Katherine Ellen Pendleton

Graduate Student

Email

katherine.pendleton@bcm.edu

Positions

Graduate Student: Molecular and Human Genetics
Baylor College of Medicine

Education

BS from Georgia Institute of Technology: 05/2018 - Atlanta, Georgia, United States; Biology: Health and Medical Sciences

Professional Statement

I am broadly interested in metabolic adaptations and the immune microenvironment in chemoresistant triple negative breast cancer (TNBC). My goal is to improve our understanding of TNBC on the genomic level and apply this knowledge into developing targeted therapeutics.

Websites

Echeverria Lab

Selected Publications

The MBCRC Advocate Researcher Program (MARP): connecting advocates and researchers as collaborative partners in cancer research " NPJ Breast Cancer. 2025 Jun 21;
Pubmed PMID: 40544177.
Xenomake: a pipeline for processing and sorting xenograft reads from spatial transcriptomic experiments " Bioinformatics. 2024 Oct 14;
Pubmed PMID: 39400332.
Rewiring of mitochondrial metabolism in therapy-resistant cancers: permanent and plastic adaptations " Frontiers in Cell and Developmental Biology. 2023 Sep 13;
Pubmed PMID: 37779896.
FOXP1 Haploinsufficiency Contributes to the Development of Congenital Diaphragmatic Hernia " Journal of Pediatric Genetics. 2023 Mar 28;
Pubmed PMID: 38567173.
SOX7 deficiency causes ventricular septal defects through its effects on endocardial-to-mesenchymal transition and the expression of Wnt4 and Bmp2 " Human Molecular Genetics. 2023 Mar 31;
Pubmed PMID: 37000005.
Mitochondrial structure and function adaptation in residual triple negative breast cancer cells surviving chemotherapy treatment " Oncogene. 2023 ;
Pubmed PMID: 36813854.
Aberrant extrafollicular B cells, immune dysfunction, myeloid inflammation and MyD88-mutant progenitors precede malignancy in Waldenstrom macroglobulinemia " Blood Cancer Discovery. 2021 Sep 1;
Pubmed PMID: 34778800.
Risk-associated alterations in marrow T cells in pediatric leukemia " JCI Insight. 2020 Jul 21; 5 (16)
Pubmed PMID: 32692727.
Early alterations in stem-like/marrow-resident T cells and innate and myeloid cells in preneoplastic gammopathy " JCI Insight. 2019 Jun 6; 4 (11)
Pubmed PMID: 31013254.
Differential effects of PD-L1 versus PD-1 blockade on myeloid inflammation in human cancer " JCI Insight. 2019 May 19; 5 (12)
Pubmed PMID: 32427579.

Funding

Ruth L. Kirschstein Predoctoral Individual National Research Service Award #F31CA275397: National Cancer Institute

T32 Predoctoral Training Grant #T32GM139534: National Institutes of Health

Predoctoral Training Grant: The Cullen Foundation