Barna Dudok, Ph.D.

Assistant Professor

(713) 798-2024

Email

barna.dudok@bcm.edu

Positions

Assistant Professor: Neurology
Baylor College of Medicine
Houston, Texas

Education

Postdoctoral Fellowship at Stanford University: Stanford, California

PhD from Semmelweis University: Budapest, Hungary; Neuroscience

Professional Statement

My research interest is focused on better understanding how GABAergic inhibitory interneurons shape circuit dynamics in healthy brains and in epilepsy. Our goal is to identify optimal targets for neuromodulatory intervention and develop cell type-specific strategies for inhibiting epilepsy.

Websites

Lab website

Dr. Dudok's Bibliography

Comprehensive list of publications and presentations

Selected Publications

Dudok B, Klein PM, Hwaun E, Lee BR, Yao Z, Fong O, et al.. " Alternating sources of perisomatic inhibition during behavior " Neuron. 2021 ; 109 (6) : 997-1012.
Pubmed PMID: 33529646.
Farrell JS, Colangeli R, Dong A, George AG, Addo-Osafo K, Kingsley PJ, et al.. " In vivo endocannabinoid dynamics at the timescale of physiological and pathological neural activity " Neuron. 2021 ; 109 (15) : 2398-403.
Pubmed PMID: 34352214.
Dudok B, Szoboszlay M, Paul A, Klein PM, Liao Z, Hwaun E, et al.. " Recruitment and inhibitory action of hippocampal axo-axonic cells during behavior " Neuron. 2021 ; 109 (23) : 3838-50.
Pubmed PMID: 34648750.
Dudok B, Klein PM, Soltesz I. " Toward understanding the diverse roles of perisomatic interneurons in epilepsy " Epilepsy Curr. 2022 ; 22 (1) : 54-60.
Pubmed PMID: 35233202.
Dong A, He K, Dudok B, Farrell JS, Guan W, Liput DJ, et al.. " A fluorescent sensor for spatiotemporally resolved imaging of endocannabinoid dynamics in vivo " Nat Biotechnol. 2022 ; 40 (5) : 787-98.
Pubmed PMID: 34764491.
Dudok B, Barna L, Ledri M, Szabo SI, Szabadits E, Pinter B, et al.. " Cell-specific STORM super-resolution imaging reveals nanoscale organization of cannabinoid signaling " Nat Neurosci. 2015 ; 18 (1) : 75-86.
Pubmed PMID: 25485758.
Dudok B, Soltesz I. " Imaging the endocannabinoid signaling system " J Neurosci Methods. 2022 ; 367 : 109451.
Pubmed PMID: 34921843.
Szabo GG, Farrell JS, Dudok B, Hou WH, Ortiz AL, Varga C, et al.. " Ripple-selective GABAergic projection cells in the hippocampus " Neuron. 2022 ; 110 (12) : 1959-77.
Pubmed PMID: 35489331.
Farrell JS, Lovett-Barron M, Klein PM, Sparks FT, Gschwind T, Ortiz AL, et al.. " Supramammillary regulation of locomotion and hippocampal activity " Science. 2021 ; 374 (6574) : 1492-6.
Pubmed PMID: 34914519.
Prokop S, Abranyi-Balogh P, Barti B, Vamosi M, Zoldi M, Barna L, et al.. " PharmacoSTORM nanoscale pharmacology reveals cariprazine binding on Islands of Calleja granule cells " Nat Commun. 2021 ; 12 (1) : 6505.
Pubmed PMID: 34764251.
Farrell JS, Colangeli R, Dudok B, Wolff MD, Nguyen SL, Jackson J, et al.. " In vivo assessment of mechanisms underlying the neurovascular basis of postictal amnesia " Sci Rep. 2020 ; 10 (1) : 14992.
Pubmed PMID: 32929133.
Lee SH, Dudok B, Parihar VK, Jung KM, Zoldi M, Kang YJ, et al.. " Neurophysiology of space travel: energetic solar particles cause cell type-specific plasticity of neurotransmission " Brain Struct Funct. 2017 ; 222 (5) : 2345-57.
Pubmed PMID: 27905022.
Barna L, Dudok B, Miczan V, Horvath A, Laszlo ZI, Katona I.. " Correlated confocal and super-resolution imaging by VividSTORM " Nat Protoc. 2016 ; 11 (1) : 163-83.
Pubmed PMID: 26716705.
Younts TJ, Monday HR, Dudok B, Klein ME, Jordan BA, Katona I, et al.. " Presynaptic protein synthesis is required for long-term plasticity of GABA release " Neuron. 2016 ; 92 (2) : 479-92.
Pubmed PMID: 27764673.
Lee SH, Ledri M, Toth B, Marchionni I, Henstridge CM, Dudok B, et al.. " Multiple forms of endocannabinoid and endovanilloid signaling regulate the tonic control of GABA release " J Neurosci. 2015 ; 35 (27) : 10039-57.
Pubmed PMID: 26157003.
Neuhofer D, Henstridge CM, Dudok B, Sepers M, Lassalle O, Katona I, et al.. " Functional and structural deficits at accumbens synapses in a mouse model of Fragile X " Front Cell Neurosci. 2015 ; 9 : 100.
Pubmed PMID: 25859182.
Nyilas R, Dudok B, Urban GM, Mackie K, Watanabe M, Cravatt BF, et al.. " Enzymatic machinery for endocannabinoid biosynthesis associated with calcium stores in glutamatergic axon terminals " J Neurosci. 2008 ; 28 (5) : 1058-63.
Pubmed PMID: 18234884.
Barna Dudok, Linlin Z. Fan, Jordan S. Farrell, Shreya Malhotra, Jesslyn Homidan, Doo Kyung Kim, Celestine Wenardy, Charu Ramakrishnan, Yulong Li, Karl Deisseroth, Ivan Soltesz. " Retrograde endocannabinoid signaling at inhibitory synapses in vivo " Science. 2024 ; 383 (6686) : 967-970.
Pubmed PMID: 38422134.