Professor of Surgery
Cardiothoracic Transplantation & Circulatory Support
Baylor College of Medicine
Houston, TX, US
Chief, Center for Cardiac Support
Baylor St. Luke's Medical Center
Chief, Cardiopulmonary Transplantation
Texas Heart Institute
Program Director and Chief, Center for Cardiac Support
Texas Heart Institute
Director, Surgical Research, Cullen Cardiovascular Research Laboratories
Texas Heart Institute


Fellowship at Texas Heart Institute - Baylor College of Medicine
Thoracic Surgery
Residency at Baylor College of Medicine
Residency at Baylor College of Medicine
General Surgery
MD from Baylor College of Medicine
BS from University of Texas at Austin


Thoracic Surgery
American Board of Thoracic Surgery
General Surgery
American Board of Surgery

Honors & Awards

2009 Best of the Best
Houston’s Top Docs - Physicians Who May One Day Save Your Life”
The Country's Best Heart Doctors"
Wilhelm Scholê International Cosmopolis Award
Ray C. Fish Award for Scientific Achievement
America’s Top Doctors
Living Legend Award
America’s Top Doctors
First Annual “Gift to Mankind” Award
Best Doctors in America
The Best Medical Specialists in North America

Professional Statement

For more than 30 years, Dr. O. H. Frazier has been a pioneer in the treatment of severe heart failure and in the fields of heart transplantation and artificial devices that may be used either to substitute for or assist the pumping action of the human heart. As a result of his work, the Texas Heart Institute has become one of the top transplantation and mechanical circulatory support programs in the world. Dr. Frazier has performed over 1,200 heart transplants and implanted more than 900 left ventricular assist devices, more than any other surgeon in the world.

Dr. Frazier’s interest in mechanical circulatory support began in 1969, when, as a student at Baylor College of Medicine, he wrote a research paper about the experimental total artificial heart, which was first implanted in 1969 by Dr. Denton Cooley. Throughout the 1970s and 1980s, Dr. Frazier continued experimental work toward developing an implantable left ventricular assist device (LVAD) to aid the failing heart. In 2011, Dr. Frazier implanted the first successful continuous-flow total artificial heart using two second generation HeartMate II LVADs to replace a patient’s failing heart.

Selected Publications


American College of Cardiology
American College of Surgeons
Denton A. Cooley Cardiovascular Surgical Society