Katherine Yudeh King, M.D., Ph.D.
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Katherine Yudeh King, M.D., Ph.D.
Professor
Positions
- Professor
-
Pediatrics-Infectious Disease
Baylor College of Medicine
Houston, TX US
- Member
-
Dan L Duncan Comprehensive Cancer Center
Baylor College of Medicine
Houston, Texas United States
- Affiliate Member
-
Stem Cells and Regenerative Medicine Center
Center for Cell and Gene Therapy
Houston, Texas
- Co-Director
-
Medical Scientist Training Program
- Steering Committee
-
Pediatrician Scientist Training and Development Program
- Associate Vice-Chair for Research
-
Pediatrics
Baylor College of Medicine
HOUSTON
Addresses
- Pediatric Infectious Diseases (Office)
-
Texas Children's Feigin Center
Room: TXFC-1150
Houston, TX 77030
United States
Phone: (832) 824-4330
- Pediatric Infectious Diseases (Clinic)
-
Texas Children's Clinical Care Center
6701 Fannin St., 16th Floor
Houston, TX 77030
United States
Phone: (832) 824-4330
- King Lab (Lab)
-
Texas Children's Feigin Center
Suite C0.470.02
Houston, TX 77030
United States
Phone: (832) 824-4222
Education
- AB from Harvard University
- 06/1996 - Cambridge, Massachusetts United States
- Biochemical Sciences
- MD from Washington University School Of Medicine
- 05/2003 - St. Louis, Missouri United States
- PhD from Washington University School Of Medicine
- 05/2003 - St. Louis, Missouri United States
- Internship at Baylor College Of Medicine Affiliate Hospitals
- 06/2004 - Houston, Texas United States
- Pediatrics
- Residency at Baylor College Of Medicine Affiliate Hospitals
- 06/2007 - Houston, Texas United States
- Pediatrics
- Fellowship at Baylor College Of Medicine Affiliate Hospitals
- 06/2010 - Houston, Texas United States
- Pediatric Infectious Diseases
Certifications
- Board Certified in Pediatrics
- (11/14/2007 - 12/01/2017)
- American Board of Pediatrics
- Board Certified in Pediatric Infectious Diseases
- American Board of Pediatrics
- Fellow
- American Academy of Pediatrics
Professional Interests
- Role of interferon-gamma in hematopoietic stem cell regulation
Websites
Videos
Selected Publications
- Josefsdottir KS, Baldridge MT, Kadmon CS, King KY. "Antibiotics impair murine hematopoiesis by depleting the intestinal microbiota.." Blood. 2017 Feb 9;129(6):729-739. Pubmed PMID: 27879260
- Matatall KA, Jeong M, Chen S, Sun D, Chen F, Mo Q, Kimmel M, King KY. "Chronic Infection Depletes Hematopoietic Stem Cells through Stress-Induced Terminal Differentiation.." Cell Reports. 2016 Dec 6;7(10):2584-2595. Pubmed PMID: 27926863
- King KY, Goodell MA "Inflammatory modulation of HSCs: viewing the HSC as a foundation for the immune response.." Nat. Rev. Immunol.. 2011;11(10):685-92. Pubmed PMID: 21904387
- Kadmon CS, Landers CS, Li HS, Watowich SS, Rodriguez A, and King KY "MicroRNA-22 controls interferon alpha production and erythroid maturation in response to infectious stress." J Exp. Hematol. 2017;56:7-15. Pubmed PMID: 28911907
- King KY, Lew JD, Ha NP, Lin JS, Ma X, Graviss EA, Goodell MA "Polymorphic Allele of Human IRGM1 Is Associated with Susceptibility to Tuberculosis in African Americans.." PLoS ONE. 2011;6(1):e16317. Pubmed PMID: 21283700
- Baldridge MT, King KY, Boles NC, Weksberg DC, Goodell MA "Quiescent haematopoietic stem cells are activated by IFN-gamma in response to chronic infection.." Nature. 2010 Jun 10;465(7299):793-7. Pubmed PMID: 20535209
- Matatall KA, Shen CC, Challen GA, King KY "Type II Interferon Promotes Differentiation of Myeloid-Biased Hematopoietic Stem Cells." Stem Cells. 2014 Oct;
- Hannah Yan, Megan T. Baldridge, and Katherine Y. King "Hematopoiesis and the Bacterial Microbiome." Blood. 2018 Aug;132(6):559-564. Pubmed PMID: 29853538
- Daniel E. Morales-Mantilla and Katherine Y. King "The Role of Interferon-Gamma in Hematopoietic Stem Cell Development, Homeostasis, and Disease." Current Stem Cell Reports. 2018;4:264-271. Pubmed PMID: 30148048
- Brenot A, King KY, Janowiak B, Griffith O, Caparon MG "Contribution of glutathione peroxidase to the virulence of Streptococcus pyogenes.." Infect. Immun.. 2004 Jan;72(1):408-13. Pubmed PMID: 14688122
- King KY, Goodell MA "Direct conversion of skin cells into blood: alchemy or science?." Mol. Ther.. 2011 Feb;19(2):227-8. Pubmed PMID: 21289635
- King KY, Edwards MS, Word BM "Hepatitis associated with micafungin use in a preterm infant.." J Perinatol. 2009 Apr;29(4):320-2. Pubmed PMID: 19325554
- Rossi L, Lin KK, Boles NC, Yang L, King KY, Jeong M, Mayle A, Goodell MA "Less Is More: Unveiling the Functional Core of Hematopoietic Stem Cells through Knockout Mice.." Cell Stem Cell. 2012 Sep 7;11(3):302-17. Pubmed PMID: 22958929
- King K, Browning JC, Metry DW, Prestigiacomo J, Scollard D, Schutze GE, Stryjewska B, Schwarzwald H "Leprosy and international adoption: a case report and review of diagnostic and treatment dilemmas.." Pediatr. Infect. Dis. J.. 2009 Apr;28(4):322-5. Pubmed PMID: 19238115
- Brenot A, King KY, Caparon MG "The PerR regulon in peroxide resistance and virulence of Streptococcus pyogenes.." Mol. Microbiol.. 2005 Jan;55(1):221-34. Pubmed PMID: 15612930
- 42. Yan H, Walker FC, Ali A, Han H, Tan L, Veillon L, Lorenzi PL, Baldridge MT, and King KY "The bacterial microbiota regulates normal hematopoiesis via metabolite-induced type 1 interferon signaling." Blood Advances. 2022;6(6):1754-65. Pubmed PMID: 35143611
- Matatall KA, Kadmon CS, King KY "Detecting hematopoietic stem cell proliferation using BrdU incorporation." Methods Mol. Biol. 2018;1686:91-103. Pubmed PMID: 29030815
Projects
- Hematopoietic Stem Cell Responses to Infection
- My laboratory investigates the effects of infection and inflammation on hematopoietic stem cell biology. These findings will have implications for prevention and treatment of blood disorders related to inflammatory conditions, stem cell transplant outcomes, and immunity.
Funding
- Contribution of Infection to Preleukemic Clonal Hematopoiesis - #R01HL136333
- $1,289,623.00 ( 04/01/2017 - 03/31/2022 ) Grant funding from NIH (NHLBI)
- Inflammatory Regulation of Hematopoietic Stem and Progenitor Cells to Enhance Innate Immunity - #HL134880-A1
- $1,267,932.00 ( 08/02/2017 - 06/30/2021 ) Grant funding from NIH (NHLBI)
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