Positions

Professor
Breast Center - Fuqua
Baylor College of Medicine
Houston, TX, US
Co-Associate Director of Education
Dan L Duncan Comprehensive Cancer Center
Baylor College of Medicine
Houston, Texas, United States
Co-Leader, Nuclear Receptor Program
Dan L Duncan Comprehensive Cancer Center
Baylor College of Medicine
Houston, Texas, United States

Education

Ph.D. from University Of Texas At Houston Graduate School Of Biomedical Sciences
M.S. from University Of Houston, University Park
B.Sc. from University Of Houston, University Park

Certifications

Professor
Baylor College of Medicine

Honors & Awards

PROFESSOR

Professional Interests

  • Breast cancer
  • Hormone receptors, hormone responsiveness, gene expression profiling, mutant ER, metastasis, predictive markers

Memberships

AACR
ASCO

Funding

CHARACTERIZATION OF NUCLEAR RECEPTOR AND CO-REGULATOR EXPRESSION AND FUNCTION IN BREAST CANCERS
- #RP120732-P2
Grant funding from CPRIT
The goals of this project are to define NR and CoReg expression profiles in breast tumor clinical subtypes, cell lines, and primary human tumor xenografts in immunocompromised mice and to evaluate the efficacy of targeting specific overexpressed NRs and CoRegs for therapeutic intervention in breast cancer growth and survival
RESTORING HORMONE SENSITIVITY OF LATE RECURRENCES IN BREAST CANCER PATIENTS
- #PG12221410
Grant funding from Komen Foundation
The overall goal of this proposal is to use novel preclinical models developed for these studies and equally unique patient samples to study resistance markers associated with late recurrence, to develop novel drug strategies to target the SRCs and upstream kinases, and to utilize whole exome sequencing of primary breast tumors with late recurrences

Intellectual Property

Heat shock/stress response proteins and prognosis in cancer
Methods for detection of estrogen receptor beta and methods for the diagnosis and classification of cancer
Methods and compositions in breast cancer diagnosis and therapeutics
RNA expression profile predicting response to tamoxifen in breast cancer patients

Skills

SCIENTIST