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research › ... › drosophila-genetics
… a high-throughput and in vivo genetic validation strategy, allowing us to comprehensively evaluate promising loci from … RNA-interference (RNAi) lines are available for nearly all fly genes, as well as putative overexpression lines for … aggregation and neurotoxicity in vivo. We will initially focus on genes identified by PD GWAS consortia and …
news › solving-the-cnl6-mystery-in-batten-disease
… Batten disease is a family of 13 rare, genetically distinct conditions. Collectively, they are the most … disease is a type of lysosomal storage disorder. Although all types of cells can be affected by defects in lysosomal … in neurons perturbs many cellular processes and eventually results in cell death. This leads to the progressive …
news › how-keep-germs-out-classrooms
… hands as frequently or as thoroughly as adults do – especially the younger ones,” Valdez said. “Preschool-age children … teenagers tend to put pens or pencils in their mouths and all of those things can harbor germs, especially if they shared them with someone who is ill. It’s very …
departments › ... › global-child-health-pediatrics-residency
… of global health clinical training, residents gain unparalleled exposure to diverse healthcare challenges and develop the skills needed to lead in the field … skills and perspectives needed to address critical health challenges in resource-limited settings. … Unparalleled Clinical Immersion Opportunities …
research › ... › services-descriptions
… 6-8 discrete plaques will be selected and undergo small expansion. One-third of the small expansions will be sent to you for testing transgene expression. One-third of the small expansions will be used to extract and analyze viral … With this service, you do all the cloning. Once you have inserted your transgene into …
news › two-distinct-tuberculosis-subtypes-ided-implications-for-personalized-therapy
… that a similar approach could identify distinct and clinically relevant TB endotypes, and the results exceeded our … to improve treatment outcomes for the deadliest of all bacterial infectious diseases,” adds Professor Jan …
news › model-of-the-human-nose-shows-sars-cov-2-and-rsv-infection
… reliable approach to establish human nose organoids that allow for long-term studies. Previous models were produced … can be used to study other respiratory viruses and potentially other disease-causing microbes. Other contributors to … Piedra, Xunyan Ye, Ernestina Melicoff-Portillo, Malli Rama Kanthi Yerramilli, Xi-Lei Zeng, Michael A. …
news › the-sars-cov-2-vaccine-can-support-heart-health
… be related to a variety of causes such as cytokine storm, small vessel vascular and thrombotic injury, increased … system floods the blood stream with inflammatory proteins called cytokines, attacking healthy cells as well as the … levels due to breathing difficulty resulting from the virus all can damage the heart. “In autopsy studies the presence …
departments › ... › in-memoriam-dr-harvey-levin
… Medical Branch in Galveston where he began an internationally renowned career in clinical work, teaching, and, most of all, pioneering research on traumatic brain injury. In 1995, … arts scene, including the Houston Symphony, Houston Ballet, Da Camera Society, Houston Early Music, Houston Grand …
news › a-molecular-glue-for-turning-on-human-cell-pluripotency
… expression. We found that NANOG’s properties – its naturally floppy, flexible 3D shape and a C-terminal tail that is structurally akin to prion-like proteins – enable it to achieve … Studying NANOG poses significant challenges … require high protein concentrations. To study this very challenging protein, the team resorted to highly sensitive …