
Websites
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Positions
- Assistant Professor
- Pathology & Immunology
- Center for Cell and Gene Therapy
- Baylor College of Medicine
- Houston, TX, US
- Member
- Dan L Duncan Comprehensive Cancer Center
- Baylor College of Medicine
- Houston, Texas, United States
Education
- PhD from Baylor College of Medicine
Professional Interests
- Immunobiology of chimeric antigen receptor (CAR) T cells
- Adoptive T cell therapy of cancer and autoimmune diseases
- Synthetic biology in cell therapies
Selected Publications
- Gomes-Silva D, Srinivasan M, Sharma S, Lee CM, Wagner DL, Davis TH, Rouce RH, Bao G, Brenner MK, Mamonkin M. "CD7-edited T cells expressing a CD7-specific CAR for the therapy of T-cell malignancies.." Blood. 2017 July Pubmed PMID: 28539325
- Gomes-Silva D, Mukherjee M, Srinivasan M, Krenciute G, Dakhova O, Zheng Y, Cabral JMS, Rooney CM, Orange JS, Brenner MK, Mamonkin M. "Tonic 4-1BB Costimulation in Chimeric Antigen Receptors Impedes T Cell Survival and Is Vector-Dependent." Cell Rep. 2017 October Pubmed PMID: 28978471
- Mamonkin M, Mukherjee M, Srinivasan M, Sharma S, Gomes-Silva D, Mo F, Krenciute G, Orange JS, Brenner MK. "Reversible Transgene Expression Reduces Fratricide and Permits 4-1BB Costimulation of CAR T Cells Directed to T-Cell Malignancies." Cancer Immunol Res. 2017 October 27 Pubmed PMID: 29079655
- Mamonkin M, Rouce RH, Tashiro H, Brenner MK.. "A T-cell-directed chimeric antigen receptor for the selective treatment of T-cell malignancies.." Blood. 2015 August Pubmed PMID: 26056165
Funding
- P50 SPORE IN LYMPHOMA (2017-2021)
- NIH
- Translational Research Award (2018-2021)
- Leukemia and Lymphoma Society
- SCOR (2018-2023)
- Leukemia and Lymphoma Society
- High Impact High Reward (2018-2020)
- CPRIT
- Dream Team in Lymphoma
- Stand Up to Cancer