Services

IVIS bioluminescence imaging instrument - Instrument can be operated by Core users independently (with appropriate training) or with assisted use. Instrument can only be used if a reservation has been made with Core staff.

Ovivo - Conversion of 2D cells to 3D structures on CAM. Includes egg incubation, egg preparation, and tumor harvest. Does not include imaging or report.

Ovotar - Patient Derived Xenograft establishment on CAM. Includes egg incubation, egg preparation, and tumor harvest. Does not include imaging or report.

OvoMets - PCR-based human alu repeat assay for the detection of metastasis in the CAM assay.

OvoQuest - Custom bioassay kit that includes 9 eggs and 2h of tech time. This type of request includes egg incubation, egg preparation, tumor harvest, imaging and report building for 9 eggs.

Technician Time - Technical assistance. Applies to report building, tissue harvest, brightfield imaging, invasion analysis, angiogenesis analysis, etc.

Breeder Mice: Excess male mice from the Core’s SCID/Bg breeding colony are available for purchase.

PDX Generation: Transplantation of human tissue to generate a PDX model.

Viably Frozen Tissue: Viably Frozen tissue for Tissue for PDX Propagation: viably frozen or fresh tissue for re-generation of a PDX model. 

Fresh Tissue for Assays: Fresh tissue for end-point in vitro assays.

 Snap Frozen Tissue: Snap frozen PDX tissue for molecular assays.

FFPE Unstained Slides: Formalin-fixed paraffin embedded tissue of a single PDX model for IHC or IF staining.

TMA Unstained Slides: Tissue microarray of the BCM breast cancer model collection for IHC or IF staining.

Technician Time: Technical assistance which applies to training/guidance on various animal techniques, study design assistance, etc.