Abu Hena Mostafa Kamal
Picture
Abu Hena Mostafa Kamal
Assistant Professor
Positions
- Assistant Professor
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Department of Molecular and Cellular Biology
Baylor College of Medicine
Houston, Texas United States
- Technical Core Director
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Metabolomics Core, Advanced Technology Core
Baylor College of Medicine
Addresses
- 108CC Jones Building-ACMD (Office)
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Metabolomics Core
1 Baylor Plaza
Houston, TX 77030
United States
Phone: (713) 798-2820
abuhenamostafa.kamal@bcm.edu
Education
- BSc from Patuakhali Science and Technology University
- 05/2006 - Patuakhali, Bangladesh
- MSc from Bangladesh Agricultural University
- 12/2008 - Mymensingh, Bangladesh
- PhD from Chungbuk National University
- 08/2011 - Cheong-ju, South Korea
Professional Interests
- Metabolomics
- Proteomics
- Cancer Biology
- Mass Spectrometry
Professional Statement
I am an Assistant Professor in the Department of Molecular and Cellular Biology and the Technical Core Director of the Metabolomics Core within the Advanced Technology Core at Baylor College of Medicine (BCM). In this role, I oversee core operations, lead the development of advanced analytical methodologies, optimize existing workflows, and work closely with the Academic Director, Dr. Putluri, to drive the core’s research and strategic vision.My academic career is grounded in biological mass spectrometry and its applications in metabolomics and proteomics. My research portfolio centers on innovative method development in cancer metabolism, with particular emphasis on elucidating the metabolic effects of carcinogen exposure in bladder cancer. Beyond my research, I provide comprehensive consultation services in experimental design, data interpretation, manuscript development, and grant preparation, supporting investigators across multiple departments and collaborative institutions.
These efforts have strengthened my leadership capabilities and contributed to a rigorous and collaborative research environment within the core. As I continue to broaden my expertise, I remain committed to fostering interdisciplinary partnerships both within BCM and externally. My overarching goal is to advance state-of-the-art metabolomics and lipidomics methodologies to enable rapid, high-resolution data generation and deepen our understanding of cancer biology. Ultimately, my work aims to identify metabolic biomarkers and define critical metabolic pathways that may inform future diagnostic and therapeutic strategies.
Websites
Selected Publications
- Kamal, A. H. M.; Cho, K.; Kim, D. E.; Uozumi, N.; Chung, K. Y.; Lee, S. Y.; Choi, J. S.; Cho, S. W.; Shin, C. S.; Woo, S. H. "Changes in Physiology and Protein Abundance in Salt-Stressed Wheat Chloroplasts.." Mol. Biol. Rep.. 2012;39(9):9059–9074. Pubmed PMID: 22736107
- Kamal, A. H. M.; Cho, K.; Komatsu, S.; Uozumi, N.; Choi, J. S.; Woo, S. H. "Towards an Understanding of Wheat Chloroplasts: A Methodical Investigation of Thylakoid Proteome.." Mol. Biol. Rep.. 2012;39(5):5069–5083. Pubmed PMID: 22160430
- Kamal, A. H. M.; Cho, K.; Choi, J. S.; Bae, K. H.; Komatsu, S.; Uozumi, N.; Woo, S. H. "The Wheat Chloroplastic Proteome.." J. Proteomics. 2013;93:326–342. Pubmed PMID: 23563086
- Kamal, A. H. M.; Kim, W. K.; Cho, K.; Park, A.; Min, J. K.; Han, B. S.; Park, S. G.; Lee, S. C.; Bae, K. H. "Investigation of Adipocyte Proteome during the Differentiation of Brown Preadipocytes.." J. Proteomics. 2013;94:327–336. Pubmed PMID: 24129212
- Kamal, A. H. M.; Cho, K.; Choi, J. S.; Jin, Y.; Park, C. S.; Lee, J. S.; Woo, S. H. "Patterns of Protein Expression in Water-Stressed Wheat Chloroplasts.." Biol. Plant.. 2013;57(2):305–312.
- Kamal, A. H. M.; Han, B. S.; Choi, J.-S.; Cho, K.; Kim, S. Y.; Kim, W. K.; Lee, S. C.; Bae, K.-H. "Proteomic Analysis of the Effect of Retinoic Acids on the Human Breast Cancer Cell Line MCF-7." Mol. Biol. Rep.. 2014;41(5):3499–3507. Pubmed PMID: 24615502
- Kamal, A. H. M.; Komatsu, S. "Involvement of Reactive Oxygen Species and Mitochondrial Proteins in Biophoton Emission in Roots of Soybean Plants under Flooding Stress.." J. Proteome Res.. 2015;14(5):2219–2236.
- Kamal, A. H. M.; Rashid, H.; Sakata, K.; Komatsu, S. "Gel-Free Quantitative Proteomic Approach to Identify Cotyledon Proteins in Soybean under Flooding Stress.." J. Proteomics. 2015;112:1-13. Pubmed PMID: 25201076
- Kamal, A. H. M.; Komatsu, S. "Jasmonic Acid Induced Protein Response to Biophoton Emissions and Flooding Stress in Soybean.." J. Proteomics. 2016;133:33–47. Pubmed PMID: 26655678
- Kamal, A. H. M.; Komatsu, S. "Proteins Involved in Biophoton Emission and Flooding-Stress Responses in Soybean under Light and Dark Conditions.." Mol. Biol. Rep.. 2016;43(2):73–89. Pubmed PMID: 26754663
- Kamal, A. H. M.; Chakrabarty, J. K.; Udden, S. M. N.; Zaki, M. H.; Chowdhury, S. M. "Inflammatory Proteomic Network Analysis of Statin-Treated and Lipopolysaccharide-Activated Macrophages.." Sci. Rep (Nature). 2018;8(1):164. Pubmed PMID: 29317699
- Kamal, A. H. M.; Fessler, M. B.; Chowdhury, S. M. "Comparative and Network-Based Proteomic Analysis of Low Dose Ethanol- and Lipopolysaccharide-Induced Macrophages.." PLoS One. 2018;13(2):e0193104. Pubmed PMID: 29481576
- Kamal, A. H. M.; Aloor, J. J.; Fessler, M. B.; Chowdhury, S. "Crosslinking Proteomics Indicates Effects of Simvastatin on the TLR2 Interactome and Reveals ACTR1A as a Novel Regulator of the TLR2 Signal Cascade." Mol Cell Proteomics. 2019;18(9):1732-1744. Pubmed PMID: 31221720
- Ling Tao, Myrthala Moreno-Smith, Rodrigo Ibarra-García-Padilla, Giorgio Milazzo, Nathan A. Drolet, Blanca E. Hernandez, Young S. Oh, Ivanshi Patel, Jean J. Kim, Barry Zorman, Tajhal Patel, Abu Hena Mostafa Kamal, et. al. "CHAF1A Blocks Neuronal Differentiation and Promotes Neuroblastoma Oncogenesis via Metabolic Reprogramming." Advanced Science. 2021 Aug 8;
- Aundrea K. Westfall, Blair W. Perry, Abu H. M. Kamal, Nicole R. Hales, Jarren C. Kay, Madhab Sapkota, Drew R. Schield, Mark W. Pellegrino, Stephen M. Secor, Saiful M. Chowdhury & Todd A. Castoe "Identification of an integrated stress and growth response signaling switch that directs vertebrate intestinal regeneration." BMC Genomics. 2022 Jan 4;23(1) Pubmed PMID: 34983392
- Fujita Y, Nunez-Rubiano L, Dono A, Bellman A, Shah M, Rodriguez JC, Putluri V, Kamal AHM, Putluri N, Riascos RF, Zhu JJ, Esquenazi Y, Ballester LY. "IDH1 p.R132H ctDNA and D-2-hydroxyglutarate as CSF biomarkers in patients with IDH-mutant gliomas." J Neurooncol. 2022; Pubmed PMID: 35816267
- Kami Reddy KR, Piyarathna DWB, Kamal AHM, Putluri V, Ravi SS, Bollag RJ, Terris MK, Lotan Y, Putluri N. "Lipidomic Profiling Identifies a Novel Lipid Signature Associated with Ethnicity-Specific Disparity of Bladder Cancer." Metabolites. 2022; Pubmed PMID: 35736477
- Abu Hena Mostafa Kamal, Jayanta K. Chakrabarty and Saiful M. Chowdhury "Lipopolysaccharide and statin-mediated immune-responsive protein networks revealed in macrophages through affinity purification spacer-arm controlled cross-linking (AP-SPACC) proteomics." Molecular Omics. 2022 Oct 18;
Memberships
- American Society of Mass Spectrometry
- Member (11/2015)
- Human Proteome Organization (HUPO)
- Mmeber (01/2010)
- Dan L Duncan Comprehensive Cancer Center
- Associate Member (10/2022)
Skills
- Mass Spectrometry
- Metabolomics
- Proteomics
- Molecular Biology
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