Bruna Corradetti

Corradetti

Bruna Corradetti, PhD

Assistant Professor

Positions

Assistant Professor
Center for Precision Environmental Health
Baylor College of Medicine

Education

PhD from Polytechnic University of Marche
02/2012 - Ancona, Italy
MSc from Polytechnic University of Marche
07/2008 - Ancona, Italy
BSc from Polytechnic University of Marche
03/2005 - Ancona, Italy

Videos

TEDx Talk
The power of resilience in science

Selected Publications

  • Corradetti B, Correani A, Romaldini A, Marini MG, Bizzaro D, Perrini C, Cremonesi F, Lange-Consiglio A. " Amniotic membrane-derived mesenchymal cells and their conditioned media: potential candidates for uterine regenerative therapy in the horse.. " PLoS One. 2014 ; 9: : e111324.
  • Pisano S, Lenna S, Healey GD, Meeks L, Jimenez JS, Velazquez O, Gonzalez D, Conlan RS, Corradetti B.. " Assessment of the immune landscapes of advanced ovarian cancer in an optimized in vivo model.. " Clinical and Translational Medicine. 2021 ; 10 : e551.
  • Corradetti B, Vaiasicca S, Mantovani M, Virgili E, Bonucci M, Hammarberg Ferri I. " Bioactive Immunomodulatory Compounds: A Novel Combinatorial Strategy for Integrated Medicine in Oncology?. " Integr Cancer Ther. ; 18 : 1534735419866908..
  • Villarreal RA, Cooke JP, Corradetti B.. " Biomimetic and immunomodulatory therapeutics as an alternative to natural exosomes for vascular and cardiac applications.. " Nanomedicine: Nanotechnology, Biology and Medicine.. 2021 ; 35 : 102385..

Funding

Exosomes as tools for cell-to-cell communication during the inflammatory process
#663830 – SU185
(07/01/2018 - 02/28/2022)
Grant funding from European Commission - COFUND Marie Skłodowska-Curie Action Fellowship
Transdifferentiating Fibroblasts to vascular endothelial cells for the treatment of chronic wounds
#18220004
(02/01/2020 - 01/31/2021)
Grant funding from George and Angelina Kostas Foundation
Harnessing he potential of dendritic cells-derived exosomes as tools for immunotherapy in ovarian cancer
(03/22/2019 - 12/31/2023)
Grant funding from Golfers Against Cancer Foundation
Engineering RNA-based conductive patches for the treatment of endotheliopathy-associated chronic wounds
Grant funding from George and Angelina Kostas Foundation
A Local Immunoactive Patch for the Treatment of Chronic Wounds
Grant funding from US Army - Peer Reviewed Medical Research Program Discovery Award

Intellectual Property

Exosomal vaccines as co-adjuvant treatment of patients with advanced ovarian cancer.
Method Patent #OTT202112 (Pending)
Invention disclosure filed at Houston Methodist Research Institute
Co Inventors: Simone Pisano

Skills

mRNA-enhanced therapeutics for regenerative medicine
Stem cell-based therapeutics
Immunotherapy and immunomodulation
Exosomes and exosome mimetics for degenerative disorders
Exosomal vaccines against cancer recurrence
Mouse models

Languages

Italian, Spanish

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