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research › ... › prostate-cancer-ittmann-lab
… Prostate cancer is the most common visceral malignancy and the second leading cause of cancer death among U.S. males, with … followed by ethnicity. Prostate cancer is extremely heterogeneous in its clinical behavior, ranging from indolent … Kwabi-Addo B, Ozen M, and Ittmann M. 2004. The role of fibroblast growth …
research › ... › publications
… this link to access the full list of publications from Zhou lab: … v/myncbi/browse/collection/40337343/?sort=date&direction=descending Selected publications: 1. Ren Z, Lee J, Moosa MM, Nian Y, Hu L, Xu Z, McCoy JG, Ferreon … of an EIIC sugar transporter trapped in an inward-facing conformation. …
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… The lab is seeking a Postdoctoral Associate to apply for the the world-class CNRC Postdoctoral Fellowship program . Details on the … Contact Dr. Moran if you are a current medical trainee … The Moran Lab is not currently seeking graduate students. … : The Moran Lab offers training opportunities to undergraduates through …
research › ... › projects
… called caspase-2. Despite being the most evolutionarily conserved caspase, the role of caspase-2 in apoptosis … functions including cell division and the regulation of genomic instability. Consistent with these non-apoptotic … DNA damage, identifying a novel caspase-2 activating complex in the nucleolus that requires the nucleolar protein …
research › ... › research-areas
… As the gatekeepers of the sarcoplasmic reticulum (SR) intracellular Ca2+ reservoir, ryanodine receptors (RyR) play a central role in many Ca2+ dependent signaling pathways. Our use of animal models of RYR1-linked diseases such as malignant hyperthermia … Evidence shows that changes in muscle energy expenditure have a …
research › ... › research-projects
… Many human breast cancers are dependent on the steroid hormones, estrogen and progesterone for … receptors (PRs A and B), PDF . The steroid receptors have a complex domain structure as shown in Figure 1. … Treatment directed at reducing the mitogenic effects of estrogen …
research › ... › research-areas
… The Westbrook lab is dedicated to tackling fundamental problems in cancer biology and leveraging our … efforts on understanding triple-negative breast cancer, a common and aggressive subtype of breast cancer. But many of … Pathways into Cancer Therapies Delineating Sources and Consequences of RNA Processing Stress in Cancer Nominating …
research › ... › previous-lab-members
… Postdoctoral Fellow In the lab: September 2012-May 2019 Funding: IRACDA Postdoctoral … After leaving the Cooper lab: Assistant Professor, Department of Biological Sciences, University of Mary Washington … in a mouse model for myotonic dystrophy type 1. Hum. Mol. Genet. 27, 2789-2804. …
research › ... › projects
… broad and related areas: The mechanisms and physiological consequences of alternative splicing transitions during mammalian … at any given time; examples are below and new ideas are welcome. Contact Dr. Cooper to explore options. … Mechanism of Myotonic Dystrophy Pathogenesis …