Candy L Smith, Ph.D.

Assistant Professor

Email

candys@bcm.edu

Positions

Assistant Professor: Psychiatry & Behav Sciences
Baylor College of Medicine
Houston, TX, US

Addresses

Veterans Affairs Medical Centr (Office): Room: VAMC-PSYCH
Houston, TX, 77280
United States

Education

Advanced Training from Veterans Affairs Medical Center (Houston): 01/2003 - Houston, TX, United States

Ph.D. from University Of Arkansas: 01/2002 - Fayetteville, AR, United States

M.A. from University Of Arkansas: 01/1998 - Fayetteville, AR, United States

B.A. from Washburn University: 01/1996 - Topeka,, KS, United States

Websites

VIICTR Publications List

Selected Publications

Chen W, Bardhan R, Bartels M, Perez-Torres C, Pautler RG, Halas NJ, Joshi A. " A molecularly targeted theranostic probe for ovarian cancer. " Mol. Cancer Ther.. 2010 Apr ; 9 (4) : 1028-38.
Pubmed PMID: 20371708.
Ma T, Hoeffer CA, Wong H, Massaad CA, Zhou P, Iadecola C, Murphy MP, Pautler RG, Klann E. " Amyloid {beta}-Induced Impairments in Hippocampal Synaptic Plasticity Are Rescued by Decreasing Mitochondrial Superoxide. " J. Neurosci.. 2011 Apr 13; 31 (15) : 5589-95.
Pubmed PMID: 21490199.
Bitner BR, Marcano DC, Berlin JM, Fabian RH, Cherian L, Culver JC, Dickinson ME, Robertson CS, Pautler RG, Kent TA, Tour JM. " Antioxidant carbon particles improve cerebrovascular dysfunction following traumatic brain injury. " ACS Nano. 2012 Sep 25; 6 (9) : 8007-14.
Pubmed PMID: 22866916.
Serrano F, Deshazer M, Smith KD, Ananta JS, Wilson LJ, Pautler RG. " Assessing transneuronal dysfunction utilizing manganese-enhanced MRI (MEMRI). " Magn Reson Med. 2008 Jul ; 60 (1) : 169-75.
Pubmed PMID: 18581360.
Pautler RG. " Biological applications of manganese-enhanced magnetic resonance imaging. " Methods Mol. Med.. 2006 ; 124 : 365-86.
Pubmed PMID: 16506430.
Peethumnongsin E, Yang L, Kallhoff-Muñoz V, Hu L, Takashima A, Pautler RG, Zheng H. " Convergence of presenilin- and tau-mediated pathways on axonal trafficking and neuronal function. " J. Neurosci.. 2010 Oct 6; 30 (40) : 13409-18.
Pubmed PMID: 20926667.
Hu L, Sun Y, Villasana LE, Paylor R, Klann E, Pautler RG. " Early changes in the apparent diffusion coefficient (ADC) in a mouse model of Sandhoff's disease occur prior to disease symptoms and behavioral deficits. " Magn Reson Med. 2009 Nov ; 62 (5) : 1175-84.
Pubmed PMID: 19780154.
Kallhoff-Munoz V, Hu L, Chen X, Pautler RG, Zheng H. " Genetic dissection of gamma-secretase-dependent and -independent functions of presenilin in regulating neuronal cell cycle and cell death. " J. Neurosci.. 2008 Oct 29; 28 (44) : 11421-31.
Pubmed PMID: 18971484.
Sharma R, Buras E, Terashima T, Serrano F, Massaad CA, Hu L, Bitner B, Inoue T, Chan L, Pautler RG. " Hyperglycemia induces oxidative stress and impairs axonal transport rates in mice. " PLoS ONE. 2010 ; 5 (10) : e13463.
Pubmed PMID: 20976160.
Lian H, Shim DJ, Gaddam SS, Rodriguez-Rivera J, Bitner BR, Pautler RG, Robertson CS, Zheng H. " I?Ba deficiency in brain leads to elevated basal neuroinflammation and attenuated response following traumatic brain injury: implications for functional recovery. " Mol Neurodegener. 2012 ; 7 : 47.
Pubmed PMID: 22992283.
Williams K, Koyama T, Schulz D, Kaluza GL, Pautler RG, Weisbrodt N, Conner ME. " Use of fluoroscopy to study in vivo motility in mouse pups. " J. Pediatr. Gastroenterol. Nutr.. 2011 Jun ; 52 (6) : 679-85.
Pubmed PMID: 21593642.
Pautler RG, Fraser SE. " The year(s) of the contrast agent - micro-MRI in the new millennium. " Curr. Opin. Immunol.. 2003 Aug ; 15 (4) : 385-92.
Pubmed PMID: 12900268.
Pautler RG, Koretsky AP. " Tracing odor-induced activation in the olfactory bulbs of mice using manganese-enhanced magnetic resonance imaging. " Neuroimage. 2002 Jun ; 16 (2) : 441-8.
Pubmed PMID: 12030829.
Ghugre NR, Martin M, Scadeng M, Ruffins S, Hiltner T, Pautler R, Waters C, Readhead C, Jacobs R, Wood JC. " Superiority of 3D wavelet-packet denoising in MR microscopy. " Magn Reson Imaging. 2003 Oct ; 21 (8) : 913-21.
Pubmed PMID: 14599542.
Tyszka JM, Readhead C, Bearer EL, Pautler RG, Jacobs RE. " Statistical diffusion tensor histology reveals regional dysmyelination effects in the shiverer mouse mutant. " Neuroimage. 2006 Feb 15; 29 (4) : 1058-65.
Pubmed PMID: 16213163.
Hassan AA, Chan BT, Tran LA, Hartman KB, Ananta JS, Mackeyev Y, Hu L, Pautler RG, Wilson LJ, Lee AV. " Serine-derivatized gadonanotubes as magnetic nanoprobes for intracellular labeling. " Contrast Media Mol Imaging. 2010 Jan ; 5 (1) : 34-8.
Pubmed PMID: 20101755.
Smith KD, Paylor R, Pautler RG. " R-flurbiprofen improves axonal transport in the Tg2576 mouse model of Alzheimer's Disease as determined by MEMRI. " Magn Reson Med. 2011 May ; 65 (5) : 1423-9.
Pubmed PMID: 21500269.
Massaad CA, Washington TM, Pautler RG, Klann E. " Overexpression of SOD-2 reduces hippocampal superoxide and prevents memory deficits in a mouse model of Alzheimer's disease. " Proc. Natl. Acad. Sci. U.S.A.. 2009 Aug 11; 106 (32) : 13576-81.
Pubmed PMID: 19666610.
Serrano F, Chang A, Hernandez C, Pautler RG, Sweatt JD, Klann E. " NADPH oxidase mediates beta-amyloid peptide-induced activation of ERK in hippocampal organotypic cultures. " Mol Brain. 2009 ; 2 (1) : 31.
Pubmed PMID: 19804648.
Pautler RG. " Mouse MRI: concepts and applications in physiology. " 2004 Aug ; 19 : 168-75.
Pubmed PMID: 15304630.
Massaad CA, Pautler RG, Klann E. " Mitochondrial superoxide: a key player in Alzheimer's disease. " Aging (Albany NY). 2009 ; 1 (9) : 758-61.
Pubmed PMID: 20157564.
Kannankeril PJ, Mitchell BM, Goonasekera SA, Chelu MG, Zhang W, Sood S, Kearney DL, Danila CI, De Biasi M, Wehrens XH, Pautler RG, Roden DM, Taffet GE, Dirksen RT, Anderson ME, Hamilton SL. " Mice with the R176Q cardiac ryanodine receptor mutation exhibit catecholamine-induced ventricular tachycardia and cardiomyopathy. " Proc. Natl. Acad. Sci. U.S.A.. 2006 Aug 8; 103 (32) : 12179-84.
Pubmed PMID: 16873551.
Sano M, Izumi Y, Helenius K, Asakura M, Rossi DJ, Xie M, Taffet G, Hu L, Pautler RG, Wilson CR, Boudina S, Abel ED, Taegtmeyer H, Scaglia F, Graham BH, Kralli A, Shimizu N, Tanaka H, Mäkelä TP, Schneider MD. " Ménage-à-trois 1 is critical for the transcriptional function of PPARgamma coactivator 1. " Cell Metab.. 2007 Feb ; 5 (2) : 129-42.
Pubmed PMID: 17276355.
Massaad CA, Amin SK, Hu L, Mei Y, Klann E, Pautler RG. " Mitochondrial superoxide contributes to blood flow and axonal transport deficits in the Tg2576 mouse model of Alzheimer's disease. " PLoS ONE. 2010 ; 5 (5) : e10561.
Pubmed PMID: 20479943.
Hu TC, Pautler RG, MacGowan GA, Koretsky AP. " Manganese-enhanced MRI of mouse heart during changes in inotropy. " Magn Reson Med. 2001 Nov ; 46 (5) : 884-90.
Pubmed PMID: 11675639.
Massaad CA, Pautler RG. " Manganese-Enhanced Magnetic Resonance Imaging (MEMRI). " Methods Mol. Biol.. 2011 ; 711 : 145-74.
Pubmed PMID: 21279601.
Bitner BR, Brink DC, Mathew LC, Pautler RG, Robertson CS. " Impact of arginase II on CBF in experimental cortical impact injury in mice using MRI. " J. Cereb. Blood Flow Metab.. 2010 Jun ; 30 (6) : 1105-9.
Pubmed PMID: 20372170.
Pérez-Torres CJ, Massaad CA, Hilsenbeck SG, Serrano F, Pautler RG. " In vitro and in vivo magnetic resonance imaging (MRI) detection of GFP through magnetization transfer contrast (MTC). " Neuroimage. 2010 Apr 1; 50 (2) : 375-82.
Pubmed PMID: 20060482.
Smith KD, Kallhoff V, Zheng H, Pautler RG. " In vivo axonal transport rates decrease in a mouse model of Alzheimer's disease. " Neuroimage. 2007 May 1; 35 (4) : 1401-8.
Pubmed PMID: 17369054.
Pautler RG, Silva AC, Koretsky AP. " In vivo neuronal tract tracing using manganese-enhanced magnetic resonance imaging. " Magn Reson Med. 1998 Nov ; 40 (5) : 740-8.
Pubmed PMID: 9797158.
Pautler RG, Mongeau R, Jacobs RE. " In vivo trans-synaptic tract tracing from the murine striatum and amygdala utilizing manganese enhanced MRI (MEMRI). " Magn Reson Med. 2003 Jul ; 50 (1) : 33-9.
Pubmed PMID: 12815676.
Pautler RG. " In vivo, trans-synaptic tract-tracing utilizing manganese-enhanced magnetic resonance imaging (MEMRI). " NMR Biomed. 2004 Dec ; 17 (8) : 595-601.
Pubmed PMID: 15761948.
Inoue T, Majid T, Pautler RG. " Manganese enhanced MRI (MEMRI): neurophysiological applications. " Rev Neurosci. 2011 ; 22 (6) : 675-94.
Pubmed PMID: 22098448.