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Dr. Huda Zoghbi to speak at symposium focusing on seizures
news › zoghbi-speak-symposium-focusing-on-seizures
… of pediatrics at Baylor College of Medicine and director of the Jan and Dan Duncan Neurological Research … Treatment and Research symposium. Hosted by The Brookwood Community, the event will take place at The Café at … who is also a Howard Hughes Medical Institute Investigator and the Fishman Chair in pediatric neurology research …
Study to Evaluate ARO-APOC3 in Adults with Severe Hypertriglyceridemia (H-49749)
healthcare › clinical-trials › h-49749
… The purpose of this study is to evaluate the efficacy and safety of an investigational … 500 mg/dL or higher on more than one occasion, medical history of clinical atherosclerotic cardiovascular disease or … Study to Evaluate ARO-APOC3 in Adults with Severe …
Study to evaluate seladelpar in patients with primary biliary cholangitis (H-49180)
healthcare › clinical-trials › h-49180
… cb8025-31731-re: assure: An open label long-term study to evaluate the safety and tolerability of seladelpar in subjects with primary biliary … Study to evaluate seladelpar in patients with primary biliary …
Oleic acid, a key to activating the brain’s ‘fountain of youth’
news › oleic-acid-a-key-to-activating-the-brains-fountain-of-youth
… of the process that enables learning and memory and supports proper mood regulation. The finding has paved the … Sant Pau and Pfizer Regenerative Medicine. This project was supported by the Cancer Prevention and Research Institute of …
Neighborhood-level factors contribute to liver cancer disparities across Texas
news › neighborhood-level-factors-contribute-to-liver-cancer-disparities-across-texas
… Texas has the highest rate of hepatocellular carcinoma (HCC) – the most common form of liver cancer – in the U.S. Within Texas, … at the neighborhood level, using the census tract to represent a neighborhood. They focused on measures of … Neighborhood-level factors contribute to liver cancer disparities across Texas …
Prevention of HCC Related to Metabolic Syndrome Cores and Projects
research › ... › cores-and-projects
… The goal of Project 1 is to develop HCC risk stratification models based on … > 5000 patients with cirrhosis (and 350-400 incident HCC) to develop a suite of risk score algorithms) for predicting … Alkek Department of Medicine Baylor College of Medicine Houston, Texas …
Researchers uncover how breast cancer cells become resistant to therapy
news › researchers-uncover-how-breast-cancer-cells-become-resistant-to-therapy
… About one-fourth of recurrent estrogen receptor-positive (ER+) breast cancers lose ER expression, which renders them resistant to endocrine therapy and able to grow uncontrolled. A team … explains the process but also offers possibilities to overcome it. “For years, our goal has been to tease out the …
Human norovirus GII.4 exploits unexpected entry mechanism to cause gastroenteritis
news › human-norovirus-gii-4-exploits-unexpected-entry-mechanism-to-cause-gastroenteritis
… first phase of infection – the process the virus follows to invade cells – is a decisive step in the development of … the cell membrane. The findings provide insight into the viral infection process, highlighting unique pathways … colleagues worked with human intestinal enteroids, a laboratory model of the human gastrointestinal tract that …
Boeynaems awarded CPRIT grant to study stress response in cells
news › boeynaems-awarded-cprit-grant-to-study-stress-response-in-cells
… feature of life, but some organisms are better equipped to cope and thrive during stressful periods of time. That isn’t always the case when it comes to humans. Stress at the cellular level is involved in … a human patient with aging-related Alzheimer’s disease. It appears that when cells undergo stress, the proteins tend to …
Imaging AMPA Receptors In PTSD: A Pilot Positron Emission Tomography Study (H-49839)
healthcare › clinical-trials › h-49839
… PTSD is a debilitating condition with poorly understood physiology. Through the use of medical imaging, we seek to visualize AMPA receptor density and distribution … new avenues for drug development, improve treatment outcomes, and relieve suffering of those afflicted. Up to $450 …
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