Email

Positions

Professor

Pediatrics-Hema & Oncology
Baylor College of Medicine
Houston, Texas, United States

Member

Dan L Duncan Comprehensive Cancer Center
Baylor College of Medicine
Houston, Texas, United States

Addresses

Texas Children's Hospital, Clinical Care Center (Clinic)

6701 Fannin St
14th floor
Houston, TX, 77030
United States
Phone: (832) 822-4242

Websites

Selected Publications

• Horton TM, Pati D, Plon SE, Thompson PA, Bomgaars LR, Adamson PC, Ingle AM, Wright J, Brockman AH, Paton M, Blaney SM. " A phase 1 study of the proteasome inhibitor bortezomib in pediatric patients with refractory leukemia: a Children's Oncology Group study. " Clin. Cancer Res.. 2007 Mar 1; 13 (5) : 1516-22.
  Pubmed PMID: 17332297.
• Bomgaars L, Kerr J, Berg S, Kuttesch J, Klenke R, Blaney SM. " A phase I study of irinotecan administered on a weekly schedule in pediatric patients. " Pediatr Blood Cancer. 2006 Jan ; 46 (1) : 50-5.
  Pubmed PMID: 15768380.
• Bussel JB, Buchanan GR, Nugent DJ, Gnarra DJ, Bomgaars LR, Blanchette VS, Wang YM, Nie K, Jun S. " A randomized, double-blind study of romiplostim to determine its safety and efficacy in children with immune thrombocytopenia. " Blood. 2011 Jul 7; 118 (1) : 28-36.
  Pubmed PMID: 21502541.
• Richard AA, Kim S, Moffett BS, Bomgaars L, Mahoney D, Yee DL. " Comparison of anti-xa levels in obese and non-obese pediatric patients receiving treatment doses of enoxaparin. " J. Pediatr.. 2013 Feb ; 162 (2) : 293-6.
  Pubmed PMID: 22959138.
• Bomgaars L, Carberry K, Fraser C, West A, Teruya J. " Development of Factor V and Thrombin Inhibitors in Children Following Bovine Thrombin Exposure during Cardiac Surgery: A Report of Three Cases. " Congenit Heart Dis. 2010 May ; 5 (3) : 303-8.
  Pubmed PMID: 20576051.
• Krull KR, Brouwers P, Jain N, Zhang L, Bomgaars L, Dreyer Z, Mahoney D, Bottomley S, Okcu MF. " Folate pathway genetic polymorphisms are related to attention disorders in childhood leukemia survivors. " J. Pediatr.. 2008 Jan ; 152 (1) : 101-5.
  Pubmed PMID: 18154909.
• Thompson PA, Rosner GL, Matthay KK, Moore TB, Bomgaars LR, Ellis KJ, Renbarger J, Berg SL. " Impact of body composition on pharmacokinetics of doxorubicin in children: a Glaser Pediatric Research Network study. " Cancer Chemother. Pharmacol.. 2009 Jul ; 64 (2) : 243-51.
  Pubmed PMID: 19020877.
• Yee DL, Dinu BR, Sun CW, Edwards RM, Justino H, Teruya J, Bray PF, Bomgaars L. " Low prevalence and assay discordance of aspirin resistance" in children." " Pediatr Blood Cancer. 2008 Jul ; 51 (1) : 86-92.
  Pubmed PMID: 18253960.
• Murray JC, Bomgaars LR, Carcamo B, Mahoney DH. " Lymphoid malignancies following Kawasaki disease. " Am. J. Hematol.. 1995 Dec ; 50 (4) : 299-300.
  Pubmed PMID: 7485107.
• Blake MJ, Gaedigk A, Pearce RE, Bomgaars LR, Christensen ML, Stowe C, James LP, Wilson JT, Kearns GL, Leeder JS. " Ontogeny of dextromethorphan O- and N-demethylation in the first year of life. " Clin. Pharmacol. Ther.. 2007 Apr ; 81 (4) : 510-6.
  Pubmed PMID: 17301735.
• Thompson PA, Murry DJ, Rosner GL, Lunagomez S, Blaney SM, Berg SL, Camitta BM, Dreyer ZE, Bomgaars LR. " Methotrexate pharmacokinetics in infants with acute lymphoblastic leukemia. " Cancer Chemother. Pharmacol.. 2007 May ; 59 (6) : 847-53.
  Pubmed PMID: 17136402.
• Thornburg CD, Jones E, Bomgaars L, Gage BF. " Pediatric warfarin practice and pharmacogenetic testing. " Thromb. Res.. 2010 Aug ; 126 (2) : e144-6.
  Pubmed PMID: 20097410.
• Bomgaars L, McLeod HL. " Pharmacogenetics and pediatric cancer. " Cancer J. ; 11 (4) : 314-23.
  Pubmed PMID: 16197721.
• Lacayo NJ, Lum BL, Becton DL, Weinstein H, Ravindranath Y, Chang MN, Bomgaars L, Lauer SJ, Sikic BI, Dahl GV. " Pharmacokinetic interactions of cyclosporine with etoposide and mitoxantrone in children with acute myeloid leukemia. " Leukemia. 2002 May ; 16 (5) : 920-7.
  Pubmed PMID: 11986955.
• Berg S, Serabe B, Aleksic A, Bomgaars L, McGuffey L, Dauser R, Durfee J, Nuchtern J, Blaney S. " Pharmacokinetics and cerebrospinal fluid penetration of phenylacetate and phenylbutyrate in the nonhuman primate. " Cancer Chemother. Pharmacol.. 2001 May ; 47 (5) : 385-90.
  Pubmed PMID: 11391852.
• Sáez-Llorens X, Yogev R, Arguedas A, Rodriguez A, Spigarelli MG, De León Castrejón T, Bomgaars L, Roberts M, Abrams B, Zhou W, Looby M, Kaiser G, Hamed K. " Pharmacokinetics and safety of famciclovir in children with herpes simplex or varicella-zoster virus infection. " Antimicrob. Agents Chemother.. 2009 May ; 53 (5) : 1912-20.
  Pubmed PMID: 19273678.
• Thompson PA, Gupta M, Rosner GL, Yu A, Barrett J, Bomgaars L, Bernstein ML, Blaney SM, Mondick J. " Pharmacokinetics of irinotecan and its metabolites in pediatric cancer patients: a report from the children's oncology group. " Cancer Chemother. Pharmacol.. 2008 Nov ; 62 (6) : 1027-37.
  Pubmed PMID: 18278496.
• Chintagumpala M, Blaney SM, Bomgaars LR, Aleksic A, Kuttesch JF, Klenke RA, Berg SL. " Phase I and pharmacokinetic study of thalidomide with carboplatin in children with cancer. " J. Clin. Oncol.. 2004 Nov 1; 22 (21) : 4394-400.
  Pubmed PMID: 15514381.
• Bernardi RJ, Bomgaars L, Fox E, Balis FM, Egorin MJ, Lagattuta TF, Aikin A, Whitcomb P, Renbarger J, Lieberman FS, Berg SL, Blaney SM. " Phase I clinical trial of intrathecal gemcitabine in patients with neoplastic meningitis. " Cancer Chemother. Pharmacol.. 2008 Jul ; 62 (2) : 355-61.
  Pubmed PMID: 17909804.
• Bomgaars L, Geyer JR, Franklin J, Dahl G, Park J, Winick NJ, Klenke R, Berg SL, Blaney SM. " Phase I trial of intrathecal liposomal cytarabine in children with neoplastic meningitis. " J. Clin. Oncol.. 2004 Oct 1; 22 (19) : 3916-21.
  Pubmed PMID: 15459213.
• Gururangan S, Petros WP, Poussaint TY, Hancock ML, Phillips PC, Friedman HS, Bomgaars L, Blaney SM, Kun LE, Boyett JM. " Phase I trial of intrathecal spartaject busulfan in children with neoplastic meningitis: a Pediatric Brain Tumor Consortium Study (PBTC-004). " Clin. Cancer Res.. 2006 Mar 1; 12 (5) : 1540-6.
  Pubmed PMID: 16533779.
• Bomgaars LR, Megason GC, Pullen J, Langevin AM, Dale Weitman S, Hershon L, Kuhn JG, Bernstein M, Blaney SM. " Phase I trial of irofulven (MGI 114) in pediatric patients with solid tumors. " Pediatr Blood Cancer. 2006 Aug ; 47 (2) : 163-8.
  Pubmed PMID: 16317728.
• Jeha S, Gaynon PS, Razzouk BI, Franklin J, Kadota R, Shen V, Luchtman-Jones L, Rytting M, Bomgaars LR, Rheingold S, Ritchey K, Albano E, Arceci RJ, Goldman S, Griffin T, Altman A, Gordon B, Steinherz L, Weitman S, Steinherz P. " Phase II study of clofarabine in pediatric patients with refractory or relapsed acute lymphoblastic leukemia. " J. Clin. Oncol.. 2006 Apr 20; 24 (12) : 1917-23.
  Pubmed PMID: 16622268.
• Jeha S, Razzouk B, Rytting M, Rheingold S, Albano E, Kadota R, Luchtman-Jones L, Bomgaars L, Gaynon P, Goldman S, Ritchey K, Arceci R, Altman A, Stine K, Steinherz L, Steinherz P. " Phase II study of clofarabine in pediatric patients with refractory or relapsed acute myeloid leukemia. " J. Clin. Oncol.. 2009 Sep 10; 27 (26) : 4392-7.
  Pubmed PMID: 19652076.
• Bomgaars LR, Bernstein M, Krailo M, Kadota R, Das S, Chen Z, Adamson PC, Blaney SM. " Phase II trial of irinotecan in children with refractory solid tumors: a Children's Oncology Group Study. " J. Clin. Oncol.. 2007 Oct 10; 25 (29) : 4622-7.
  Pubmed PMID: 17925558.
• Klaassen RJ, Mathias SD, Buchanan G, Bussel J, Deuson R, Young NL, Collier A, Bomgaars L, Blanchette V. " Pilot study of the effect of romiplostim on child health-related quality of life (HRQoL) and parental burden in immune thrombocytopenia (ITP). " Pediatr Blood Cancer. 2012 Mar ; 58 (3) : 395-8.
  Pubmed PMID: 21910213.
• Evans WE, Hon YY, Bomgaars L, Coutre S, Holdsworth M, Janco R, Kalwinsky D, Keller F, Khatib Z, Margolin J, Murray J, Quinn J, Ravindranath Y, Ritchey K, Roberts W, Rogers ZR, Schiff D, Steuber C, Tucci F, Kornegay N, Krynetski EY, Relling MV. " Preponderance of thiopurine S-methyltransferase deficiency and heterozygosity among patients intolerant to mercaptopurine or azathioprine. " J. Clin. Oncol.. 2001 Apr 15; 19 (8) : 2293-301.
  Pubmed PMID: 11304783.
• Fraser CD, Jaquiss RD, Rosenthal DN, Humpl T, Canter CE, Blackstone EH, Naftel DC, Ichord RN, Bomgaars L, Tweddell JS, Massicotte MP, Turrentine MW, Cohen GA, Devaney EJ, Pearce FB, Carberry KE, Kroslowitz R, Almond CS. " Prospective trial of a pediatric ventricular assist device. " N. Engl. J. Med.. 2012 Aug 9; 367 (6) : 532-41.
  Pubmed PMID: 22873533.
• Moffett BS, Ung M, Bomgaars L. " Risk factors for elevated INR values during warfarin therapy in hospitalized pediatric patients. " Pediatr Blood Cancer. 2012 Jun ; 58 (6) : 941-4.
  Pubmed PMID: 22069087.
• Bomgaars L, Berg SL, Blaney SM. " The development of camptothecin analogs in childhood cancers. " Oncologist. 2001 ; 6 (6) : 506-16.
  Pubmed PMID: 11743213.
• Bomgaars L, Gunawardena S, Kelley SE, Ramu A. " The inactivation of doxorubicin by long ultraviolet light. " Cancer Chemother. Pharmacol.. 1997 ; 40 (6) : 506-12.
  Pubmed PMID: 9332465.
• Raman VS, Mason KJ, Rodriguez LM, Hassan K, Yu X, Bomgaars L, Heptulla RA. " The role of adjunctive exenatide therapy in pediatric type 1 diabetes. " Diabetes Care. 2010 Jun ; 33 (6) : 1294-6.
  Pubmed PMID: 20332358.
• Heptulla RA, Rodriguez LM, Bomgaars L, Haymond MW. " The role of amylin and glucagon in the dampening of glycemic excursions in children with type 1 diabetes. " Diabetes. 2005 Apr ; 54 (4) : 1100-7.
  Pubmed PMID: 15793249.
• Bomgaars L, Thompson P, Berg S, Serabe B, Aleksic A, Blaney S. " Valacyclovir and acyclovir pharmacokinetics in immunocompromised children. " Pediatr Blood Cancer. 2008 Oct ; 51 (4) : 504-8.
  Pubmed PMID: 18561175.