Email

kyk@bcm.edu

Positions

Associate Professor

Pediatrics-Infectious Disease
Baylor College of Medicine
Houston, TX US

Member

Dan L Duncan Comprehensive Cancer Center
Baylor College of Medicine
Houston, Texas United States

Affiliate Member

Stem Cells and Regenerative Medicine Center
Center for Cell and Gene Therapy
Houston, Texas

Co-Director

Medical Scientist Training Program

Steering Committee

Pediatrician Scientist Training and Development Program

Associate Vice-Chair for Research

Pediatrics
Baylor College of Medicine
HOUSTON

Addresses

Pediatric Infectious Diseases (Clinic)

Texas Children's Clinical Care Center
6701 Fannin St., 16th Floor
Houston, TX 77030
United States
Phone: (832) 824-4330

Pediatric Infectious Diseases (Office)

Texas Children's Feigin Center
Room: TXFC-1150
Houston, TX 77030
United States
Phone: (832) 824-4330

King Lab (Lab)

Texas Children's Feigin Center
Suite C0.470.02
Houston, TX 77030
United States
Phone: (832) 824-4222

Education

AB from Harvard University

06/1996 - Cambridge, Massachusetts United States

Biochemical Sciences

MD from Washington University School Of Medicine

05/2003 - St. Louis, Missouri United States

PhD from Washington University School Of Medicine

05/2003 - St. Louis, Missouri United States

Internship at Baylor College Of Medicine Affiliate Hospitals

06/2004 - Houston, Texas United States

Pediatrics

Residency at Baylor College Of Medicine Affiliate Hospitals

06/2007 - Houston, Texas United States

Pediatrics

Fellowship at Baylor College Of Medicine Affiliate Hospitals

06/2010 - Houston, Texas United States

Pediatric Infectious Diseases

Certifications

Board Certified in Pediatrics

(11/14/2007 - 12/01/2017)

American Board of Pediatrics

Board Certified in Pediatric Infectious Diseases

American Board of Pediatrics

Fellow

American Academy of Pediatrics

Professional Interests

• Role of interferon-gamma in hematopoietic stem cell regulation

Websites

Videos

Selected Publications

• Josefsdottir KS, Baldridge MT, Kadmon CS, King KY. "Antibiotics impair murine hematopoiesis by depleting the intestinal microbiota.." Blood.2017/February9;129(6):729-739. Pubmed PMID: 27879260
• Matatall KA, Jeong M, Chen S, Sun D, Chen F, Mo Q, Kimmel M, King KY. "Chronic Infection Depletes Hematopoietic Stem Cells through Stress-Induced Terminal Differentiation.." Cell Reports.2016/December6;7(10):2584-2595. Pubmed PMID: 27926863
• King KY, Goodell MA "Inflammatory modulation of HSCs: viewing the HSC as a foundation for the immune response.." Nat. Rev. Immunol..2011;11(10):685-92. Pubmed PMID: 21904387
• Kadmon CS, Landers CS, Li HS, Watowich SS, Rodriguez A, and King KY "MicroRNA-22 controls interferon alpha production and erythroid maturation in response to infectious stress." J Exp. Hematol.2017;56:7-15. Pubmed PMID: 28911907

Projects

Hematopoietic Stem Cell Responses to Infection

My laboratory investigates the effects of infection and inflammation on hematopoietic stem cell biology. These findings will have implications for prevention and treatment of blood disorders related to inflammatory conditions, stem cell transplant outcomes, and immunity.

Funding

Contribution of Infection to Preleukemic Clonal Hematopoiesis - #R01HL136333

$1,289,623.00 (04/01/2017 - 03/31/2022)

Grant funding from NIH (NHLBI)

Inflammatory Regulation of Hematopoietic Stem and Progenitor Cells to Enhance Innate Immunity - #HL134880-A1

$1,267,932.00 (08/02/2017 - 06/30/2021)

Grant funding from NIH (NHLBI)