July 2020: Our manuscript on the identification of BMP4 and its fly homolog Dpp as direct targets of NGLY1 was accepted by eLife.
July 2020: Our new R01 grant on the role of POGLUT1 in muscle development and disease was funded (collaboration with Darabi, Haltiwanger and Paradas groups)
May 2020: A review article by Ashutosh and Nima on the role of glycosylation in Notch signaling was accepted by Glycobiology.
March 2020: Duncan Fox, a graduate student form the Genetics & Genomic Graduate Program, has decided to join our lab!
December 2019: In collaboration with Paradas and Haltiwanger groups, we reported multiple muscular dystrophy patients with recessive POGLUT1 mutations in Acta Neuropathologica.
October 2019: Ashutosh published a paper in Cell Reports in collaboration with the Haltiwanger lab entitled Glycosylation of specific Notch EGF repeats by Ofut1 and Fringe regulates Notch signaling in Drosophila.
October 2019: Josh published a review article in Biomolecules on The roles of Notch signaling in liver development and disease.
August 2019: Josh Adams’ manuscript on the identification of Sox9 as a genetic modifier of Alagille syndrome liver phenotypes was accepted by Hepatology.
July 2019: Congratulations to Dr. Josh Adams for successfully defending his Ph.D. dissertation!
July 2019: Hamed presented our work at Grace Science Foundation Symposium and at FASEB TGFβ meeting.
May 2019: Josh published an article in JoVE to describe a method for determining bile duct density in the mouse liver.
April 2019: Maria Gonzalez joined our lab to help maintain our Drosophila stocks. Welcome Maria!
March 2019: Hamed presented a seminar at the Department of Biology and Biochemistry at University of Houston.
November 2018: Nima's poster was selected for a short talk at the Annual Meeting of the Society for Glycobiology at New Orleans.
November 2018: Nima published a commentary in Translational Research on the importance of unbiased glycomics in rare disease diagnosis and research.
October 2018: Hamed started his service as a Standing Member of the Intercellular Interactions Study Section (ICI).
August 2018: Ashutosh published a paper in Glycobiology in collaboration with Hans Bakker group to report that Drosophila Notch signaling is sensitive to the level of Notch xylosylation.
July 2018: Hamed gave a talk at Grace Science Foundation Symposium in Palo Alto, California.
July 2018: Josh gave a talk at Gordon Research Seminar on Notch signaling and presented a poster at the Gordon Research Conference on Notch signaling, both in Lewiston, Maine.
April 2018: Hamed presented a seminar at Department of Biochemistry and Biophysics, Texas A&M University, College Station, Texas.
February 2018: Hamed presented our work at Sanford-Burnham Rare Disease Day Symposium on Congenital Disorders of Glycosylation and De-glycosylation in San Diego, California.
February 2018: Josh published an Editorial in Gastroenterology entitled A new model of Alagille syndrome with broad phenotypic representation.
January 2018: Ashutosh published an article in JoVE to describe his cell-aggregation assays for Notch-ligand interactions in cis and trans.
November 2017: Hamed gave a talk at the RIKEN Symposium “Systems Glycobiology and Beyond” in Wako, Japan and presented a seminar at Department of Molecular Biochemistry, Nagoya University School of Medicine, Japan.
November 2017: Hamed was selected as the recipient of the 2017 Glycobiology Significant Achievement Award by the Society for Glycobiology and Oxford University Press. Each year, this award is given to a new or mid-career scientist who has "made a key discovery during their early careers with the potential to have a substantial impact on the glycoscience community". The award ceremony and presentation was held during the Annual Meeting of the Society for Glycobiology in Portland, Oregon.
August 2017: Antonio and Seung Yeop published a paper in eLife in collaboration with Tadashi Suzuki's group on the role of Drosophila NGLY1 in tissue-specific regulation of BMP signaling.
July 2017: Hamed presented our data in the 4th NGLY1 Global Conference sponsored by the Grace Science Foundation in Palo Alto, Calif.
April 2017: Tom and Ashutosh reported the role of Notch xylosylation in Delta-mediated trans-activation of Notch in an equal contribution paper in PLoS Genetics.
March 2017: Hamed gave a talk at the Glycobiology Gordon Conference in Ventura, California.
March 2017: Ashutosh presented a poster in the Fly Meeting in San Diego, California.
February 2017: Hamed gave a talk at Sanford-Burnham Rare Disease Day Symposium in San Diego on Alagille syndrome.