Email

Positions

Associate Professor

Psychiatry and Behavioral Sciences
Baylor College of Medicine
Houston, TX, US

Education

PhD from The New School for Social Research

New York

Clinical Psychology

Selected Publications

• O’Brien B, Lijffijt M, Wells A, Swann AC, Mathew SJ.. " The Impact of Childhood Maltreatment on Intravenous Ketamine Outcomes in Adult Patients with Treatment-Resistant Depression " Pharmaceuticals (Basel). 2019 Sep 11; 12 (3)
  Pubmed PMID: 31514448.
• O'Brien B, Shrestha S, Stanley MA, Pargament KI, Cummings J, Kunik ME, Fletcher TL, Cortes J, Ramsey D, Amspoker AB. " Positive and negative religious coping as predictors of distress among minority older adults. " Int J Geriatr Psychiatry. 2019 Jan ; 34 (1) : 54-89.
  Pubmed PMID: 30375027.
• O’Brien B, Green CE, Al-Jurdi R, Chang L, Lijffijt M, Iqbal S, Iqbal T, Swann AC, Mathew SJ.. " Bayesian adaptive randomization trial of intravenous ketamine for veterans " Contemp Clin Trials Commun. 2019 Aug 21; 16
  Pubmed PMID: 31508531.
• . Lijffijt, M, O’Brien, B, Salas, R, Mathew, SJ, Swann, AC.. " Interactions of Immediate and Long-term Action Regulation in Course and Complications of Bipolar Disorder " Philos Trans R Soc Lond B Biol Sci. 2019 Feb 18; 374 (1766)
  Pubmed PMID: 30966917.
• Lifjjijt M. Green C, Balderston N, Iqbal t, Atkinson m, Vo-Le B, Vo-Le B, O'Brien B, Grillon c Swann AC, Mathew SJ. " A proof-of-mechanism study to test effects of the NMDA receptor antagonist lanicemine on behavioral sensitization in individuals with symptoms of PTSD " Front. Psychaitry. 2019 ;
• Swann AC, Lijffijt M, O'Brien B, Mathew SJ. " Impulsivity and Suicidal Behavior. " Curr Top Behav Neurosci.. 2020 May 30;
  Pubmed PMID: 32472429.
• O'Brien B, Lijffijt M, Lee J, Kim YS, Walls A, Murphy N, Ramakrishnan N, Swann AC, Mathew SJ. " Distinct trajectories of antidepressant response to intravenous ketamine " J Affect Disord. 2021 May ;
  Pubmed PMID: 33770540.
• An Update on Community Ketamine Practices. " Am J Psych. ;
• O'Brien B, Lee J, Kim S, Nandra G, Pannu P, Swann AC, Murphy N, Tamman AJF, Amarneh D, Lijffijt M, Averill LA, Mathew SJ.. " Replication of distinct trajectories of antidepressant response to intravenous ketamine " J Affect Disord.. 2023 Jan ; 321 : 140-146.
  Pubmed PMID: 36302492.

Funding

Investigating the safety and clinical efficacy of psilocybin-assisted therapy for the treatment of posttraumatic stress disorder among US Veterans: A Phase 2 RCT

(08/22/2022 - 12/31/2024)

Grant funding from State of Texas, HB1802, HHS