Guilherme Vianna Silva, M.D., F.A.C.C.
Picture
Guilherme Vianna Silva, M.D., F.A.C.C.
Assistant Professor
Phone
Phone
Positions
- Assistant Professor
-
Medicine-Cardiology
Baylor College of Medicine
Houston, Texas United States
- Director of Structural Heart Disease
-
Baylor College of Medicine
Houston, Texas United States
Addresses
- Baylor Clinic (Clinic)
-
7200 Cambridge St
Suite 6C
Houston, TX 77030
United States
Phone: (713) 798-2545
- Baylor CHI St. Luke's Hospital (Clinic)
-
1101 Bates Ave
THI Clinic - Suite P115
Houston, TX 77030
United States
Phone: (713) 798-2776
Education
- MD from Federal University of Rio de Janeiro
- 12/1994 - Rio De Janeiro, Brazil
- Fellowship at Massachusetts General Hospital/Harvard Medical School
- 07/2013 - Boston, Massachusetts United States
- Structural Heart Disease
- Fellowship at Texas Heart Institute/St. Luke's Episcopal Hospital/Baylor College of Medicine
- 06/2008 - Houston, Texas United States
- Interventional Cardiology
- Fellowship at Texas Heart Institute/St. Luke's Episcopal Hospital/Baylor College of Medicine
- 06/2007 - Houston, Texas United States
- Adult Cardiology
- Residency at University of Texas Health Science Center
- 06/2003 - Houston, Texas United States
- Internal Medicine
Certifications
- Nuclear Cardiology
- Certification Board of Nuclear Cardiology
- Echocardiography
- National Board of Echocardiography
- Interventional Cardiology
- (11/01/2020 - 12/31/2030)
- American Board of Internal Medicine
- Cardiovascular Disease
- (10/31/2017 - 12/31/2027)
- American Board of Internal Medicine
- Internal Medicine
- (08/01/2003 - 12/31/2023)
- American Board of Internal Medicine
Honors & Awards
- The Tauber Award: Outstanding Cardiology Fellow
- Texas Heart Institute (07/2004 - 06/2007)
- Chief Interventional Cardiology Fellow
- Texas Heart Institute/Baylor College of Medicine
- Chief Cardiology Fellow
- Texas Heart Institute/Baylor College of Medicine
- That's The Way!
- An award given by BCM in recognition of exceptional patient experience
- BCM (05/2015)
- Top Doctors 2021
- Houstonia (09/2021)
Professional Interests
- Structural Heart Disease Intervention
- Interventional cardiology
- Cardiology
- Cardiovascular disease
Professional Statement
Guilherme Vianna Silva, M.D, is Director of Structural Heart Disease at Baylor College of Medicine and at the Texas Heart Institute, and Assistant Professor at Baylor College of Medicine.Dr. Silva is board certified in Cardiovascular Disease, Interventional Cardiology, Internal Medicine, Nuclear Cardiology and Echocardiography.
Dr. Silva earned his medical degree from the Federal University of Rio de Janeiro in Brazil in December of 1994. Upon completing his medical degree, he did three years of Cardiology training in Brazil. After coming to the United States, he completed three years of postgraduate training in Internal Medicine at The University of Texas-Houston. At the Texas Heart Institute in Houston, Silva completed four years (June 2003 – June 2007) of fellowship in Research and Adult Cardiology. During his training at the Texas Heart Institute, Dr. Silva held the position of Chief Cardiology Fellow and was given The Tauber Award for the Outstanding Cardiology Fellow of the 2007 graduating class. From July of 2007 to June of 2008, Dr. Silva completed his Interventional Cardiology Fellowship at the Texas Heart Institute and again held the position of Chief Interventional Cardiology Fellow. Finally, Dr. Silva completed a fellowship at the Massachusetts General Hospital/Harvard Medical School in Structural Heart Disease from July 2012 to July 2013.
The major focus of Dr. Silva has been in cardiovascular disease research and is one of the pioneers in the utilization of stem cells for treating heart attacks and heart failure. With over 40 full papers published in the peer-reviewed literature, over 100 abstracts, and 13 books and book chapters along with multiple invitations to teach in the United States and South America are a testimony of his commitment to clinical research and patient care. Dr. Silva’s academic work includes topics such as: stem cell therapy for heart disease, interventional cardiology, coronary imaging, and structural heart disease interventions.
Dr. Silva is an expert in complex interventional cardiology procedures, including; cardiac catheterization, percutaneous transluminal coronary angioplasty (PTCA), coronary stenting, peripheral vascular angioplasty and stenting, and rotational atherectomy. He has also specially trained in structural heart disease interventions and performs procedures such as Transcatheter Aortic Valve Replacement (TAVR), Percutaneous Patent Foramen Ovale (PFO) closure and Percutaneous Atrial septal Defect (ASD) closure and Percutaneous closure of Paraprosthetic Valvular Leaks repairs. Lastly, Dr. Silva also specializes on percutaneous techniques to treat Mitral Valve Disease. He also specializes in MitraClip, a less-invasive treatment option for certain people with mitral regurgitation who are high risk for surgery. Dr Silva and his Team have started to perform Transcatheter Mitral Valve Replacement (TMVR) and Pascal Tricuspid Transcatheter Edge-to-Edge Repair (TEER).
Websites
Selected Publications
- Gahremanpour A, Vela D, Zheng Y, Silva GV, Fodor W, Cardoso CO, Baimbridge F, Fernandes MR, Buja LM, Perin EC "Xenotransplantation of human unrestricted somatic stem cells in a pig model of acute myocardial infarction.." Xenotransplantation. 2013 Mar;20(2):110-22. Pubmed PMID: 23489741
- Dohmann HF, Perin EC, Borojevic R, Silva SA, Souza AL, Silva GV, Assad JA, Rossi MI, Mesquita CT, Dohmann HJ "[Sustained improvement in symptoms and exercise capacity up to six months after autologous transendocardial transplantation of bone marrow mononuclear cells in patients with severe ischemic heart disease]." Arq. Bras. Cardiol.. 2005 May;84(5):360-6. Pubmed PMID: 15917966
- Silva GV, Fernandes MR, Cardoso CO, Sanz RR, Oliveira EM, Jimenez-Quevedo P, Lopez J, Angeli FS, Zheng Y, Willerson JT, Perin EC "A dosing study of bone marrow mononuclear cells for transendocardial injection in a pig model of chronic ischemic heart disease.." Tex Heart Inst J. 2011;38(3):219-24. Pubmed PMID: 21720456
- Perin EC, Silva GV, Henry TD, Cabreira-Hansen MG, Moore WH, Coulter SA, Herlihy JP, Fernandes MR, Cheong BY, Flamm SD, Traverse JH, Zheng Y, Smith D, Shaw S, Westbrook L, Olson R, Patel D, Gahremanpour A, Canales J, Vaughn WK, Willerson JT "A randomized study of transendocardial injection of autologous bone marrow mononuclear cells and cell function analysis in ischemic heart failure (FOCUS-HF).." Am. Heart J.. 2011 Jun;161(6):1078-1087.e3. Pubmed PMID: 21641354
- Silva GV "Appropriateness criteria for coronary revascularization in stable-angina patients.." Tex Heart Inst J. 2012;39(2):235-6. Pubmed PMID: 22740740
- Fernandes MR, Silva GV, Caixeta A, Rati M, de Sousa e Silva NA, Perin EC "Assessing intermediate coronary lesions: angiographic prediction of lesion severity on intravascular ultrasound.." J Invasive Cardiol. 2007 Oct;19(10):412-6. Pubmed PMID: 17906342
- Perin EC, Silva GV, Sarmento-Leite R, Sousa AL, Howell M, Muthupillai R, Lambert B, Vaughn WK, Flamm SD "Assessing myocardial viability and infarct transmurality with left ventricular electromechanical mapping in patients with stable coronary artery disease: validation by delayed-enhancement magnetic resonance imaging.." Circulation. 2002 Aug 20;106(8):957-61. Pubmed PMID: 12186800
- Perin EC, Silva GV "Autologous cell-based therapy for ischemic heart disease: clinical evidence, proposed mechanisms of action, and current limitations.." Catheter Cardiovasc Interv. 2009 Feb 15;73(3):281-8. Pubmed PMID: 19213080
- Silva GV, Perin EC, Dohmann HF, Borojevic R, Silva SA, Sousa AL, Assad JA, Vaughn WK, Mesquita CT, Belém L, Carvalho AC, Dohmann HJ, Barroso do Amaral E, Coutinho J, Branco R, Oliveira E, Willerson JT "Catheter-based transendocardial delivery of autologous bone-marrow-derived mononuclear cells in patients listed for heart transplantation.." Tex Heart Inst J. 2004;31(3):214-9. Pubmed PMID: 15562839
- Perin EC, Silva GV "Cell-based therapy for chronic ischemic heart disease--a clinical perspective.." Cardiovasc Ther. 2011 Jun;29(3):211-7. Pubmed PMID: 20955540
- Silva GV, Fernandes MR, Madonna R, Clubb F, Oliveira E, Jimenez-Quevedo P, Branco R, Lopez J, Angeli FS, Sanz-Ruiz R, Vaughn WK, Zheng Y, Baimbridge F, Canales J, Cardoso CO, Assad JA, Falotico R, Perin EC "Comparative healing response after sirolimus- and paclitaxel-eluting stent implantation in a pig model of restenosis.." Catheter Cardiovasc Interv. 2009 May 1;73(6):801-8. Pubmed PMID: 19309735
- Perin EC, Silva GV, Assad JA, Vela D, Buja LM, Sousa AL, Litovsky S, Lin J, Vaughn WK, Coulter S, Fernandes MR, Willerson JT "Comparison of intracoronary and transendocardial delivery of allogeneic mesenchymal cells in a canine model of acute myocardial infarction.." J. Mol. Cell. Cardiol.. 2008 Mar;44(3):486-95. Pubmed PMID: 18061611
- Sarmento-Leite R, Silva GV, Dohman HF, Rocha RM, Dohman HJ, de Mattos ND, Carvalho LA, Gottechall CA, Perin EC "Comparison of left ventricular electromechanical mapping and left ventricular angiography: defining practical standards for analysis of NOGA maps.." Tex Heart Inst J. 2003;30(1):19-26. Pubmed PMID: 12638666
- Fernandes MR, Silva GV, Perin EC "Contralateral angiography in acute myocardial infarction patients: is less really more?." Tex Heart Inst J. 2012;39(3):365-6. Pubmed PMID: 22719145
- Silva GV, Fernandes MR, Cardoso CO, Miranda WR, Strickman N, Mortazavi A, Hernandez-Vila EA, Achari A, Krajcer Z "Cryoplasty for peripheral artery disease in an unselected patient population in a tertiary center.." Tex Heart Inst J. 2011;38(2):122-6. Pubmed PMID: 21494517
- Traverse JH, Henry TD, Ellis SG, Pepine CJ, Willerson JT, Zhao DX, Forder JR, Byrne BJ, Hatzopoulos AK, Penn MS, Perin EC, Baran KW, Chambers J, Lambert C, Raveendran G, Simon DI, Vaughan DE, Simpson LM, Gee AP, Taylor DA, Cogle CR, Thomas JD, Silva GV, J "Effect of intracoronary delivery of autologous bone marrow mononuclear cells 2 to 3 weeks following acute myocardial infarction on left ventricular function: the LateTIME randomized trial.." JAMA. 2011 Nov 16;306(19):2110-9. Pubmed PMID: 22084195
- Perin EC, Willerson JT, Pepine CJ, Henry TD, Ellis SG, Zhao DX, Silva GV, Lai D, Thomas JD, Kronenberg MW, Martin AD, Anderson RD, Traverse JH, Penn MS, Anwaruddin S, Hatzopoulos AK, Gee AP, Taylor DA, Cogle CR, Smith D, Westbrook L, Chen J, Handberg E, O "Effect of transendocardial delivery of autologous bone marrow mononuclear cells on functional capacity, left ventricular function, and perfusion in chronic heart failure: the FOCUS-CCTRN trial.." JAMA. 2012 Apr 25;307(16):1717-26. Pubmed PMID: 22447880
- Perin EC, Silva GV, Fernandes MR, Munger T, Pandey A, Sehra R, Talcott M, Bichard CJ, Creed J, Wong JW, Oliveira EM, Zheng Y, Canales J, Cardoso CO, Patterson MS, Serruys PW "First experience with remote left ventricular mapping and transendocardial cell injection with a novel integrated magnetic navigation-guided electromechanical mapping system.." 2007 May;3(1):142-8. Pubmed PMID: 19737699
- Vela DC, Silva GV, Assad JA, Sousa AL, Coulter S, Fernandes MR, Perin EC, Willerson JT, Buja LM "Histopathological study of healing after allogenic mesenchymal stem cell delivery in myocardial infarction in dogs.." J. Histochem. Cytochem.. 2009 Feb;57(2):167-76. Pubmed PMID: 19001635
- Zheng Y, Fernandes MR, Silva GV, Cardoso CO, Canales J, Gahramenpour A, Baimbridge F, da Graça Cabreira-Hansen M, Perin EC "Histopathological validation of electromechanical mapping in assessing myocardial viability in a porcine model of chronic ischemia.." Exp Clin Cardiol. 2008;13(4):198-203. Pubmed PMID: 19343167
- Perin EC, Silva GV, Vela DC, Zheng Y, Baimbridge F, Gahremanpour A, Quan X, Hahn W, Kim J, Wood K, Kitamura M "Human hepatocyte growth factor (VM202) gene therapy via transendocardial injection in a pig model of chronic myocardial ischemia.." J. Card. Fail.. 2011 Jul;17(7):601-11. Pubmed PMID: 21703533
- de Quadros AS, Sarmento-Leite R, Gottschall CA, Silva GV, Perin EC "Hyperexpansion of coronary stents and clinical outcomes.." Tex Heart Inst J. 2006;33(4):437-44. Pubmed PMID: 17215966
- Perin EC, Tian M, Marini FC, Silva GV, Zheng Y, Baimbridge F, Quan X, Fernandes MR, Gahremanpour A, Young D, Paolillo V, Mukhopadhyay U, Borne AT, Uthamanthil R, Brammer D, Jackson J, Decker WK, Najjar AM, Thomas MW, Volgin A, Rabinovich B, Soghomonyan S, "Imaging long-term fate of intramyocardially implanted mesenchymal stem cells in a porcine myocardial infarction model.." PLoS ONE. 2011;6(9):e22949. Pubmed PMID: 21912635
- Perin EC, Dohmann HF, Borojevic R, Silva SA, Sousa AL, Silva GV, Mesquita CT, Belém L, Vaughn WK, Rangel FO, Assad JA, Carvalho AC, Branco RV, Rossi MI, Dohmann HJ, Willerson JT "Improved exercise capacity and ischemia 6 and 12 months after transendocardial injection of autologous bone marrow mononuclear cells for ischemic cardiomyopathy.." Circulation. 2004 Sep 14;110(11):II213-8. Pubmed PMID: 15364865
- Rocha RM, Silva GV, de Albuquerque DC, Tura BR, Albanesi Filho FM "Influence of spironolactone therapy on thiamine blood levels in patients with heart failure.." Arq. Bras. Cardiol.. 2008 May;90(5):324-8. Pubmed PMID: 18516403
- Perin EC, Silva GV, Sarmento-Leite R "Left ventricular electromechanical mapping: a case study of functional assessment in coronary intervention.." Tex Heart Inst J. 2000;27(3):253-6. Pubmed PMID: 11093409
- Perin EC, Silva GV, Sarmento-Leite R, Vaughn WK, Fish RD, Ferguson JJ "Left ventricular electromechanical mapping: preliminary evidence of electromechanical changes after successful coronary intervention.." Am. Heart J.. 2002 Oct;144(4):693-701. Pubmed PMID: 12360167
- Perin EC, Silva GV, Zheng Y, Gahremanpour A, Canales J, Patel D, Fernandes MR, Keller LH, Quan X, Coulter SA, Moore WH, Herlihy JP, Willerson JT "Randomized, double-blind pilot study of transendocardial injection of autologous aldehyde dehydrogenase-bright stem cells in patients with ischemic heart failure.." Am. Heart J.. 2012 Mar;163(3):415-421.e1. Pubmed PMID: 22424012
- Fernandes MR, Fish RD, Canales J, Aliota J, Silva GV, Perin EC, Elayda MA, Wilson JM "Restoration of microcirculatory patency after myocardial infarction: results of current coronary interventional strategies and techniques.." Tex Heart Inst J. 2012;39(3):342-50. Pubmed PMID: 22719142
- Perin EC, Silva GV "Stem cell therapy for cardiac diseases.." Curr. Opin. Hematol.. 2004 Nov;11(6):399-403. Pubmed PMID: 15548994
- Perin EC, Silva GV, Willerson JT "Training on the use of transendocardial delivery of biologics for cardiac regeneration.." JACC Cardiovasc Interv. 2010 Sep;3(9):991. Pubmed PMID: 20850103
- Perin EC, Dohmann HF, Borojevic R, Silva SA, Sousa AL, Mesquita CT, Rossi MI, Carvalho AC, Dutra HS, Dohmann HJ, Silva GV, Belém L, Vivacqua R, Rangel FO, Esporcatte R, Geng YJ, Vaughn WK, Assad JA, Mesquita ET, Willerson JT "Transendocardial, autologous bone marrow cell transplantation for severe, chronic ischemic heart failure.." Circulation. 2003 May 13;107(18):2294-302. Pubmed PMID: 12707230
- Fernandes MR, Silva GV, Zheng Y, Oliveira EM, Cardoso CO, Canales J, Sanz-Ruiz R, Jimenez-Quevedo P, Baimbridge F, Perin EC "Validation of QwikStar Catheter for left ventricular electromechanical mapping with NOGA XP system.." Tex Heart Inst J. 2008;35(3):240-4. Pubmed PMID: 18941605
Memberships
- Brazilian Cardiology Society
- Member
- Harris County Medical Society
- Member
- Massachusetts Medical Society
- Member
Languages
Portuguese, Spanish
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