Professor, Clinical Vice-Chair and Chief, Division of General Surgery
Department of Surgery
Baylor College of Medicine
Director, Elkins Pancreas Center
Baylor College of Medicine
George L. Jordan, M.D. Chair in General Surgery
Baylor College of Medicine
Chief, Surgery Service Line
Baylor St. Luke’s Medical Center
Dan L Duncan Comprehensive Cancer Center
Baylor College of Medicine
Houston, Texas, United States


Oncology Research Fellowship from Ohio State University
General Surgery Residency from Ohio State University
M.D. from University of Cincinnati College of Medicine
B.A. from Wittenberg University


American Board of Surgery

Honors & Awards

America’s Top Doctors for Cancer
Top 1% of doctors in the U.S.
“Texas Super Doctor”
Master Clinician Award for Excellence in Patient Care

Professional Interests

Professional Statement

Dr. William Fisher’s clinical expertise is in the surgical treatment of pancreatic diseases including pancreatic cancer, cystic lesions of the pancreas, and pancreatitis. He also has formal training and extensive experience in advanced minimally invasive surgery. Dr. Fisher sees patients at Baylor St. Luke’s Medical Center.

Never satisfied with good but striving to provide literally the best medical care in the world is how best to describe Dr. William Fisher. As professor of surgery at Baylor College of Medicine, he participates in training the next generation of surgeons. He demonstrates to our residents and medical students, on a daily basis, the very best of all aspects of surgical care from the application of new techniques to an excellent bedside manner. He is constantly applying the very latest in medical technology balanced by his experience and a common sense approach. In short, he treats every patient exactly as he would expect a member of his immediate family to be treated.

He has been a member of Baylor faculty since 1998 and in that time he has built one of the largest clinical programs for the surgical treatment of pancreatic disease in the Houston area.

Dr. Fisher has practiced at Baylor College of Medicine since 1998, as Director of the Elkins Pancreas Center, his practice is focused entirely on pancreatic surgery. Dr. Fisher is internationally known for his clinical work as a pancreatic surgeon, basic science research, and clinical research in pancreatic cancer. As Director of the Elkins Pancreas Center at Baylor College of Medicine (BCM) he has developed and coordinates all of the clinical care for a large pancreatic cancer patient population as well as all of the basic science and clinical research related to pancreatic cancer being performed at BCM.

Dr. Fisher established a pancreatic cancer tissue resource and an extensive clinical database which serve as a vital resource for research. Dr. Fisher’s lab has studied the influence of gastrointestinal hormones, particularly somatostatin and its receptors, on pancreatic cancer growth, and the relationship between diabetes and pancreatic cancer.

Dr. Fisher has also collaborated on projects examining the role PDX-1 as an oncogene, gene therapy, oncolytic virotherapy, vaccination with virus-like particles, and adoptive immunotherapy for pancreatic cancer. He is also actively collaborating with investigators in the Human Genome Sequencing Center at BCM on studies sequencing the genome of pancreatic cancer. Dr. Fisher leads a team of research clinicians dedicated to translating discoveries from the bench to the bedside and has served as principal investigator on more than 15 clinical trials for patients with pancreatic cancer.

Selected Publications


American College of Surgeons
American Hepato-Pancreato-Biliary Association
The Association for Academic Surgery
The International Association of Pancreatology
The Society of American Gastrointestinal Endoscopic Surgeons
The Society for Surgery of the Alimentary Tract
Southwest Oncology Group
Southwestern Surgical Congress
The Zollinger Surgical Society