Positions

Professor of Medicine
Medicine-Hematology & Oncology
Baylor College of Medicine
Houston, TX, US
Professor
Department of Molecular and Cellular Biology
Baylor College of Medicine
Houston, Texas, United States
Dan L Duncan Professorship
Dan L Duncan Comprehensive Cancer Center
Baylor College of Medicine
Houston, Texas, United States
Program Director
BCM Oncology Scholars Training Program (T32)
Baylor College of Medicine
Houston, Texas, United States
Co-Director
Program in Integrative Molecular and Biomedical Sciences
Baylor College of Medicine
Professor
Program in Translational Biology and Molecular Medicine
Baylor College of Medicine

Education

PhD from Johns Hopkins University School Of Medicine
MD from National Taiwan University
Post-Doctoral Fellowship at Johns Hopkins University School of Medicine
Residency at Duke University Medical Center
Clinical Fellowship at Duke University Medical Center

Certifications

Texas Medical Board
Diplomate, American Board of Internal Medicine
Subspecialty in Medical Oncology, ABIM
Subspecialty in Hematology, ABIM

Honors & Awards

Dan Duncan Professorship of Oncology
The Leukemia & Lymphoma Society Scholar
General Motors Cancer Research Scholar
Howard Hughes Medical Institute Junior Faculty Development Award
Damon Runyon-Walter Winchell Physician Scientist Award
The Martin and Carol Macht Research Prize

Professional Interests

  • Cell cycle regulation
  • Development of cancer therapeutics
  • Clinical hematology

Professional Statement

I am a physician scientist with solid training in both clinical medicine and basic research. My lab is working on fundamental cell cycle/cell death regulation, and protein modifications, particularly focused on the pRb/E2F and p53 pathways in the oncogenic activation. We have identified several important pathways that are deregulated in cancer. My goal is to develop novel cancer therapy based on our own original discoveries.

Selected Publications

Intellectual Property

Method of treating cancer that overexpresses TopBP1
The present invention provides a method of treating cancer that overexpresses TopBP1 by administering to a patient suffering from the cancer with an effective amount of a small molecule inhibitor that binds the BRCT7/8 domain of TopBP1.
Co Inventors: Weei-Chin Lin, Pinki Chowdhury, Gregory E. Lin, Kang Liu, Yongcheng Song, Fang-Tsyr Lin