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research › ... › drug-discovery
… The increasing prevalence of antibiotic resistance among bacterial pathogens is a … binders for a target in a pool of millions to billions of compounds. The conjugates are constructed in sequential cycles of chemical … S., Ucisik, M.N., Faver, J.C., Simmons, N., Jin, Z., Palaniappan, M., Nyshadham, P., Li, F., Campbell, J., Hu, L., …
research › ... › molecular-libraries
… The lab has a long-standing interest in the use of molecular libraries to answer questions relevant to enzyme structure and function, discovery of protein-protein … followed by functional selections and deep sequencing to study the determinants of enzyme catalysis and …
research › ... › join-the-team
… We are looking to add fun, motivated, and creative scientists to our growing team. Our lab is highly interdisciplinary and we welcome scientists of all backgrounds who are interested in … Students: … If you are an incoming BCM graduate student, contact Dr. Mustoe to discuss potential rotation …
research › ... › projects
… p16 (or p16INK4a) is a tumor suppressor gene that regulates cell cycle. p16 epimutation - inactivation of p16 by promoter DNA methylation - is one of the most common epigenetic events in human colorectal cancer. We … understanding how DNA methylation processes interplay with environmental cues (nutrition and microbiota) to guide the …
healthcare › clinical-trials › h-38855
… Currently, tamoxifen and raloxifene are the only medications … cells when given to patients with premalignant breast conditions (DCIS, LCIS, ADH, ALH) in order to know if it … cancer. Patients are randomized to take ruxolitinib or a placebo for 10-20 days leading up to surgical excision. …
news › novel-gene-variants-that-modify-risk-of-late-onset-alzheimers-disease-discovered
… Late-onset Alzheimer’s disease (LOAD) is the most common form of dementia in the elderly, affecting almost 44 million people … typically protected. Surprisingly, many individuals do not conform to these rules. Some people with APOEɛ4 remain … A novel computational approach finds 216 genes with differential variants in paradoxical populations …
research › ... › publications
… glioma. bioRxiv [Preprint]. 2024 May 10:2024.03.02.583026. doi: 10.1101/2024.03.02.583026. PMID: 38496434; PMCID: PMC10942290. Li X, Liu C, Li W, … 10.1101/2024.05.02.592289. PMID: 38746443; PMCID: PMC11092636. Tian A, Baidouri H, Kim S, Li J, Cheng X, Li Y, Chen …
research › ... › publications
… Nature Mental Health. https://doi.org/10.1101/2023.08.26.554837 Allawala, A.B., Bijanki, K.R., Adkinson, J., … Neuroscience. 9(408) DOI: 10.3389/fnhum.2015.00408. PMID: 26236221. Bijanki, K.R., Hodis, B., Magnotta, V.A., Zeien, … 47(10) 1423-1431. DOI:10.1016/j.jpsychres. 2013.05.026. PMID: 23790259. Bijanki, K.R., Arndt, S., Magnotta, …
academic-centers › ... › launching-your-space-health-career
… professionals and nurses. As more people are projected to visit space, there will be a greater need clinical providers …
news › baylor-launches-clinical-trial-for-covid-19-vaccine-booster
… and NIAID. For more information about the IDCRC, please visit www.IDCRC.org . …