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… resident SSCs. Our lab has previously identified functionally distinct P-SSCs using a combination of Mx1 and SMA to … resident P-SSCs in adult periosteum. These P-SSCS specifically express the CCL5 receptor CCR5 and CCL5 induces in vivo … Reconstruction of bone defects is important but challenging in patients with Osteogenesis Imperfecta (OI) or …
research › ... › projects
… ritualistic behaviors), and exemplifies a pathologically avoidant phenotype where greater degrees of avoidance … OCD by providing the “boost” in pro-approach behavior that allows individuals to overcome their pathological fear-based … axes underlying the pathophysiology of OCD. Our overall goal is to develop a mechanistic understanding of DBS …
news › brain-stars-hold-our-memories
… have been explained by the activity of brain cells called neurons that respond to learning events and control memory recall. The Baylor team expanded this theory by showing that non-neuronal cell types in the brain called astrocytes – star-shaped cells – also store memories …
news › dont-fall-for-allergies-this-season
… It’s finally fall, and as the crisp weather rolls in, many are rushing to get outside. As allergens fill the air, people should take precaution when … time outdoors this season. A Baylor College of Medicine allergist and pulmonologist provides tips to maintain …
news › winter-olympic-injuries
… “When you think of skating, you think of falls. Falling on an outstretched hand can lead to wrist fractures, … at Baylor. Knee injuries are another concern when skaters fall on their knees, which can result in patella fractures. … can experience a wide range of injuries. They can easily fall or be crushed into the boards, which can result in an …
Compound d16 reduces tumor growth and overcomes therapeutic resistance in mutant p53-bearing cancers
news › compound-d16-reduces-tumor-growth-and-overcomes-therapeutic-resistance-in-mutant-p53-bearing-cancers
… could make a difference in someone’s life one day.” The team also discovered that d16 can inhibit a DNA repair …
news › an-early-start-to-spring-allergies
… Though it technically may still be winter, spring allergies in Houston are out in full force. An expert with … and mold forecast and reviews how to properly use some allergy relief options. “All seasons can bring different … The right way to keep allergies at bay …
news › nobel-laureate-dr-william-g-kaelin-jr-to-give-baylor-commencement-address
… His research seeks to understand how, mechanistically, mutations affecting tumor-suppressor genes cause … research partnerships to address important medical challenges in support of the NIH mission. She also co-chairs … Center for Strategic and International Studies Bipartisan Alliance for Global Health Security. Gerberding formerly …
news › using-ai-to-improve-diagnosis-of-rare-genetic-disorders
… intelligence. The team developed a machine learning system called AI-MARRVEL (AIM) to help prioritize potentially causative variants for Mendelian disorders. The study … a public database of known variants and genetic analysis called Model organism Aggregated Resources for Rare Variant …
news › new-cdkl-genes-linked-to-neurodevelopmental-disorders
… Cdkl ,” Kanca said. “This was a surprise because generally seizures are associated with central nervous system … hearing and had heat-induced seizures and shorter lives. All these consequences were prevented when the normal CDKL1 … variants the researchers identified in patients only partially rescued the neurological problems observed in the flies …