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FDA IND Clearance for STXBP1-developmental and epileptic encephalopathy therapy
news › fda-ind-clearance-for-stxbp1-developmental-and-epileptic-encephalopathy-therapy
… encephalopathy (DEE). The U.S. Food and Drug Administration has cleared the Investigational New Drug (IND) application … following intravenous administration in NHPs. “The goal of my research was always to develop a therapy that not only … to modify the disease. In NHP studies to date, CAP-002 has established transduction of more than 70% of neurons …
Bioinformatics Request Services
research › ... › services
… How do I access the Genboree Workbench for my own bioinformatics analysis? …
Module 7: Challenging Our Expectations
research › ... › module-7-challenging-our-expectations
… and use the My Plan of Action worksheet. Whenever you complete an …
ASTRO Module 7: Challenging Our Expectations
research › ... › astro-module-7-challenging-our-expectations
… and use the My Plan of Action worksheet. Whenever you complete an …
Analogy-based education improves glycemic control in diabetic patients with hyperglycemia
news › analogy-based-education-improves-glycemic-control-in-diabetic-patients-with-hyperglycemia
… not begin as a research project, but it was an attempt on my part to overcome a clinical barrier toward providing more …   “I merge these analogies into diabetes education. Once my patients understand these fundamental concepts, the … of recognition and connection in their faces and many of my patients have shared afterward that they understood …
Dr. Huda Zoghbi named the 2022 Kavli Prize Laureate in neuroscience
news › dr-huda-zoghbi-named-the-2022-kavli-prize-laureate-in-neuroscience
… Baylor College of Medicine and Texas Children’s Hospital, has been awarded the prestigious 2022 Kavli Prize in the … The Kavli Prize is a partnership among the Norwegian Academy of Science and Letters, the Norwegian Ministry of … “I am deeply honored by this recognition and credit my mentors, trainees, collaborators and the incredible …
Bone microenvironment fosters breast cancer metastatic behavior
news › bone-microenvironment-fosters-breast-cancer-metastatic-behavior
… organs is the major cause of cancer-related deaths, and my lab has been interested in this phenomenon for many years,” said … mostly metastasizes to the bone; however, it has remained a mystery why, in more than two-thirds of cases, metastases …
Brain circuit connects feeding, mood in response to stress
news › brain-connects-feeding-mood-in-stress
… of Wuhan Mental Health Center, China, when she was visiting my lab,” said corresponding author Dr. Yong Xu , associate … physical connections into another region of the brain that has numerous dopamine neurons that are implicated in the … with poor appetite. But in other cases depression has been linked to overeating. We are interested in …
About Arnold J. Rudolph
departments › ... › about-arnold-rudolph
… of life. Dr. Rudolph's lifelong interest in neonatology has been chronicled in the Atlas of the Newborn series … their lives. Nominated as an outstanding woman who has contributed significantly to the lives of all … recalls fondly, "Dr. Rudolph's emphasis on taking care of my own family was very much appreciated as I started …
Rotavirus VP3 is a unique capping machine
news › rotavirus-vp3-is-a-unique-capping-machine
… for more than 30 years, the VP3 protein of rotavirus has finally revealed its unique structure and function to a … and biochemical assays, we discovered that VP3 has all the enzymatic activities required to effectively cap rotavirus mRNA. We also found that, opposed to what has been seen in many viruses that have individual proteins …
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