The Center for Cell and Gene Therapy at Baylor College of Medicine, Texas Children's Hospital, and Houston Methodist Hospital in Houston, Texas, provides an infrastructure to rapidly translate novel cell and gene therapy protocols from the laboratory to the clinic. The comprehensive approach of the center brings a wide variety of scientists and clinicians together to develop strategies for the treatment of cancer, HIV and cardiovascular disease.
Patient facilities include the adult stem cell transplant unit at Houston Methodist Hospital and the pediatric stem cell transplant unit at Texas Children's Hospital.
A 30,000-square-foot comprehensive adult cell and gene therapy transplant unit at Houston Methodist Hospital provides cutting-edge stem cell transplantation. Here, physician scientists have also pioneered the use of specially engineered T-cells for a variety of disorders, including cancers and genetic diseases as well as reconstituting patients’ immune systems. Work here has lead to the expansion of the therapeutic applications for stem cell transplantation, and facilitates the translation of laboratory breakthroughs into clinical cell and gene therapies. This innovative unit provides the capability for performing all types of stem cell transplantation, cellular therapy, and gene therapy.
It also provides the environment for the implementation of clinical research studies in gene therapy, transplantation involving novel conditioning regimens, and the potential role of transplantation as novel therapy for diseases such as systemic lupus erythematosus, rheumatoid arthritis, and multiple sclerosis.
Through this affiliation with Houston Methodist, patients in the adult stem cell transplant unit have access to all the specialties, including radiation therapy, diagnostic imaging, and intensive care.
The Center for Cell and Gene Therapy utilizes the pediatric stem cell transplant facility of the Texas Children's Cancer Center and Hematology Service. A 16,200-square-foot pediatric unit opened in 2001 on the 8th floor of Texas Children's Hospital, West Tower, and contains both inpatient and outpatient areas.
Through affiliation with Texas Children's, patients have access to all the pediatric specialties, including radiation therapy, diagnostic imaging and intensive care. This is especially important to transplant patients in the event of secondary complications.