Fida Bacha, MD

Professor

(832) 822-3670

Email

fbacha@bcm.edu

Positions

Professor: Pediatrics
Children's Nutrition Research Center
Baylor College of Medicine
Houston, TX, US

Professor: Pediatrics
Pediatric Endocrinology and Diabetes
Texas Children's Hospital
Houston, Texas, United States

Addresses

TCH-Clinical Care Center (Clinic): 6701 Fannin St.
Houston, TX, 77030
United States
Phone: (832) 822-3760

Childrens Nutrition Research Ct (Office): Room: CNRC-7072
Houston, TX, 77030
United States

TCH-Clinical Care Center (Hospital): 6701 Fannin St.
Houston, TX, 77030
United States
Phone: (832) 822-3760

Education

Fellowship at Children's Hospital Of Pittsburgh: 06/2003 - Pittsburgh, Pennsylvania, United States

Residency at State University Of New York Upstate Medical University: 06/2000 - Syracuse, New York, United States

MD from American University Of Beirut School Of Medicine: 06/1995 - Beirut, Lebanon

B.S. from American University Of Beirut: 01/1991 - Beirut, Lebanon

Certifications

Pediatric Endocrinology: American Board of Pediatrics

Websites

VIICTR Publications List

Director-Energy Metabolism Unit

Director-Metabolic Research Unit

Selected Publications

Nadeau K, Arslanian S, Bacha F, Caprio S, Chao L, Farrell R, Hughan K, Rayas M, Tung M, El ghormli L. " Insulin clearance at randomization and in response to treatment in youth with type 2 diabetes from the Treatment Options for Diabetes in Adolescents and Youth (TODAY) Study " Diabetologia. 2025 Mar ; 68 (3) : 676-687.
Pubmed PMID: 39706874.
Puyau M, Shypailo R, Butte N, Musaad S, Bacha F. " Prediction models of basal energy expenditure in children and adolescents across the BMI spectrum based on room calorimetry: a cross-sectional cohort study " AJCN. 2025 Feb ; 121 (2) : 284-292.
Pubmed PMID: 39653177.
Ishita Jindal; Maurice Puyau; Anne Adolph; Nancy Butte; Salma Musaad; Fida Bacha. " The relationship of sleep duration and quality to energy expenditure and physical activity in children " Pediatr Obes. 2021 Jun 16; 16 (6) : e12751.
Pubmed PMID: 33191656.
Fida Bacha; Sara Klinepeter Bartz; Maurice Puyau; Anee Adolph; Susan Sharma. " Metabolic flexibility across the spectrum of glycemic regulation in youth " JCI Insight. 2021 Feb 22; 6 (4) : e146000.
Pubmed PMID: 33616083.
Kim JY, Tfayli H, Bacha F, Lee S, Michaliszyn SF, Yousuf S, Gebara N, Arslanian S. " β-cell function, incretin response, and insulin sensitivity of glucose and fat metabolism in obese youth: Relationship to OGTT-time-to-glucose-peak " Pediatr Diabetes. 2020 Nov 14; 21 (1) : 18-27.
Pubmed PMID: 31677208.
Tryggestad JB, Shah RD, Braffett BH, Bacha F, Gidding SS, Gubitosi-Klug RA, Shah AS, Urbina EM, Levitt Katz LE. " Circulating adhesion molecules and associations with HbA1c, hypertension, nephropathy, and retinopathy in the Treatment Options for type 2 Diabetes in Adolescent and Youth study " Pediatr Diabetes. 2020 Sep 1; 21 (6) : 923-931.
Pubmed PMID: 32501612.
Joon Young Kim; Hala Tfayli; Fida Bacha; SoJung Lee; Nour Gebara; Silva Arslanian. " β-cell impairment and clinically meaningful alterations in glycemia in obese youth across the glucose tolerance spectrum " Metabolism. 2020 Aug 22; 112
Pubmed PMID: 32835760.
Redondo MJ, Bacha F. " GLP-1 Receptor Agonist as Adjuvant Therapy in Type 1 Diabetes: No Apparent Benefit for Beta-Cell Function or Glycemia " J Clin Endocrinol Metab. 2020 Aug 1; 105 (8) : e3000-e3002.
Pubmed PMID: 32485735.
hah VN, Bailey R, Wu M, Foster NC, Pop-Busui R, Katz M, Crandall J, Bacha F, Nadeau K, Libman I, Hiers P, Mizokami-Stout K, DiMeglio LA, Sherr J, Pratley R, Agarwal S, Snell-Bergeon J, Cengiz E, Polsky S, Mehta SN. " Risk Factors for Cardiovascular Disease (CVD) in Adults with Type 1 Diabetes: Findings from Prospective Real-life T1D Exchange Registry " J Clin Endocrinol Metab .. 2020 May 1; 105 (5) : e2032-2038.
Pubmed PMID: 31955209.
Shah AS, El Ghormli L, Vajravelu ME, Bacha F, Farrell RM, Gidding SS, Levitt Katz LE, Tryggestad JB, White NH, Urbina EM. " Heart Rate Variability and Cardiac Autonomic Dysfunction: Prevalence, Risk Factors, and Relationship to Arterial Stiffness in the Treatment Options for Type 2 Diabetes in Adolescents and Youth (TODAY) Study " Diabetes Care. 2019 Nov ; 42 (11) : 2143-2150.
Pubmed PMID: 31501226.
Bacha F, El Ghormli L, Arslanian S, Zeitler P, Laffel LM, Levitt Katz LE, Gandica R, Chang NT, Sprague JE, Macleish SA. " Predictors of response to insulin therapy in youth with poorly-controlled type 2 diabetes in the TODAY trial " Pediatr Diabetes. 2019 Nov ; 20 (7) : 871-879.
Pubmed PMID: 31418516.
Bacha F, Bartz SK, Tomsa A, Sharma S. " Free Vitamin D: Relationship to Insulin Sensitivity and Vascular Health in Youth " J Pediatr. 2019 Sep 1; 212 : 28-34.
Pubmed PMID: 31201030.
Bacha F. " FDA approval of GLP-1 receptor agonist (liraglutide) for use in children " Lancet Child Adolesc Health. 2019 Jul 22; 3 (9) : 595-597.
Pubmed PMID: 31345736.
Kim JY, Bacha F, Tfayli H, Michaliszyn SF, Yousuf S, Arslanian S. " Adipose Tissue Insulin Resistance in Youth on the Spectrum From Normal Weight to Obese and From Normal Glucose Tolerance to Impaired Glucose Tolerance to Type 2 Diabetes " Diabetes Care. 2019 Feb 1; 42 (2) : 265-272.
Pubmed PMID: 30455334.
Arslanian S, El Ghormli L, Young Kim J, Bacha F, Chan C, Ismail HM, Levitt Katz LE, Levitsky L, Tryggestad JB, White NH; TODAY Study Group. " The Shape of the Glucose Response Curve During an Oral Glucose Tolerance Test: Forerunner of Heightened Glycemic Failure Rates and Accelerated Decline in β-Cell Function in TODAY " Diabetes Care. 2019 Jan 1; 42 (1) : 164-172.
Pubmed PMID: 30455329.
Tamborlane WV, Chang P, Kollman C, Klingensmith GJ, Ruedy K, Gal RL, Van Name M, Bacha F, Willi S, Beck RW. " Eligibility for clinical trials is limited for youth with type 2 diabetes: Insights from the Pediatric Diabetes Consortium T2D Clinic Registry " Pediatric Diabetes Consortium. 2018 Dec 1; 19 (8) : 1379-1384.
Pubmed PMID: 30175440.
Arslanian S, Bacha F, Grey M, Marcus MD, White NH, Zeitler P. " Evaluation and Management of Youth-Onset Type 2 Diabetes: A Position Statement by the American Diabetes Association " Diabetes Care. 2017 Dec 1; 41 (12) : 2648-2668.
Pubmed PMID: 30425094.
Sjaarda L, Lee S, Tfayli H, Bacha F, Bertolet M, Arslanian S. " Measuring ß-Cell Function Relative to Insulin Sensitivity in Youth: Does the hyperglycemic clamp suffice? " Diabetes Care. 2013 Jun ; 36 (6) : 1607-12.
Pubmed PMID: 23275361.
Bacha F, Gungor N, Lee S, de Las Heras J, Arslanian S. " Indices of Insulin Secretion during a Liquid Mixed-Meal Test in Obese Youth with Diabetes. " J. Pediatr.. 2013 May ; 162 (5) : 924-9.
Pubmed PMID: 23290511.
Bacha F, Gungor N, Lee S, Arslanian SA. " Progressive deterioration of ß-cell function in obese youth with type 2 diabetes. " Pediatr Diabetes. 2013 Mar ; 14 (2) : 106-11.
Pubmed PMID: 22913617.
Sjaarda LA, Michaliszyn SF, Lee S, Tfayli H, Bacha F, Farchoukh L, Arslanian SA. " HbA1c Diagnostic Categories and ß-Cell Function Relative to Insulin Sensitivity in Overweight/Obese Adolescents. " Diabetes Care. 2012 Dec ; 35 (12) : 2559-63.
Pubmed PMID: 22912428.
Michaliszyn SF, Sjaarda LA, Mihalik SJ, Lee S, Bacha F, Chace DH, De Jesus VR, Vockley J, Arslanian SA. " Metabolomic Profiling of Amino Acids and ß-Cell Function Relative to Insulin Sensitivity in Youth. " J. Clin. Endocrinol. Metab.. 2012 Nov ; 97 (11) : E2119-24.
Pubmed PMID: 22977272.
Lee S, Bacha F, Hannon T, Kuk JL, Boesch C, Arslanian S. " Effects of aerobic versus resistance exercise without caloric restriction on abdominal fat, intrahepatic lipid, and insulin sensitivity in obese adolescent boys: a randomized, controlled trial. " Diabetes. 2012 Nov ; 61 (11) : 2787-95.
Pubmed PMID: 22751691.
Bacha F, Pyle L, Nadeau K, Cuttler L, Goland R, Haymond M, Levitsky L, Lynch J, Weinstock RS, White NH, Caprio S, Arslanian S. " Determinants of glycemic control in youth with type 2 diabetes at randomization in the TODAY study. " Pediatr Diabetes. 2012 Aug ; 13 (5) : 376-83.
Pubmed PMID: 22332798.
Sjaarda LG, Bacha F, Lee S, Tfayli H, Andreatta E, Arslanian S. " Oral disposition index in obese youth from normal to prediabetes to diabetes: relationship to clamp disposition index. " J. Pediatr.. 2012 Jul ; 161 (1) : 51-7.
Pubmed PMID: 22325254.
Bacha F, Gungor N, Lee S, Arslanian SA. " Type 2 diabetes in youth: are there racial differences in ß-cell responsiveness relative to insulin sensitivity? " Pediatr Diabetes. 2012 May ; 13 (3) : 259-65.
Pubmed PMID: 21933317.
Mihalik SJ, Michaliszyn SF, de Las Heras J, Bacha F, Lee S, Chace DH, Dejesus VR, Vockley J, Arslanian SA. " Metabolomic Profiling of Fatty Acid and Amino Acid Metabolism in Youth With Obesity and Type 2 Diabetes: Evidence for enhanced mitochondrial oxidation. " Diabetes Care. 2012 Mar ; 35 (3) : 605-11.
Pubmed PMID: 22266733.
De Las Heras J, Lee S, Bacha F, Tfayli H, Arslanian S. " Cross-Sectional Association between Blood Pressure, in vivo Insulin Sensitivity and Adiponectin in Overweight Adolescents. " Horm Res Paediatr. 2011 ; 76 (6) : 379-85.
Pubmed PMID: 21968570.
Tfayli H, Jung Lee S, Bacha F, Arslanian S. " One-hour plasma glucose concentration during the OGTT: what does it tell about ß-cell function relative to insulin sensitivity in overweight/obese children? " Pediatr Diabetes. 2011 Sep ; 12 (6) : 572-9.
Pubmed PMID: 21466647.
Burns SF, Bacha F, Lee SJ, Tfayli H, Gungor N, Arslanian SA. " Declining {beta}-Cell Function Relative to Insulin Sensitivity With Escalating OGTT 2-h Glucose Concentrations in the Nondiabetic Through the Diabetic Range in Overweight Youth. " Diabetes Care. 2011 Sep ; 34 (9) : 2033-40.
Pubmed PMID: 21750275.
George L, Bacha F, Lee S, Tfayli H, Andreatta E, Arslanian S. " Surrogate Estimates of Insulin Sensitivity in Obese Youth along the Spectrum of Glucose Tolerance from Normal to Prediabetes to Diabetes. " J. Clin. Endocrinol. Metab.. 2011 Jul ; 96 (7) : 2136-45.
Pubmed PMID: 21508130.
Libman IM, Barinas-Mitchell E, Marcovina S, Bacha F, Hannon T, Tfayli H, Lee SJ, Bansal S, Robertson R, Arslanian S. " ß-cell autoimmunity in overweight non-diabetic youth: any implications? " Pediatr Diabetes. 2011 May ; 12 (3) : 207-11.
Pubmed PMID: 21518410.
Bacha F, Lee S, Gungor N, Arslanian SA. " From Pre-Diabetes to Type 2 Diabetes in Obese Youth: Pathophysiological characteristics along the spectrum of glucose dysregulation. " Diabetes Care. 2010 Oct ; 33 (10) : 2225-31.
Pubmed PMID: 20592052.
Tfayli H, Bacha F, Gungor N, Arslanian S. " Islet Cell Antibody-Positive Versus -Negative Phenotypic Type 2 Diabetes in Youth: Does the oral glucose tolerance test distinguish between the two? " Diabetes Care. 2010 Mar ; 33 (3) : 632-8.
Pubmed PMID: 20028940.
Tfayli H, Bacha F, Gungor N, Arslanian S. " Phenotypic type 2 diabetes in obese youth: insulin sensitivity and secretion in islet cell antibody-negative versus -positive patients. " Diabetes. 2009 Mar ; 58 (3) : 738-44.
Pubmed PMID: 19073767.
Bacha F, Gungor N, Lee S, Arslanian SA. " In vivo insulin sensitivity and secretion in obese youth: what are the differences between normal glucose tolerance, impaired glucose tolerance, and type 2 diabetes? " Diabetes Care. 2009 Jan ; 32 (1) : 100-5.
Pubmed PMID: 18835946.
Hannon TS, Bacha F, Lin Y, Arslanian SA. " Hyperinsulinemia in African-American adolescents compared with their American white peers despite similar insulin sensitivity: a reflection of upregulated beta-cell function? " Diabetes Care. 2008 Jul ; 31 (7) : 1445-7.
Pubmed PMID: 18417751.
Bacha F, Gungor N, Arslanian SA. " Measures of beta-cell function during the oral glucose tolerance test, liquid mixed-meal test, and hyperglycemic clamp test. " J. Pediatr.. 2008 May ; 152 (5) : 618-21.
Pubmed PMID: 18410762.
Lee S, Bacha F, Gungor N, Arslanian S. " Comparison of different definitions of pediatric metabolic syndrome: relation to abdominal adiposity, insulin resistance, adiponectin, and inflammatory biomarkers. " J. Pediatr.. 2008 Feb ; 152 (2) : 177-84.
Pubmed PMID: 18206686.
Lee S, Gungor N, Bacha F, Arslanian S. " Insulin resistance: link to the components of the metabolic syndrome and biomarkers of endothelial dysfunction in youth. " Diabetes Care. 2007 Aug ; 30 (8) : 2091-7.
Pubmed PMID: 17475936.
Lee S, Bacha F, Arslanian SA. " Waist circumference, blood pressure, and lipid components of the metabolic syndrome. " J. Pediatr.. 2006 Dec ; 149 (6) : 809-16.
Pubmed PMID: 17137898.
Hannon TS, Bacha F, Lee SJ, Janosky J, Arslanian SA. " Use of markers of dyslipidemia to identify overweight youth with insulin resistance. " Pediatr Diabetes. 2006 Oct ; 7 (5) : 260-6.
Pubmed PMID: 17054447.
Lee S, Bacha F, Gungor N, Arslanian SA. " Cardiorespiratory fitness in youth: relationship to insulin sensitivity and beta-cell function. " Obesity (Silver Spring). 2006 Sep ; 14 (9) : 1579-85.
Pubmed PMID: 17030969.
Bacha F, Arslanian SA. " Ghrelin and peptide YY in youth: are there race-related differences? " J. Clin. Endocrinol. Metab.. 2006 Aug ; 91 (8) : 3117-22.
Pubmed PMID: 16720664.
Bacha F, Saad R, Gungor N, Arslanian SA. " Are obesity-related metabolic risk factors modulated by the degree of insulin resistance in adolescents? " Diabetes Care. 2006 Jul ; 29 (7) : 1599-604.
Pubmed PMID: 16801585.
Lee S, Bacha F, Gungor N, Arslanian SA. " Waist circumference is an independent predictor of insulin resistance in black and white youths. " J. Pediatr.. 2006 Feb ; 148 (2) : 188-94.
Pubmed PMID: 16492427.
Lee S, Bacha F, Gungor N, Arslanian SA. " Racial differences in adiponectin in youth: relationship to visceral fat and insulin sensitivity. " Diabetes Care. 2006 Jan ; 29 (1) : 51-6.
Pubmed PMID: 16373895.
Gungor N, Hannon T, Libman I, Bacha F, Arslanian S. " Type 2 diabetes mellitus in youth: the complete picture to date. " Pediatr. Clin. North Am.. 2005 Dec ; 52 (6) : 1579-609.
Pubmed PMID: 16301084.
Bacha F, Saad R, Gungor N, Arslanian SA. " Does adiponectin explain the lower insulin sensitivity and hyperinsulinemia of African-American children? " Pediatr Diabetes. 2005 Jun ; 6 (2) : 100-2.
Pubmed PMID: 15963038.
Bacha F, Arslanian SA. " Ghrelin suppression in overweight children: a manifestation of insulin resistance? " J. Clin. Endocrinol. Metab.. 2005 May ; 90 (5) : 2725-30.
Pubmed PMID: 15728212.
Gungor N, Bacha F, Saad R, Janosky J, Arslanian S. " Youth type 2 diabetes: insulin resistance, beta-cell failure, or both? " Diabetes Care. 2005 Mar ; 28 (3) : 638-44.
Pubmed PMID: 15735201.
Arslanian SA, Bacha F, Saad R, Gungor N. " Family history of type 2 diabetes is associated with decreased insulin sensitivity and an impaired balance between insulin sensitivity and insulin secretion in white youth. " Diabetes Care. 2005 Jan ; 28 (1) : 115-9.
Pubmed PMID: 15616243.
Bacha F, Saad R, Gungor N, Arslanian SA. " Adiponectin in youth: relationship to visceral adiposity, insulin sensitivity, and beta-cell function. " Diabetes Care. 2004 Feb ; 27 (2) : 547-52.
Pubmed PMID: 14747242.
Bacha F, Saad R, Gungor N, Janosky J, Arslanian SA. " Obesity, regional fat distribution, and syndrome X in obese black versus white adolescents: race differential in diabetogenic and atherogenic risk factors. " J. Clin. Endocrinol. Metab.. 2003 Jun ; 88 (6) : 2534-40.
Pubmed PMID: 12788850.
Bacha F, Hoo JJ. " New syndrome characterized by sparse hair, prominent nose, small mouth, micrognathia, cleft palate, crumpled upper helices, digit anomaly, and mild developmental delay. " Am. J. Med. Genet.. 2001 Jun 1; 101 (1) : 70-3.
Pubmed PMID: 11343342.
Bacha F, Domachowske JB. " Pasteurella multocida pneumonia in an adolescent with Duchenne's muscular dystrophy following exposure to his helper dog. " Clin Pediatr (Phila). 2001 Mar ; 40 (3) : 159-61.
Pubmed PMID: 11307962.
Amis T, Di Somma E, Bacha F, Wheatley J. " Influence of intra-oral maxillary sports mouthguards on the airflow dynamics of oral breathing. " Med Sci Sports Exerc. 2000 Feb ; 32 (2) : 284-90.
Pubmed PMID: 10694108.

Projects

Determinants of Subclinical Coronary Atherosclerosis and Endothelial Dysfunction in Youth.: USDA/ARS- Thrasher Research Fund
Determinants of Endothelial Dysfunction in Obese Youth with and without Type 2 diabetes: USDA/ARS; This project evaluated the effects of obesity and type 2 diabetes on vascular health and its determinants in youth.
Treatment Options for Type 2 Diabetes in Adolescents and Youth (TODAY): NIh-NIDDK
T1D Exchange - A Randomized Trial of Metformin as Adjunct Therapy for Overweight
Pediatric Diabetes Consortium for Type 2 Diabetes
Ectopic Hepatic Fat in Hispanic Youth: Risk for Endothelial Dysfunction
Preeclampsia and Fetal Origins of Childhood Insulin Resistance and Risk for Type 2 Diabetes and Cardiovascular Disease.
Bone Health in Obese Youth with and without Type 2 diabetes: USDA/ARS (10/2019 - 09/2024); Investigate the effect of adiposity, adipokine dysregulation (the balance of circulating anti-inflammatory vs. proinflammatory factors) and vitamin D concentrations on bone microarchitecture (cortical porosity, trabecular thickness), bone biomarkers and endothelial function in youth with and without abnormalities in glucose metabolism.
Type 2 Diabetes and Bone Health in Youth: NIH-NICHD
Understanding and Targeting the Pathophysiology of Youth-onset Type 2 Diabetes: NIH-NIDDK