Shaji K Chacko, Ph.D.

Instructor

Email

schacko@bcm.edu

Positions

Instructor: Pediatrics-Nutrition
Baylor College of Medicine
Houston, TX, US

Addresses

Children's Nutrition Research Center (Office): Room: CNRC-7005
Houston, TX, 77030
United States
https://www.bcm.edu/departments/pediatrics/sections-divisions-centers/childrens-nutrition-research-center

Education

BS from Nagpur University: 05/1990 - Nagpur, Maharashtra, India

MS from Barkatullah University: 05/1992 - Bhopal, Madhya Pradesh, India

MS from University Of Houston, Clear Lake: 05/2000 - Houston, Texas, United States

PhD from University Of Groningen: 01/2011 - Groningen, Netherlands; Medical Sciences

Websites

VIICTR Publications List

Selected Publications

Sekizkardes H, Chung ST, Chacko S, Haymond MW, Startzell M, Walter M, Walter PJ, Lightbourne M, Brown RJ. " Free fatty acid processing diverges in human pathologic insulin resistance conditions " J Clin Invest.. 2020 ;
Pubmed PMID: 32191645.
Baykal AP, Parks EJ, Shamburek R, Syed-Abdul MM, Chacko S, Cochran E, Startzell M, Gharib AM, Ouwerkerk R, Abd-Elmoniem KZ, Walter PJ, Walter M, Muniyappa R, Chung ST, Brown RJ. " Leptin decreases de novo lipogenesis in patients with lipodystrophy " JCI insight. 2020 ;
Pubmed PMID: 32573497.
Cravalho CKL, Meyers AG, Mabundo LS, Courville A, Yang S, Cai H, Dai Y, Walter M, Walter PJ, Sharma S, Chacko S, Cogen F, Magge SN, Haymond MW, Chung ST. " Metformin improves blood glucose by increasing incretins independent of changes in gluconeogenesis in youth with type 2 diabetes " Diabetologia. 2020 ;
Pubmed PMID: 32728891.
Axelsson AS, Tubbs E, Mecham B, Chacko S, Nenonen HA, Tang Y, Fahey JW, Derry JMJ, Wollheim CB, Wierup N, Haymond MW, Friend SH, Mulder H, Rosengren AH. " Sulforaphane reduces hepatic glucose production and improves glucose control in patients with type 2 diabetes " Sci Transl Med. 2017 ;
Pubmed PMID: 28615356.
Webster CC, Noakes TD, Chacko SK, Swart J, Kohn TA, Smith JA.. " Gluconeogenesis during endurance exercise in cyclists habituated to a long-term low carbohydrate high-fat diet. " J Physiol. 2016 Aug 1; 594 (15) : 4389-405.
Pubmed PMID: 26918583.
Chung ST, Chacko SK, Sunehag AL, Haymond MW.. " Measurements of Gluconeogenesis and Glycogenolysis: A Methodological Review. " Diabetes. 2015 Dec ; 64 (12) : 3996-4010.
Pubmed PMID: 26604176.
Chacko SK, Sunehag AL, Sharma S, Sauer PJ, Haymond MW. " Measurement of gluconeogenesis using glucose fragments and mass spectrometry after ingestion of deuterium oxide " J. Appl. Physiol.. 2008 Apr ; 104 (4) : 944-51.
Pubmed PMID: 18187615.
Chacko SK, Sunehag AL. " Gluconeogenesis continues in premature infants receiving total parenteral nutrition " Arch. Dis. Child. Fetal Neonatal Ed.. 2010 Nov ; 95 (6) : F413-8.
Pubmed PMID: 20682577.
de Betue CT, Verbruggen SC, Schierbeek H, Chacko SK, Bogers AJ, van Goudoever JB, Joosten KF. " Does a reduced glucose intake prevent hyperglycemia in children early after cardiac surgery? a randomized controlled crossover study " Crit Care. 2012 Oct 2; 16 (5) : R176.
Pubmed PMID: 23031354.
Quaye E, Chacko S, Chung S,...Brown R.. " Energy expenditure due to gluconeogenesis in insulin resistance " AJPEM. 2021 Oct ;
Pubmed PMID: 34693755.
Riedijk MA, Stoll B, Chacko S, Schierbeek H, Sunehag AL, van Goudoever JB, Burrin DG. " Methionine transmethylation and transsulfuration in the piglet gastrointestinal tract. " Proc. Natl. Acad. Sci. U.S.A.. 2007 Feb 27; 104 (9) : 3408-13.
Pubmed PMID: 17360659.
Chacko SK, Ordonez J, Sauer PJ, Sunehag AL. " Gluconeogenesis is not regulated by either glucose or insulin in extremely low birth weight infants receiving total parenteral nutrition. " J. Pediatr.. 2011 Jun ; 158 (6) : 891-6.
Pubmed PMID: 21324479.