Positions

Associate Professor

Radiology
Baylor College of Medicine
Houston, TX, US

Addresses

1102 Bates Street (Office)

Suite 850
Houston, TX, 77030
United States
Phone: (832) 824-0866
tanifum@bcm.edu

1102 Bates Street (Lab)

Suite 850
Houston, TX, 77030
United States
Phone: (832) 824-0866
tanifum@bcm.edu

Websites

Selected Publications

• Tanifum EA, Gilbertson SR. " Design, synthesis, and diversification of 5,5-dimethyl cyclohexen-1,4-dione library. " J Comb Chem. 2010 May 10; 12 (3) : 318-20.
  Pubmed PMID: 20387791.
• Tanifum EA, Dasgupta I, Srivastava M, Bhavane RC, Sun L, Berridge J, Pourgarzham H, Kamath R, Espinosa G, Cook SC, Eriksen JL, Annapragada A. " Intravenous Delivery of Targeted Liposomes to Amyloid-ß Pathology in APP/PSEN1 Transgenic Mice. " PLoS ONE. 2012 ; 7 (10) : e48515.
  Pubmed PMID: 23119043.
• Feng G, Tanifum EA, Adams H, Hengge AC, Williams NH. " Mechanism and transition state structure of aryl methylphosphonate esters doubly coordinated to a dinuclear cobalt(III) center. " J. Am. Chem. Soc.. 2009 Sep 9; 131 (35) : 12771-9.
  Pubmed PMID: 19673521.
• McWhirter C, Lund EA, Tanifum EA, Feng G, Sheikh QI, Hengge AC, Williams NH. " Mechanistic study of protein phosphatase-1 (PP1), a catalytically promiscuous enzyme. " J. Am. Chem. Soc.. 2008 Oct 15; 130 (41) : 13673-82.
  Pubmed PMID: 18798625.
• Dasgupta I, Tanifum EA, Srivastava M, Phatak SS, Cavasotto CN, Analoui M, Annapragada A. " Non inflammatory boronate based glucose-responsive insulin delivery systems. " PLoS ONE. 2012 ; 7 (1) : e29585.
  Pubmed PMID: 22272238.
• Tanifum EA, Kots AY, Choi BK, Murad F, Gilbertson SR. " Novel pyridopyrimidine derivatives as inhibitors of stable toxin a (STa) induced cGMP synthesis. " Bioorg. Med. Chem. Lett.. 2009 Jun 1; 19 (11) : 3067-71.
  Pubmed PMID: 19409779.
• Hadler KS, Tanifum EA, Yip SH, Mitic N, Guddat LW, Jackson CJ, Gahan LR, Nguyen K, Carr PD, Ollis DL, Hengge AC, Larrabee JA, Schenk G. " Substrate-promoted formation of a catalytically competent binuclear center and regulation of reactivity in a glycerophosphodiesterase from Enterobacter aerogenes. " J. Am. Chem. Soc.. 2008 Oct 29; 130 (43) : 14129-38.
  Pubmed PMID: 18831553.
• Tomla C, Kamnaing P, Ayimele GA, Tanifum EA, Tsopmo A, Tane P, Ayafor JF, Connolly JD. " Three labdane diterpenoids from Aframomum sceptrum (Zingiberaceae). " Phytochemistry. 2002 May ; 60 (2) : 197-200.
  Pubmed PMID: 12009324.
• Kamnaing P, Tsopmo A, Tanifum EA, Tchuendem MH, Tane P, Ayafor JF, Sterner O, Rattendi D, Iwu MM, Schuster B, Bacchi C. " Trypanocidal diarylheptanoids from Aframomum letestuianum. " J. Nat. Prod.. 2003 Mar ; 66 (3) : 364-7.
  Pubmed PMID: 12662093.
• A dual target molecular magnetic resonance imaging probe for noninvasive profiling of pathologic alpha-synuclein and microgliosis in a mouse model of Parkinson's disease " 2024 ;
  Pubmed PMID: 39114484.
• Advances in nanoprobes for molecular MRI of Alzheimer's disease " 2024 ;
  Pubmed PMID: 38426638.
• Rational Design of a Self-Assembling High Performance Organic Nanofluorophore for Intraoperative NIR-II Image-Guided Tumor Resection of Oral Cancer " 2023 ;
  Pubmed PMID: 36721029.
• Nanoparticle Contrast-enhanced MRI for Visualization of Retroplacental Clear Space Disruption in a Mouse Model of Placental Accreta Spectrum (PAS) " 2023 ;
  Pubmed PMID: 36167627.
• A surrogate marker for very early-stage tau pathology is detectable by molecular magnetic resonance imaging " 2022 ;
  Pubmed PMID: 35910789.
• Nanoprobes for Computed Tomography and Magnetic Resonance Imaging in Atherosclerosis Research " 2022 ;
  Pubmed PMID: 35238003.
• 1-Indanone and 1,3-indandione Derivatives as Ligands for Misfolded a-Synuclein Aggregates " 2022 ;
  Pubmed PMID: 34704363.
• Early Detection of Aortic Degeneration in a Mouse Model of Sporadic Aortic Aneurysm and Dissection Using Nanoparticle Contrast-Enhanced Computed Tomography " 2021 ;
  Pubmed PMID: 33535789.
• Nanoparticle Contrast-enhanced T1-Mapping Enables Estimation of Placental Fractional Blood Volume in a Pregnant Mouse Model " 2019 ;
  Pubmed PMID: 31822711.
• Pre-clinical dose-ranging efficacy, pharmacokinetics, tissue biodistribution, and toxicity of a targeted contrast agent for MRI of amyloid deposition in Alzheimer's disease " 2020 ;
  Pubmed PMID: 32999398.
• Pre-clinical magnetic resonance imaging of retroplacental clear space throughout gestation. " 2019 ;
  Pubmed PMID: 30827350.
• A Hyperfluorinated Hydrophilic Molecule for Aqueous 19F MRI Contrast Media " 2018 ;
  Pubmed PMID: 30538612.
• Magnetic Resonance Imaging of Atherosclerotic Plaque at Clinically Relevant Field Strengths (1T) by Targeting the Integrin α4β1 " 2018 ;
  Pubmed PMID: 29487319.
• Hydrophilic fluorinated molecules for spectral 19F MRI " 2018 ;
  Pubmed PMID: 29440665.
• A Novel Liposomal Nanoparticle for the Imaging of Amyloid Plaque by Magnetic Resonance Imaging " 2016 ;
  Pubmed PMID: 27031484.
• Cerebral vascular leak in a mouse model of amyloid neuropathology. " 2014 ;
  Pubmed PMID: 25052555.