Christopher Ward, Ph.D.

Associate Professor/Director Mouse Metabolism and Phenotyping Core

(713) 798-5040

Email

christopher.ward@bcm.edu

Positions

Associate Professor/Director Mouse Metabolism and Phenotyping Core: Integrative Physiology/Advanced Technology Cores
Baylor College of Medicine
Houston, TX, US

Addresses

Mouse Metabolism and Phenotyping Core (Lab): One Baylor Plaza
T001
Houston, TX, 77030
United States
Phone: (713) 798-5040
christopher.ward@bcm.edu
MMPC

Mouse Metabolism and Phenotyping Core (Office): One Baylor Plaza
T001
Houston, TX, 77030
United States
Phone: (713) 798-5040
christopher.ward@bcm.edu
MMPC

Education

B.S. from Ferris State University: 05/2005 - Big Rapids, Michigan, United States; Biotechnology

Ph.D. from Baylor College of Medicine: 01/2013 - Houston, Texas, United States; Molecular and Human Genetics

Professional Interests

Rett Syndrome
Autism Spectrum Disorder
Animal Behavior and Physiology
Data Analysis and Management
Phenotyping

Professional Statement

The Mouse Metabolism and Phenotyping Core provides service, consultation, and access to multiple modalities of whole animal and organ system phenotyping. As part of Baylor College of Medicine's Advanced Technology Cores, we serve as a resource to investigators at BCM, the TMC, as well as the broader scientific community.

Selected Publications

McGraw CM, Ward CS, Samaco RC. " Genetic rodent models of brain disorders: Perspectives on experimental approaches and therapeutic strategies. " Am J Med Genet C Semin Med Genet.. 2017 Sep ; 175 (3) : 368-379.
Pubmed PMID: 28910526.
Ward CS, Huang TW, Herrera JA, Samaco RC, Pitcher MR, Herron A, Skinner SA, Kaufmann WE, Glaze DG, Percy AK, Neul JL. " Loss of MeCP2 Causes Urological Dysfunction and Contributes to Death by Kidney Failure in Mouse Models of Rett Syndrome. " PLoS One. 2016 Nov ; 11 (11)
Pubmed PMID: 27828991.
Veeraragavan S, Wan YW, Connolly DR, Hamilton SM, Ward CS, Soriano S, Pitcher MR, McGraw CM, Huang SG, Green JR, Yuva LA, Liang AJ, Neul JL, Yasui DH, LaSalle JM, Liu Z, Paylor R, Samaco RC. " Loss of MeCP2 in the rat models regression, impaired sociability and transcriptional deficits of Rett syndrome. " Hum Mol Genet. 2016 Aug ; 25 (15) : 3284-3302.
Pubmed PMID: 27365498.
Ward CS, Arvide EM, Huang TW, Yoo J, Noebels JL, Neul JL. " MeCP2 is critical within HoxB1-derived tissues of mice for normal lifespan. " J Neurosci. 2011 Jul ; 31 (28)
Pubmed PMID: 21753013.
Herrera JA, Ward CS, Wehrens XH, Neul JL. " Methyl-CpG binding-protein 2 function in cholinergic neurons mediates cardiac arrhythmogenesis. " Hum Mol Genet. 2016 Nov ; 15 (25) : 4983-4995.
Pubmed PMID: 28159985.
Wang J, Wegener JE, Huang TW, Sripathy S, De Jesus-Cortes H, Xu P, Tran S, Knobbe W, Leko V, Britt J, Starwalt R, McDaniel L, Ward CS, Parra D, Newcomb B, Lao U, Nourigat C, Flowers DA, Cullen S, Jorstad NL, Yang Y, Glaskova L, Vingeau S,...Pieper AA. " Wild-type microglia do not reverse pathology in mouse models of Rett syndrome. " Nature. 2015 May ; 521 (7552)
Pubmed PMID: 25993969.

Projects

Knockout Mouse Phenotyping Project (KOMP2): NIH; Baylor College of Medicine; A collaboration with the International Mouse Phenotyping Consortium (IMPC) to undertake standardized phenotyping of 20,000 knockout mouse strains.

Memberships

Society For Neuroscience: Member

American Physiological Society: Member

Association of Biomolecular Resource Facilities: Member