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news › grb10-offers-a-potential-new-approach-for-treating-obesity
… For many people, keeping a healthy body weight can be a challenge. According to the Centers for Disease Control and … lead to a reduction of fat tissue and weight loss. When all works well, this leptin-mediated feedback loop between … that would regulate leptin activity and could potentially be used to overcome leptin resistance. The team …
news › new-policies-needed-to-maximize-psychedelics-therapeutic-potential
… Pennsylvania, American University and Harvard Law School call for creativity and collaboration at the federal and … law and policy, propose solutions to three regulatory challenges in anticipation of Food and Drug Administration … on the brink of a major opportunity to help people legally access psychedelic treatment,” said Dr. Amy McGuire , …
research › ... › services
… on.horizondiscovery.com/rnai/screening-libraries/shrna/gipz/#all for details. Please contact us for assembling custom … into Gateway-compatible destination vectors either individually or as arrayed libraries in multi-well plates. The core …
research › ... › mission-plan-steps
… help your child be successful, mission plans are made of small steps. Each step gets a little harder, and brings your … Generally, when coming up with possible mission plan steps, you … mission plan, read back through them to make sure they all relate to the fear or worry, are specific, and are …
news › long-range-neuronal-connections-drive-glioblastoma-invasion
… promoted glioma intrusion. They hypothesized that callosal projection neurons (CPNs) localized in the cortical … phenomenon. CPNs extend across the brain along the corpus callosum, a strip of white matter that connects the left and right cerebral hemispheres. “Severing the corpus callosum eliminated the neuronal activity-dependent …
news › primate-genome-sequencing-reveals-insight-into-human-evolution-and-biodiversity
… information for primates to date, covering nearly half of all existing primate species on Earth. Researchers from 24 … the consortium studies focused on hybridization of genetically distinct lineages in baboons. Researchers used whole …
news › recognizing-the-stages-of-heat-illness
… heat stroke being the most severe and dangerous of them all. A Baylor College of Medicine expert provides … if you believe the person is experiencing a heat stroke, call emergency medical services immediately. While waiting … itself. Protect your eyes with a hat and sunglasses. Gradually acclimate to the heat if you're just starting to work …
news › a-new-mechanism-by-which-rotavirus-makes-you-sick
… Severe cases result in approximately 128,000 deaths annually in infants and children worldwide. Despite intense … human gastrointestinal epithelium. They serve as biologically relevant model systems for studying human GI … and degrades DGAT1 and that eliminating DGAT1 would lead to all these downstream effects that would cause diarrhea,” …
news › unexpected-role-of-otx2-drives-aggressive-medulloblastoma
… we discovered that OTX2 also interacts with other proteins called splicing factors.” Splicing factors are involved in alternative splicing, a cellular process that allows cells to produce different proteins from the … kitchen to bake a cake,” Werbowetski-Ogilvie said. “They all begin with the same instructions, but each cook adds a …
news › understanding-what-makes-some-bladder-cancers-resistant-to-chemotherapy
… chemical tags that control their activity). “By computationally analyzing the vast information generated by the … behave differently. We found that certain isoforms – especially of proteins like ATAD1 and the RAF family – were more … resistance,” Dou said. “Wnt signaling, involving a protein called GSK3B, was more active in resistant tumors. The …