Positions
- Professor
-
Pediatrics
Children's Nutrition Research Center
Baylor College of Medicine
Houston, TX US
- Professor
-
Pediatrics
Pediatric Endocrinology and Diabetes
Texas Children's Hospital
Houston, Texas United States
Addresses
- TCH-Clinical Care Center (Clinic)
-
6701 Fannin St.
Houston, TX 77030
United States
Phone: (832) 822-3760
- Childrens Nutrition Research Ct (Office)
-
Room: CNRC-7072
Houston, TX 77030
United States
Education
- Fellowship at Children's Hospital Of Pittsburgh
- 06/2003 - Pittsburgh, Pennsylvania United States
- Residency at State University Of New York Upstate Medical University
- 06/2000 - Syracuse, New York United States
- MD from American University Of Beirut School Of Medicine
- 06/1995 - Beirut, Lebanon
- B.S. from American University Of Beirut
- 01/1991 - Beirut, Lebanon
Certifications
- Pediatric Endocrinology
- American Board of Pediatrics
Websites
Selected Publications
- Ishita Jindal; Maurice Puyau; Anne Adolph; Nancy Butte; Salma Musaad; Fida Bacha "The relationship of sleep duration and quality to energy expenditure and physical activity in children." Pediatr Obes. 2021 Jun 16;16(6):e12751. Pubmed PMID: 33191656
- Fida Bacha; Sara Klinepeter Bartz; Maurice Puyau; Anee Adolph; Susan Sharma "Metabolic flexibility across the spectrum of glycemic regulation in youth." JCI Insight. 2021 Feb 22;6(4):e146000. Pubmed PMID: 33616083
- Redondo MJ, Bacha F "GLP-1 Receptor Agonist as Adjuvant Therapy in Type 1 Diabetes: No Apparent Benefit for Beta-Cell Function or Glycemia." J Clin Endocrinol Metab. 2020 Aug 1;105(8):e3000-e3002. Pubmed PMID: 32485735
- Bacha F "FDA approval of GLP-1 receptor agonist (liraglutide) for use in children." Lancet Child Adolesc Health. 2019 Jul 22;3(9):595-597. Pubmed PMID: 31345736
- Lee S, Bacha F, Hannon T, Kuk JL, Boesch C, Arslanian S "Effects of aerobic versus resistance exercise without caloric restriction on abdominal fat, intrahepatic lipid, and insulin sensitivity in obese adolescent boys: a randomized, controlled trial.." Diabetes. 2012 Nov;61(11):2787-95. Pubmed PMID: 22751691
- Bacha F, Pyle L, Nadeau K, Cuttler L, Goland R, Haymond M, Levitsky L, Lynch J, Weinstock RS, White NH, Caprio S, Arslanian S "Determinants of glycemic control in youth with type 2 diabetes at randomization in the TODAY study.." Pediatr Diabetes. 2012 Aug;13(5):376-83. Pubmed PMID: 22332798
- De Las Heras J, Lee S, Bacha F, Tfayli H, Arslanian S "Cross-Sectional Association between Blood Pressure, in vivo Insulin Sensitivity and Adiponectin in Overweight Adolescents.." Horm Res Paediatr. 2011;76(6):379-85. Pubmed PMID: 21968570
- Burns SF, Bacha F, Lee SJ, Tfayli H, Gungor N, Arslanian SA "Declining {beta}-Cell Function Relative to Insulin Sensitivity With Escalating OGTT 2-h Glucose Concentrations in the Nondiabetic Through the Diabetic Range in Overweight Youth.." Diabetes Care. 2011 Sep;34(9):2033-40. Pubmed PMID: 21750275
- Bacha F, Lee S, Gungor N, Arslanian SA "From Pre-Diabetes to Type 2 Diabetes in Obese Youth: Pathophysiological characteristics along the spectrum of glucose dysregulation.." Diabetes Care. 2010 Oct;33(10):2225-31. Pubmed PMID: 20592052
- Lee S, Bacha F, Gungor N, Arslanian S "Comparison of different definitions of pediatric metabolic syndrome: relation to abdominal adiposity, insulin resistance, adiponectin, and inflammatory biomarkers.." J. Pediatr.. 2008 Feb;152(2):177-84. Pubmed PMID: 18206686
- Lee S, Bacha F, Gungor N, Arslanian SA "Cardiorespiratory fitness in youth: relationship to insulin sensitivity and beta-cell function.." Obesity (Silver Spring). 2006 Sep;14(9):1579-85. Pubmed PMID: 17030969
- Bacha F, Saad R, Gungor N, Arslanian SA "Are obesity-related metabolic risk factors modulated by the degree of insulin resistance in adolescents?." Diabetes Care. 2006 Jul;29(7):1599-604. Pubmed PMID: 16801585
- Bacha F, Saad R, Gungor N, Arslanian SA "Does adiponectin explain the lower insulin sensitivity and hyperinsulinemia of African-American children?." Pediatr Diabetes. 2005 Jun;6(2):100-2. Pubmed PMID: 15963038
- Arslanian SA, Bacha F, Saad R, Gungor N "Family history of type 2 diabetes is associated with decreased insulin sensitivity and an impaired balance between insulin sensitivity and insulin secretion in white youth.." Diabetes Care. 2005 Jan;28(1):115-9. Pubmed PMID: 15616243
- Bacha F, Saad R, Gungor N, Arslanian SA "Adiponectin in youth: relationship to visceral adiposity, insulin sensitivity, and beta-cell function.." Diabetes Care. 2004 Feb;27(2):547-52. Pubmed PMID: 14747242
- Bacha F, Arslanian SA "Ghrelin and peptide YY in youth: are there race-related differences?." J. Clin. Endocrinol. Metab.. 2006 Aug;91(8):3117-22. Pubmed PMID: 16720664
- Bacha F, Arslanian SA "Ghrelin suppression in overweight children: a manifestation of insulin resistance?." J. Clin. Endocrinol. Metab.. 2005 May;90(5):2725-30. Pubmed PMID: 15728212
- Sjaarda LA, Michaliszyn SF, Lee S, Tfayli H, Bacha F, Farchoukh L, Arslanian SA "HbA1c Diagnostic Categories and ß-Cell Function Relative to Insulin Sensitivity in Overweight/Obese Adolescents.." Diabetes Care. 2012 Dec;35(12):2559-63. Pubmed PMID: 22912428
- Hannon TS, Bacha F, Lin Y, Arslanian SA "Hyperinsulinemia in African-American adolescents compared with their American white peers despite similar insulin sensitivity: a reflection of upregulated beta-cell function?." Diabetes Care. 2008 Jul;31(7):1445-7. Pubmed PMID: 18417751
- Bacha F, Gungor N, Lee S, Arslanian SA "In vivo insulin sensitivity and secretion in obese youth: what are the differences between normal glucose tolerance, impaired glucose tolerance, and type 2 diabetes?." Diabetes Care. 2009 Jan;32(1):100-5. Pubmed PMID: 18835946
- Bacha F, Gungor N, Lee S, de Las Heras J, Arslanian S "Indices of Insulin Secretion during a Liquid Mixed-Meal Test in Obese Youth with Diabetes.." J. Pediatr.. 2013 May;162(5):924-9. Pubmed PMID: 23290511
- Amis T, Di Somma E, Bacha F, Wheatley J "Influence of intra-oral maxillary sports mouthguards on the airflow dynamics of oral breathing.." Med Sci Sports Exerc. 2000 Feb;32(2):284-90. Pubmed PMID: 10694108
- Lee S, Gungor N, Bacha F, Arslanian S "Insulin resistance: link to the components of the metabolic syndrome and biomarkers of endothelial dysfunction in youth.." Diabetes Care. 2007 Aug;30(8):2091-7. Pubmed PMID: 17475936
- Tfayli H, Bacha F, Gungor N, Arslanian S "Islet Cell Antibody-Positive Versus -Negative Phenotypic Type 2 Diabetes in Youth: Does the oral glucose tolerance test distinguish between the two?." Diabetes Care. 2010 Mar;33(3):632-8. Pubmed PMID: 20028940
- Bacha F, Gungor N, Arslanian SA "Measures of beta-cell function during the oral glucose tolerance test, liquid mixed-meal test, and hyperglycemic clamp test.." J. Pediatr.. 2008 May;152(5):618-21. Pubmed PMID: 18410762
- Sjaarda L, Lee S, Tfayli H, Bacha F, Bertolet M, Arslanian S "Measuring ß-Cell Function Relative to Insulin Sensitivity in Youth: Does the hyperglycemic clamp suffice?." Diabetes Care. 2013 Jun;36(6):1607-12. Pubmed PMID: 23275361
- Michaliszyn SF, Sjaarda LA, Mihalik SJ, Lee S, Bacha F, Chace DH, De Jesus VR, Vockley J, Arslanian SA "Metabolomic Profiling of Amino Acids and ß-Cell Function Relative to Insulin Sensitivity in Youth.." J. Clin. Endocrinol. Metab.. 2012 Nov;97(11):E2119-24. Pubmed PMID: 22977272
- Mihalik SJ, Michaliszyn SF, de Las Heras J, Bacha F, Lee S, Chace DH, Dejesus VR, Vockley J, Arslanian SA "Metabolomic Profiling of Fatty Acid and Amino Acid Metabolism in Youth With Obesity and Type 2 Diabetes: Evidence for enhanced mitochondrial oxidation.." Diabetes Care. 2012 Mar;35(3):605-11. Pubmed PMID: 22266733
- Bacha F, Hoo JJ "New syndrome characterized by sparse hair, prominent nose, small mouth, micrognathia, cleft palate, crumpled upper helices, digit anomaly, and mild developmental delay.." Am. J. Med. Genet.. 2001 Jun 1;101(1):70-3. Pubmed PMID: 11343342
- Bacha F, Saad R, Gungor N, Janosky J, Arslanian SA "Obesity, regional fat distribution, and syndrome X in obese black versus white adolescents: race differential in diabetogenic and atherogenic risk factors.." J. Clin. Endocrinol. Metab.. 2003 Jun;88(6):2534-40. Pubmed PMID: 12788850
- Tfayli H, Jung Lee S, Bacha F, Arslanian S "One-hour plasma glucose concentration during the OGTT: what does it tell about ß-cell function relative to insulin sensitivity in overweight/obese children?." Pediatr Diabetes. 2011 Sep;12(6):572-9. Pubmed PMID: 21466647
- Sjaarda LG, Bacha F, Lee S, Tfayli H, Andreatta E, Arslanian S "Oral disposition index in obese youth from normal to prediabetes to diabetes: relationship to clamp disposition index.." J. Pediatr.. 2012 Jul;161(1):51-7. Pubmed PMID: 22325254
- Tfayli H, Bacha F, Gungor N, Arslanian S "Phenotypic type 2 diabetes in obese youth: insulin sensitivity and secretion in islet cell antibody-negative versus -positive patients.." Diabetes. 2009 Mar;58(3):738-44. Pubmed PMID: 19073767
- Bacha F, Gungor N, Lee S, Arslanian SA "Progressive deterioration of ß-cell function in obese youth with type 2 diabetes.." Pediatr Diabetes. 2013 Mar;14(2):106-11. Pubmed PMID: 22913617
- Lee S, Bacha F, Gungor N, Arslanian SA "Racial differences in adiponectin in youth: relationship to visceral fat and insulin sensitivity.." Diabetes Care. 2006 Jan;29(1):51-6. Pubmed PMID: 16373895
- Libman IM, Barinas-Mitchell E, Marcovina S, Bacha F, Hannon T, Tfayli H, Lee SJ, Bansal S, Robertson R, Arslanian S "ß-cell autoimmunity in overweight non-diabetic youth: any implications?." Pediatr Diabetes. 2011 May;12(3):207-11. Pubmed PMID: 21518410
- George L, Bacha F, Lee S, Tfayli H, Andreatta E, Arslanian S "Surrogate Estimates of Insulin Sensitivity in Obese Youth along the Spectrum of Glucose Tolerance from Normal to Prediabetes to Diabetes.." J. Clin. Endocrinol. Metab.. 2011 Jul;96(7):2136-45. Pubmed PMID: 21508130
- Bacha F, Gungor N, Lee S, Arslanian SA "Type 2 diabetes in youth: are there racial differences in ß-cell responsiveness relative to insulin sensitivity?." Pediatr Diabetes. 2012 May;13(3):259-65. Pubmed PMID: 21933317
- Gungor N, Hannon T, Libman I, Bacha F, Arslanian S "Type 2 diabetes mellitus in youth: the complete picture to date.." Pediatr. Clin. North Am.. 2005 Dec;52(6):1579-609. Pubmed PMID: 16301084
- Hannon TS, Bacha F, Lee SJ, Janosky J, Arslanian SA "Use of markers of dyslipidemia to identify overweight youth with insulin resistance.." Pediatr Diabetes. 2006 Oct;7(5):260-6. Pubmed PMID: 17054447
- Lee S, Bacha F, Gungor N, Arslanian SA "Waist circumference is an independent predictor of insulin resistance in black and white youths.." J. Pediatr.. 2006 Feb;148(2):188-94. Pubmed PMID: 16492427
- Lee S, Bacha F, Arslanian SA "Waist circumference, blood pressure, and lipid components of the metabolic syndrome.." J. Pediatr.. 2006 Dec;149(6):809-16. Pubmed PMID: 17137898
- Gungor N, Bacha F, Saad R, Janosky J, Arslanian S "Youth type 2 diabetes: insulin resistance, beta-cell failure, or both?." Diabetes Care. 2005 Mar;28(3):638-44. Pubmed PMID: 15735201
- Bacha F, Domachowske JB "Pasteurella multocida pneumonia in an adolescent with Duchenne's muscular dystrophy following exposure to his helper dog.." Clin Pediatr (Phila). 2001 Mar;40(3):159-61. Pubmed PMID: 11307962
- Shah AS, El Ghormli L, Vajravelu ME, Bacha F, Farrell RM, Gidding SS, Levitt Katz LE, Tryggestad JB, White NH, Urbina EM "Heart Rate Variability and Cardiac Autonomic Dysfunction: Prevalence, Risk Factors, and Relationship to Arterial Stiffness in the Treatment Options for Type 2 Diabetes in Adolescents and Youth (TODAY) Study." Diabetes Care. 2019 Nov;42(11):2143-2150. Pubmed PMID: 31501226
- Kim JY, Tfayli H, Bacha F, Lee S, Michaliszyn SF, Yousuf S, Gebara N, Arslanian S "β-cell function, incretin response, and insulin sensitivity of glucose and fat metabolism in obese youth: Relationship to OGTT-time-to-glucose-peak." Pediatr Diabetes. 2020 Nov 14;21(1):18-27. Pubmed PMID: 31677208
- Joon Young Kim; Hala Tfayli; Fida Bacha; SoJung Lee; Nour Gebara; Silva Arslanian "β-cell impairment and clinically meaningful alterations in glycemia in obese youth across the glucose tolerance spectrum." Metabolism. 2020 Aug 22;112 Pubmed PMID: 32835760
- hah VN, Bailey R, Wu M, Foster NC, Pop-Busui R, Katz M, Crandall J, Bacha F, Nadeau K, Libman I, Hiers P, Mizokami-Stout K, DiMeglio LA, Sherr J, Pratley R, Agarwal S, Snell-Bergeon J, Cengiz E, Polsky S, Mehta SN "Risk Factors for Cardiovascular Disease (CVD) in Adults with Type 1 Diabetes: Findings from Prospective Real-life T1D Exchange Registry." J Clin Endocrinol Metab .. 2020 May 1;105(5):e2032-2038. Pubmed PMID: 31955209
- Bacha F, El Ghormli L, Arslanian S, Zeitler P, Laffel LM, Levitt Katz LE, Gandica R, Chang NT, Sprague JE, Macleish SA "Predictors of response to insulin therapy in youth with poorly-controlled type 2 diabetes in the TODAY trial." Pediatr Diabetes. 2019 Nov;20(7):871-879. Pubmed PMID: 31418516
- Tryggestad JB, Shah RD, Braffett BH, Bacha F, Gidding SS, Gubitosi-Klug RA, Shah AS, Urbina EM, Levitt Katz LE "Circulating adhesion molecules and associations with HbA1c, hypertension, nephropathy, and retinopathy in the Treatment Options for type 2 Diabetes in Adolescent and Youth study." Pediatr Diabetes. 2020 Sep 1;21(6):923-931. Pubmed PMID: 32501612
- Kim JY, Bacha F, Tfayli H, Michaliszyn SF, Yousuf S, Arslanian S "Adipose Tissue Insulin Resistance in Youth on the Spectrum From Normal Weight to Obese and From Normal Glucose Tolerance to Impaired Glucose Tolerance to Type 2 Diabetes." Diabetes Care. 2019 Feb 1;42(2):265-272. Pubmed PMID: 30455334
- Bacha F, Bartz SK, Tomsa A, Sharma S "Free Vitamin D: Relationship to Insulin Sensitivity and Vascular Health in Youth." J Pediatr. 2019 Sep 1;212:28-34. Pubmed PMID: 31201030
- Arslanian S, Bacha F, Grey M, Marcus MD, White NH, Zeitler P "Evaluation and Management of Youth-Onset Type 2 Diabetes: A Position Statement by the American Diabetes Association." Diabetes Care. 2017 Dec 1;41(12):2648-2668. Pubmed PMID: 30425094
- Tamborlane WV, Chang P, Kollman C, Klingensmith GJ, Ruedy K, Gal RL, Van Name M, Bacha F, Willi S, Beck RW "Eligibility for clinical trials is limited for youth with type 2 diabetes: Insights from the Pediatric Diabetes Consortium T2D Clinic Registry." Pediatric Diabetes Consortium. 2018 Dec 1;19(8):1379-1384. Pubmed PMID: 30175440
- Arslanian S, El Ghormli L, Young Kim J, Bacha F, Chan C, Ismail HM, Levitt Katz LE, Levitsky L, Tryggestad JB, White NH; TODAY Study Group "The Shape of the Glucose Response Curve During an Oral Glucose Tolerance Test: Forerunner of Heightened Glycemic Failure Rates and Accelerated Decline in β-Cell Function in TODAY." Diabetes Care. 2019 Jan 1;42(1):164-172. Pubmed PMID: 30455329
Projects
- Determinants of Subclinical Coronary Atherosclerosis and Endothelial Dysfunction in Youth.
- USDA/ARS- Thrasher Research Fund
- Determinants of Endothelial Dysfunction in Obese Youth with and without Type 2 diabetes
- USDA/ARS
- This project evaluated the effects of obesity and type 2 diabetes on vascular health and its determinants in youth.
- Treatment Options for Type 2 Diabetes in Adolescents and Youth (TODAY)
- NIh-NIDDK
- T1D Exchange - A Randomized Trial of Metformin as Adjunct Therapy for Overweight
- Pediatric Diabetes Consortium for Type 2 Diabetes
- Ectopic Hepatic Fat in Hispanic Youth: Risk for Endothelial Dysfunction
- Preeclampsia and Fetal Origins of Childhood Insulin Resistance and Risk for Type 2 Diabetes and Cardiovascular Disease.
- Bone Health in Obese Youth with and without Type 2 diabetes
- USDA/ARS (10/2019 - 09/2024)
- Investigate the effect of adiposity, adipokine dysregulation (the balance of circulating anti-inflammatory vs. proinflammatory factors) and vitamin D concentrations on bone microarchitecture (cortical porosity, trabecular thickness), bone biomarkers and endothelial function in youth with and without abnormalities in glucose metabolism.
- Type 2 Diabetes and Bone Health in Youth
- NIH-NICHD
- Understanding and Targeting the Pathophysiology of Youth-onset Type 2 Diabetes
- NIH-NIDDK
Memberships
- Pediatric Endocrine Society
- American Diabetes Association
- The Endocrine Society
- Society for Pediatric Research
- (11/2006)
- Androgen Excess-PCOS Society
- American Heart Association
- American Academy of Clinical Endocrinologists
- The Obesity Society
- American Academy of Pediatrics
- Fellow (01/2014)
- American Pediatric Society
- (01/2018)
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