Genetics News

Without Dna2, genes can jump into DNA breaksDec 5, 2018
A study reveals that when Dna2 is absent, small DNA fragments jump from all over the genome into chromosome breaks. This novel mechanism may explain similar events commonly seen in cancer or during antibody diversification.
FDA recognizes database of clinically relevant genetic variantsDec 5, 2018
The database created by the Clinical Genome Resource program (ClinGen) has been recognized by the U.S. Food and Drug Administration.
Evenings with Genetics offers update on rare Angelman SyndromeNov 6, 2018
The next installment of Evenings with Genetics on Tuesday, Nov. 13, will focus on Angelman Syndrome, with expert speakers providing an update on treatment and research efforts for the disease.
Special issue of journal highlights ClinGen programOct 12, 2018
A special issue of the journal Human Mutation contains 25 papers related to the activities of the National Human Genome Research Institute-funded Clinical Genome Resource program (ClinGen) and ClinVar.
Undiagnosed Diseases Network finds 31 new syndromesOct 10, 2018
The Undiagnosed Diseases Network, a consortium of researchers including Baylor College of Medicine, Texas Children’s Hospital, Stanford University and other institutions, has found 31 new syndromes within two years of the group’s inception.
Grant funds somatic cell genome editing mouse models studyOct 9, 2018
As part of a larger effort of the National Institutes of Health’s Somatic Cell Genome Editing program, researchers received a U42 grant to create mouse model resources for testing the therapeutic potential of novel genome editing approaches.
Dynamin-binding protein linked to congenital cataractsOct 4, 2018
A new study has now found compelling evidence that links dynamin-binding protein (DNMBP) to congenital bilateral cataracts and severe vision loss. 
Researchers find missplicing Scn5a alters cardiac functionSep 28, 2018
A new study shows that reproducing in mice the missplicing of gene Scn5a observed in patients with myotonic dystrophy type 1(DM1) recapitulates defects in cardiac function present in the patients.
Baylor’s HGSC named an NIH All of Us research centerSep 26, 2018
The All of Us Research Program, part of the National Institutes of Health, has named a consortia led by Baylor's Human Genome Sequencing Center as one of three centers responsible for generating clinical grade genomic data for the program. 
Grant supports identifying leukemia, Down syndrome linkSep 18, 2018
To better understand a predisposition for acute lymphoblastic leukemia in children with Down syndrome, a team of researchers will sequence the genomes of more than 2,000 individuals with Down syndrome.