A special issue of the journal Human Mutation contains 25 papers related to the activities of the National Human Genome Research Institute-funded Clinical Genome Resource program (ClinGen) and ClinVar.
As part of a larger effort of the National Institutes of Health’s Somatic Cell Genome Editing program, researchers received a U42 grant to create mouse model resources for testing the therapeutic potential of novel genome editing approaches.
Researches at Baylor College of Medicine, Texas Children’s Hospital and the Hospital for Sick Children have developed a new platform called INSiGHT that enables them to uncover new regulators of retina neurons.
Researchers at Baylor College of Medicine have identified a potential strategy for treating osteoarthritis from both a symptomatic and disease-modifying perspective by using gene therapy to inhibit the interleukin-1 pathway.
Predicting genes that can cause disease due to the production of truncated or altered proteins is now possible thanks to a new analytical tool to effectively and efficiently predict such candidate genes.