclear proteins of regenerating and thioacetamide-treated rat liver, Morris 9618a hepatoma, and Walker 256 carcinosarcoma.." Cancer Res.. 1974 Feb;34(2):424-8. Pubmed PMID: 4359383
- Yeoman LC, Taylor CW, Woolf LM, Busch H "Two-dimensional polyacrylamide gel analysis on nuclear proteins from human tumor cell lines.." Cancer. 1978 Aug;42(2):474-82. Pubmed PMID: 567094
- Yeoman LC, Taylor CW, Busch H "Two-dimensional polyacrylamide gel electrophoresis of acid extractable nuclear proteins of normal rat liver and Novikoff hepatoma ascites cells.." Biochem. Biophys. Res. Commun.. 1973 Apr 16;51(4):956-66. Pubmed PMID: 4349999
- Yeoman LC, Taylor CW, Jordan JJ, Busch H "Two-dimensional polyacrylamide gel electrophoresis of chromatin proteins of normal rat liver and Novikoff hepatoma ascites cells.." Biochem. Biophys. Res. Commun.. 1973 Aug 21;53(4):1067-76. Pubmed PMID: 4356049
- Nalty TJ, Taylor CW, Yeoman LC "Variation in cytosolic protein expression between human colon tumors that differ with regard to differentiation class.." Clin. Chem.. 1988 Jan;34(1):71-5. Pubmed PMID: 2448066
Intellectual Property
- Product Patent #4,916,0565 (Approved)
Skills
- pharmacology, medical education, problem-based learning, cancer prevention
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