Email

jathoma1@texaschildrens.org

Positions

Professor

Pediatrics
Critical Care Medicine
Baylor College of Medicine
Houston, TX, US

Education

MD from Stanford University

05/1989 - Stanford, California, United States

AB from Princeton University

06/1981 - Princeton, New Jersey, United States

Romance Languages and Literature

Internship at Children's Hospital of Los Angeles

Los Angeles, CA

Pediatrics

Residency at Children's Hospital of Los Angeles

Los Angeles, CA

Pediatrics

Fellowship at Children's Medical Center of Dallas

Dallas, TX

Critical Care

Websites

Videos

Selected Publications

• Thomas JA, Tsen MF, White DJ, Horton JW. " TLR4 inactivation and rBPI(21) block burn-induced myocardial contractile dysfunction. " Am. J. Physiol. Heart Circ. Physiol.. 2002 Oct ; 283 (4) : H1645-55.
  Pubmed PMID: 12234819.
• Horton JW, Tan J, White DJ, Maass DL, Thomas JA. " Selective decontamination of the digestive tract attenuated the myocardial inflammation and dysfunction that occur with burn injury. " Am. J. Physiol. Heart Circ. Physiol.. 2004 Nov ; 287 (5) : H2241-51.
  Pubmed PMID: 15256371.
• Hansen BS, Hussain RZ, Lovett-Racke AE, Thomas JA, Racke MK. " Multiple toll-like receptor agonists act as potent adjuvants in the induction of autoimmunity. " J. Neuroimmunol.. 2006 Mar ; 172 (41276) : 94-103.
  Pubmed PMID: 16360885.
• Thomas JA, Haudek SB, Koroglu T, Tsen MF, Bryant DD, White DJ, Kusewitt DF, Horton JW, Giroir BP. " IRAK1 deletion disrupts cardiac Toll/IL-1 signaling and protects against contractile dysfunction. " Am. J. Physiol. Heart Circ. Physiol.. 2003 Aug ; 285 (2) : H597-606.
  Pubmed PMID: 12860565.
• Lin KM, Hu W, Troutman TD, Jennings M, Brewer T, Li X, Nanda S, Cohen P, Thomas J, Pasare C. " IRAK-1 bypasses priming and directly links TLRs to rapid NLRP3 inflammasome activation " Proceedings of the National Academy of Science. 2014 Jan 14; 111 (2) : 775-80.
  Pubmed PMID: 24379360.
• Thomas JA, Tsen MF, White DJ, Horton JW. " IRAK contributes to burn-triggered myocardial contractile dysfunction. " Am. J. Physiol. Heart Circ. Physiol.. 2002 Aug ; 283 (2) : H829-36.
  Pubmed PMID: 12124233.
• Binck BW, Tsen MF, Islas M, White DJ, Schultz RA, Willis MS, Garcia JV, Horton JW, Thomas JA. " Bone marrow-derived cells contribute to contractile dysfunction in endotoxic shock. " Am. J. Physiol. Heart Circ. Physiol.. 2005 Feb ; 288 (2) : H577-83.
  Pubmed PMID: 15458952.
• Dong JW, Vallejo JG, Tzeng HP, Thomas JA, Mann DL. " Innate immunity mediates myocardial preconditioning through Toll-like receptor 2 and TIRAP-dependent signaling pathways. " Am. J. Physiol. Heart Circ. Physiol.. 2010 Mar ; 298 (3) : H1079-87.
  Pubmed PMID: 20061547.
• Wan Y, Xiao H, Affolter J, Kim TW, Bulek K, Chaudhuri S, Carlson D, Hamilton T, Mazumder B, Stark GR, Thomas J, Li X. " Interleukin-1 receptor-associated kinase 2 is critical for lipopolysaccharide-mediated post-transcriptional control " J Biol Chem. 2009 Apr 17; 284 (16) : 10367-75.
  Pubmed PMID: 19224918.
• Deng C, Radu C, Diab A, Tsen MF, Hussain R, Cowdery JS, Racke MK, Thomas JA. " IL-1 receptor-associated kinase 1 regulates susceptibility to organ-specific autoimmunity. " J. Immunol.. 2003 Mar 15; 170 (6) : 2833-42.
  Pubmed PMID: 12626533.
• Verdrengh M, Thomas JA, Hultgren OH. " IL-1 receptor-associated kinase 1 mediates protection against Staphylococcus aureus infection. " Microbes Infect.. 2004 Nov ; 6 (14) : 1268-72.
  Pubmed PMID: 15555532.
• Li T, Hu J, Thomas JA, Li L. " Differential induction of apoptosis by LPS and taxol in monocytic cells. " Mol. Immunol.. 2005 May ; 42 (9) : 1049-55.
  Pubmed PMID: 15829295.
• Anton-Martin P, Thompson MT, Sheeran PD, Fischer A, Taylor D, Thomas JA. " Extubation during Pediatric Extracorporeal Membrane Oxygenation (ECMO): a single center experience,”. " Pediatric Critical Care Medicine (accepted). 2014 Nov ; 15 (8)

Show 9 more publications

Memberships

American Academy of Pediatrics

Fellow

Society of Critical Care Medicine

Member

Languages

Spanish