Positions

Associate Professor and Vivian L. Smith Endowed Chair in Neuroscience
Department of Neuroscience
Baylor College of Medicine
Houston, TX 77030

Education

Postdoctoral Fellowship at UCSF, San Francisco
PhD from University of Texas, Houston
BS from Drexel University, Philadelphia
BS from Drexel University, Philadelphia

Professional Interests

  • Learning & Memory in Cerebellar Circuits
  • Neural Control of Movement
  • Computational Neuroscience
  • Cerebellar Disease: Ataxia, Autism & Schizophrenia

Professional Statement

My laboratory investigates the role of cerebellar circuits in learning and memory. Our goal is to answer two fundamental questions: (1) how does the cerebellum learn from the past to predict future events, (2) how are error signals used to update and improve these predictions. To tackle these difficult questions we perform behavioral experiments in genetically modified mice and use a multidisciplinary approach that combines state-of-the-art techniques in electrophysiology, two-photon imaging and optogenetics. In addition, we build large-scale computer simulations and network models as a way to reveal general computational principles, refine our hypotheses and suggest novel research directions. Our findings will help identify therapeutic entry points for the treatment of motor and cognitive disorders like ataxia, autism and schizophrenia, all of which have been linked to cerebellar dysfunction.

Selected Publications