Email

Positions

Assistant Professor

Mol. & Human Gen./Jafar-Nejad
Baylor College of Medicine
Houston, TX, US

Addresses

BCM-MD Anderson Hall (Lab)

Room: BCMA-919E
Houston, TX, 77030
United States

BCM-MD Anderson Hall (Office)

Room: BCMA-919E
Houston, TX, 77030
United States

Websites

Selected Publications

• Seung Yeop Han, Ashutosh Pandey, Tereza Moore, Antonio Galeone, Lita Duraine, Tina M Cowan, Hamed Jafar-Nejad. " A conserved role for AMP-activated protein kinase in NGLY1 deficiency " PLoS Genet.. 2020 ;
  Pubmed PMID: 33315951.
• A Pandey, BM Harvey, MF Lopez, A Ito, RS Haltiwanger, H Jafar-Nejad. " Glycosylation of specific Notch EGF repeats by O-Fut1 and Fringe regulates Notch signaling in Drosophila " Cell Reports. 2019 ;
  Pubmed PMID: 31722217.
• Ashutosh Pandey*, Antonio Galeone, Seung Yeop Han, Benjamin A Story, Gaia Consonni, William F Mueller, Lars M Steinmetz, Thomas Vaccari, Hamed Jafar-Nejad*. " Gut barrier defects, intestinal immune hyperactivation and enhanced lipid catabolism drive lethality in NGLY1-deficient Drosophila " Nat Commun .. 2023 ;
  Pubmed PMID: 37704604.
• A Pandey, N Niknejad, H Jafar-Nejad. " Multifaceted regulation of Notch signaling by glycosylation " Glycobiology. 2021 ;
  Pubmed PMID: 32472127.
• Ashutosh Pandey, Joshua M Adams, Seung Yeop Han, Hamed Jafar-Nejad. " NGLY1 deficiency, a congenital disorder of deglycosylation: from disease gene function to pathophysiology " Cells. 2022 ;
  Pubmed PMID: 35406718.
• E Servián-Morilla, M Cabrera-Serrano, K Johnson, A Pandey, A Ito et al. " POGLUT1 biallelic mutations cause myopathy with reduced satellite cells, α-dystroglycan hypoglycosylation and a distinctive radiological pattern " Acta Neuropathol.. 2020 ;
  Pubmed PMID: 31897643.
• Antonio Galeone, Joshua M Adams, Shinya Matsuda, Maximiliano F Presa, Ashutosh Pandey, Seung Yeop Han, Yuriko Tachida, Hiroto Hirayama, Thomas Vaccari, Tadashi Suzuki, Cathleen M Lutz, Markus Affolter, Aamir Zuberi, Hamed Jafar-Nejad. " Regulation of BMP4/Dpp retrotranslocation and signaling by deglycosylation " eLife. 2020 ;
  Pubmed PMID: 32720893.
• Ashutosh Pandey, David Li-Kroeger, Maya K Sethi, Tom V Lee, Falk FR Buettner, Hans Bakker, Hamed Jafar-Nejad. " Sensitized genetic backgrounds reveal differential roles for EGF repeat xylosyltransferases in Drosophila Notch signaling " Glycobiology. 2018 ;
  Pubmed PMID: 30169771.
• Ashutosh Pandey, Hamed Jafar-Nejad. " Tracing the NGLY1 footprints: insights from Drosophila " J Biochem .. 2022 ;
  Pubmed PMID: 34270726.
• Tom V Lee*, Ashutosh Pandey*, Hamed Jafar-Nejad. " Xylosylation of the Notch receptor preserves the balance between its activation by trans-Delta and inhibition by cis-ligands in Drosophila " PLoS Genet.. 2017 ;
  Pubmed PMID: 28394891.